Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

Cross Reference

Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperthyroidism D006980 12 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Authors Title Published Journal PubMed Link
Okamoto H et al. Transformation and characterization of mutant human fibroblasts defective in peroxisome assembly. 1992 Exp. Cell Res. pmid:1639130
Contreras M et al. The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein. 1994 FEBS Lett. pmid:8187886
Singh I et al. Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. 1998 FEBS Lett. pmid:9600263
Ruan H et al. Structure of a novel diterpenoid ester, fritillahupehin from bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. 2002 Fitoterapia pmid:12234570
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Cimini A et al. TNFalpha downregulates PPARdelta expression in oligodendrocyte progenitor cells: implications for demyelinating diseases. 2003 Glia pmid:12465041
Wang HS et al. Infrared band assignments and structure of even-numbered 2-alkyl-7,7, 8, 8-tetracyanoquinodimethane in cast films--two components of the CH2 scissoring vibrations not related to crystal field splitting. 2010 Guang Pu Xue Yu Guang Pu Fen Xi pmid:20545125
Stanczak H et al. Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes. 1992 Hum. Hered. pmid:1511996
Dvoráková L et al. Eight novel ABCD1 gene mutations and three polymorphisms in patients with X-linked adrenoleukodystrophy: The first polymorphism causing an amino acid exchange. 2001 Hum. Mutat. pmid:11438993
Qiao X et al. Experimental bone marrow failure in mice ameliorated by OCH via tippling the balance of released cytokines from Th1 to Th2. 2012 Immunopharmacol Immunotoxicol pmid:22124468
Sabale V et al. Comparative evaluation of rice bran wax as an ointment base with standard base. 2009 Indian J Pharm Sci pmid:20177466
Elfalleh W et al. Fatty acids from Tunisian and Chinese pomegranate (Punica granatum L.) seeds. 2011 Int J Food Sci Nutr pmid:21118055
Lücker E et al. Transmissible spongiform encephalopathies: assessment of exposure risk in the histological working environment using GC-MS detection of fatty acids as marker for central nervous tissues. 2005 Int J Hyg Environ Health pmid:16217923
de Camargo AC et al. Gamma radiation induced oxidation and tocopherols decrease in in-shell, peeled and blanched peanuts. 2012 Int J Mol Sci pmid:22489128
Oki S et al. Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. 2005 Int. Immunol. pmid:16291659
Deon M et al. Induction of lipid peroxidation and decrease of antioxidant defenses in symptomatic and asymptomatic patients with X-linked adrenoleukodystrophy. 2007 Int. J. Dev. Neurosci. pmid:17928186
Chang D et al. Serum free fatty acids level in senile cataract. 2014 J Am Coll Nutr pmid:25079310
Fretts AM et al. Plasma phospholipid saturated fatty acids and incident atrial fibrillation: the Cardiovascular Health Study. 2014 J Am Heart Assoc pmid:24970268