Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

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Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperthyroidism D006980 12 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Deon M et al. The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy. 2006 J. Neurol. Sci. pmid:16750542
Dhaunsi GS et al. Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts. 2005 Jan-Feb Cell Biochem. Funct. pmid:15565636
Hall AM et al. Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice. 2005 J. Biol. Chem. pmid:15653672
Salas JJ et al. Very long chain fatty acid synthesis in sunflower kernels. 2005 J. Agric. Food Chem. pmid:15796615
Dhaunsi GS et al. Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue. 2005 Med Princ Pract pmid:16103719
Alderson NL et al. A novel method for the measurement of in vitro fatty acid 2-hydroxylase activity by gas chromatography-mass spectrometry. 2005 J. Lipid Res. pmid:15863841
Costachel C et al. Glycosylphosphatidylinositol-anchored fungal polysaccharide in Aspergillus fumigatus. 2005 J. Biol. Chem. pmid:16204227
Ndonye RM et al. Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH. 2005 J. Org. Chem. pmid:16323834
Hagfors L et al. Fat intake and composition of fatty acids in serum phospholipids in a randomized, controlled, Mediterranean dietary intervention study on patients with rheumatoid arthritis. 2005 Nutr Metab (Lond) pmid:16216119
Oki S et al. Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. 2005 Int. Immunol. pmid:16291659
Lücker E et al. Transmissible spongiform encephalopathies: assessment of exposure risk in the histological working environment using GC-MS detection of fatty acids as marker for central nervous tissues. 2005 Int J Hyg Environ Health pmid:16217923
Elewaut D Natural killer T cells and rheumatoid arthritis: friend or foe? 2005 Arthritis Res. Ther. pmid:15743495
Dhaunsi GS and Bitar MS Antioxidants attenuate diabetes-induced activation of peroxisomal functions in the rat kidney. 2004 Sep-Oct J. Biomed. Sci. pmid:15316130
Vargas CR et al. Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. 2004 Biochim. Biophys. Acta pmid:14732478
Nagura M et al. Alterations of fatty acid metabolism and membrane fluidity in peroxisome-defective mutant ZP102 cells. 2004 Lipids pmid:15055234
Zhang YH et al. Structural elucidation of fritillahupehin from bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia. 2004 J Asian Nat Prod Res pmid:14989377
Kemp S et al. Method for measurement of peroxisomal very-long-chain fatty acid beta-oxidation in human skin fibroblasts using stable-isotope-labeled tetracosanoic acid. 2004 Clin. Chem. pmid:15388659
Nagy K et al. An HPLC-MS approach for analysis of very long chain fatty acids and other apolar compounds on octadecyl-silica phase using partly miscible solvents. 2004 Anal. Chem. pmid:15053654
Mizuno M et al. Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice. 2004 J. Autoimmun. pmid:15571923
Alderson NL et al. The human FA2H gene encodes a fatty acid 2-hydroxylase. 2004 J. Biol. Chem. pmid:15337768