| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rubio M et al. | Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol. | 2007 | Neurosci. Lett. | pmid:17574742 |
| Jaggar SI et al. | The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. | 1998 | Neurosci. Lett. | pmid:9774165 |
| Milton NG | Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. | 2002 | Neurosci. Lett. | pmid:12384227 |
| Abalo R et al. | Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. | 2005 Jul 22-29 | Neurosci. Lett. | pmid:15936532 |
| Sinor AD et al. | Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. | 2000 | Neurosci. Lett. | pmid:10653017 |
| MartÃnez-González D et al. | Oleamide and anandamide effects on food intake and sexual behavior of rats. | 2004 | Neurosci. Lett. | pmid:15193744 |
| Abalo R et al. | Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. | 2009 | Neurosci. Lett. | pmid:19819299 |
| Németh J et al. | Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae. | 2003 | Neurosci. Lett. | pmid:12499047 |
| Rueda-Orozco PE et al. | Intrahippocampal administration of anandamide increases REM sleep. | 2010 | Neurosci. Lett. | pmid:20188142 |
| Pamplona FA et al. | Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice. | 2010 | Neurosci. Lett. | pmid:20036315 |
| Luo C et al. | Anandamide inhibits excitatory transmission to rat substantia gelatinosa neurones in a manner different from that of capsaicin. | 2002 | Neurosci. Lett. | pmid:11872246 |
| Leweke FM et al. | Elevated endogenous cannabinoids in schizophrenia. | 1999 | Neuroreport | pmid:10501554 |
| Beltramo M and Piomelli D | Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerol. | 2000 | Neuroreport | pmid:10817598 |
| Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
| Szöke E et al. | Interacting effects of capsaicin and anandamide on intracellular calcium in sensory neurones. | 2000 | Neuroreport | pmid:10884049 |
| Molina-Holgado F et al. | Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. | 1997 | Neuroreport | pmid:9223079 |
| Cottone E et al. | Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. | 2009 | Neuroreport | pmid:19293731 |
| Sparling PB et al. | Exercise activates the endocannabinoid system. | 2003 | Neuroreport | pmid:14625449 |
| Murillo-RodrÃguez E et al. | Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. | 2001 | Neuroreport | pmid:11447321 |
| Shinohara Y et al. | Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. | 2009 | Neuroreport | pmid:19734811 |
| Ishii I and Chun J | Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors. | 2002 | Neuroreport | pmid:11973452 |
| Mahler SV et al. | Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. | 2007 | Neuropsychopharmacology | pmid:17406653 |
| Izumi Y and Zorumski CF | NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. | 2012 | Neuropsychopharmacology | pmid:21993209 |
| Gunduz-Cinar O et al. | Fluoxetine Facilitates Fear Extinction Through Amygdala Endocannabinoids. | 2016 | Neuropsychopharmacology | pmid:26514583 |
| Monteleone P et al. | Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa. | 2005 | Neuropsychopharmacology | pmid:15841111 |
| Giuffrida A et al. | Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. | 2004 | Neuropsychopharmacology | pmid:15354183 |
| Morena M et al. | Neurobiological Interactions Between Stress and the Endocannabinoid System. | 2016 | Neuropsychopharmacology | pmid:26068727 |
| Centonze D et al. | A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission. | 2004 | Neuropsychopharmacology | pmid:15100701 |
| Pietrzak RH et al. | Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. | 2014 | Neuropsychopharmacology | pmid:24820537 |
| Dubreucq S et al. | Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. | 2012 | Neuropsychopharmacology | pmid:22434220 |
| Oleson EB et al. | Cannabinoid receptor activation shifts temporally engendered patterns of dopamine release. | 2014 | Neuropsychopharmacology | pmid:24345819 |
| Falenski KW et al. | FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. | 2010 | Neuropsychopharmacology | pmid:20357755 |
| Varvel SA et al. | Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. | 2007 | Neuropsychopharmacology | pmid:17047668 |
| Sarchielli P et al. | Endocannabinoids in chronic migraine: CSF findings suggest a system failure. | 2007 | Neuropsychopharmacology | pmid:17119542 |
| Bortolato M et al. | Anxiolytic-like properties of the anandamide transport inhibitor AM404. | 2006 | Neuropsychopharmacology | pmid:16541083 |
| Buczynski MW et al. | The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. | 2013 | Neuropsychopharmacology | pmid:23169348 |
| Seillier A et al. | Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CBâ‚ receptors: implications for schizophrenia. | 2013 | Neuropsychopharmacology | pmid:23563893 |
| Fernandez-Espejo E et al. | Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function. | 2004 | Neuropsychopharmacology | pmid:15010694 |
| Hill MN et al. | Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. | 2009 | Neuropsychopharmacology | pmid:19710634 |
| Stein EA et al. | Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. | 1998 | Neuropsychopharmacology | pmid:9803424 |
| Gyires K and Zádori Z | [Analysis of central mechanisms involved in gastric mucosal integrity]. | 2008 | Neuropsychopharmacol Hung | pmid:18956615 |
| Price TJ et al. | A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons. | 2005 | Neuropharmacology | pmid:15992578 |
| Moreira FA et al. | Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. | 2008 | Neuropharmacology | pmid:17709120 |
| Wise LE et al. | Evaluation of fatty acid amides in the carrageenan-induced paw edema model. | 2008 | Neuropharmacology | pmid:17675189 |
| Rubio M et al. | CB1 receptor blockade reduces the anxiogenic-like response and ameliorates the neurochemical imbalances associated with alcohol withdrawal in rats. | 2008 | Neuropharmacology | pmid:18371990 |
| Suplita RL et al. | Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. | 2005 | Neuropharmacology | pmid:16129456 |
| Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
| Suplita RL et al. | Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. | 2006 | Neuropharmacology | pmid:16316669 |
| Clapper JR et al. | The endocannabinoid system as a target for the treatment of cannabis dependence. | 2009 | Neuropharmacology | pmid:18691603 |
| Wilkerson JL et al. | The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice. | 2017 | Neuropharmacology | pmid:27890602 |