Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alzheimer Disease D000544 76 associated lipids
Anorexia D000855 8 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Ataxia D001259 20 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Body Weight D001835 333 associated lipids
Bradycardia D001919 13 associated lipids
Brain Concussion D001924 5 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Malinowska B et al. Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? 2012 Br. J. Pharmacol. pmid:22022923
Jarzimski C et al. Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? 2012 Br J Clin Pharmacol pmid:22242687
Umathe SN et al. Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor. 2012 Neuropharmacology pmid:22248639
Schulte K et al. Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. 2012 Naunyn Schmiedebergs Arch. Pharmacol. pmid:22215206
Wu X et al. Alteration of endocannabinoid system in human gliomas. 2012 J. Neurochem. pmid:22176552
Starowicz K et al. Spinal anandamide produces analgesia in neuropathic rats: possible CB(1)- and TRPV1-mediated mechanisms. 2012 Neuropharmacology pmid:22178705
Harvey BS et al. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. 2012 Neurotoxicology pmid:22233683
Gatta-Cherifi B et al. Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity. 2012 Int J Obes (Lond) pmid:21844878
Willibald J et al. Click-modified anandamide siRNA enables delivery and gene silencing in neuronal and immune cells. 2012 J. Am. Chem. Soc. pmid:22812910
Tsumura M et al. TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. 2012 Cell Calcium pmid:22656960
Fogaça MV et al. Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. 2012 Braz. J. Med. Biol. Res. pmid:22392189
Lisboa SF and Guimarães FS Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. 2012 Neuropharmacology pmid:22394688
Manna SS and Umathe SN Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures. 2012 Epilepsy Res. pmid:22386872
Lara-Celador I et al. Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats. 2012 Brain Res. pmid:22841538
Méndez-Díaz M et al. The endocannabinoid system modulates the valence of the emotion associated to food ingestion. 2012 Addict Biol pmid:21182571
Whyte LS et al. Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro. 2012 Br. J. Pharmacol. pmid:21649637
Berger WT et al. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. 2012 PLoS ONE pmid:23236415
Schmidt W et al. Cannabinoid receptor subtypes 1 and 2 mediate long-lasting neuroprotection and improve motor behavior deficits after transient focal cerebral ischemia. 2012 Neuroscience pmid:23069763
Pastuhov SI et al. Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. 2012 Nat Commun pmid:23072806
Feuerecker M et al. Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humans. 2012 May-Jun Alcohol Alcohol. pmid:22278319
Camann DE et al. Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure. 2013 J Expo Sci Environ Epidemiol pmid:22805989
Chiou LC et al. Targeting the cannabinoid system for pain relief? 2013 Acta Anaesthesiol Taiwan pmid:24529672
Martinez-Vargas M et al. Does the neuroprotective role of anandamide display diurnal variations? 2013 Int J Mol Sci pmid:24287910
Fowler CJ Transport of endocannabinoids across the plasma membrane and within the cell. 2013 FEBS J. pmid:23441874
Chiurchiù V et al. Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. 2013 Ann. Neurol. pmid:23447381
Kapoor S Modulation of intracellular pathways by anandamide and its evolving role in oncology. 2013 Eur. J. Cancer pmid:23434147
Laezza C et al. Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. 2013 Eur. J. Cancer pmid:23434151
García Mdel C et al. Impaired hypotensive responses induced by intrathecally injected drugs in fructose-fed rats. 2013 Eur. J. Pharmacol. pmid:23499700
Avraham Y et al. Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). 2013 J. Med. Chem. pmid:23384387
Gebeh AK et al. Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. 2013 J. Clin. Endocrinol. Metab. pmid:23372171
Compagnucci C et al. Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. 2013 PLoS ONE pmid:23372698
Brown I et al. Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators. 2013 Prog. Lipid Res. pmid:23103355
Blankman JL and Cravatt BF Chemical probes of endocannabinoid metabolism. 2013 Pharmacol. Rev. pmid:23512546
Seillier A et al. Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB₁ receptors: implications for schizophrenia. 2013 Neuropsychopharmacology pmid:23563893
Hawkins V and Butt A TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption. 2013 Neurobiol. Dis. pmid:23567653
Bilmin K et al. Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: implications for the methodology of the MTT tests. 2013 Folia Neuropathol pmid:23553136
Haller J et al. The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats. 2013 Psychopharmacology (Berl.) pmid:23743650
Berge K et al. Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. 2013 Lipids Health Dis pmid:23706001
Harvey BS et al. Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability. 2013 Cytokine pmid:23706402
Carr RL et al. Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. 2013 Toxicol. Sci. pmid:23761300
Li H et al. Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. 2013 Br. J. Pharmacol. pmid:23347118
Shinjyo N et al. Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. 2013 J. Neurosci. Res. pmid:23633391
Jourdan T et al. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. 2013 Nat. Med. pmid:23955712
O'Brien LD et al. Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). 2013 Br. J. Pharmacol. pmid:23991698
Malenczyk K et al. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. 2013 J. Biol. Chem. pmid:24089517
Brocato B et al. Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. 2013 Placenta pmid:24008071
Gunduz-Cinar O et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. 2013 Mol. Psychiatry pmid:22688188
Stanley CP et al. Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes. 2013 Eur. J. Pharmacol. pmid:24120371
Gunduz-Cinar O et al. Amygdala FAAH and anandamide: mediating protection and recovery from stress. 2013 Trends Pharmacol. Sci. pmid:24325918
Gustafsson SB et al. Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. 2013 Arch. Toxicol. pmid:23552853