Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim J and Alger BE | Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus. | 2004 | Nat. Neurosci. | pmid:15184902 |
| Witting A et al. | Endocannabinoids accumulate in spinal cord of SOD1 G93A transgenic mice. | 2004 | J. Neurochem. | pmid:15189359 |
| Peroni RN et al. | Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens. | 2004 | Eur. J. Pharmacol. | pmid:15189776 |
| Di Marzo V et al. | The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region. | 2004 | Bioorg. Med. Chem. | pmid:15351399 |
| Scorticati C et al. | The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15280536 |
| Rockwell CE and Kaminski NE | A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15284281 |
| Kishimoto S et al. | 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells. | 2004 | J. Biochem. | pmid:15115777 |
| Gardener MJ et al. | Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. | 2004 | Br. J. Pharmacol. | pmid:15066906 |
| Weber A et al. | Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. | 2004 | J. Lipid Res. | pmid:14729864 |
| Lees G and Dougalis A | Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. | 2004 | Brain Res. | pmid:14715144 |
| Sun YX et al. | Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. | 2004 | Biochem. J. | pmid:14998370 |
| Berger C et al. | Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia? | 2004 | J. Neurochem. | pmid:15009671 |
| Fernandez-Espejo E et al. | Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function. | 2004 | Neuropsychopharmacology | pmid:15010694 |
| McFarland MJ and Barker EL | Anandamide transport. | 2004 | Pharmacol. Ther. | pmid:15518883 |
| Ghafouri N et al. | Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. | 2004 | Br. J. Pharmacol. | pmid:15492019 |
| RodrÃguez de Fonseca F | [The endocannabinoid system and food intake control]. | 2004 Apr-Jun | Rev Med Univ Navarra | pmid:15382609 |
| Mechoulam R | The promise of advances in the field of endocannabinoids. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159675 |
| Fride E | The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159678 |
| Russo EB | Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159679 |
| Lam PM et al. | Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids. | 2005 | Br J Anaesth | pmid:15722382 |
| Oddi S et al. | Confocal microscopy and biochemical analysis reveal spatial and functional separation between anandamide uptake and hydrolysis in human keratinocytes. | 2005 | Cell. Mol. Life Sci. | pmid:15723173 |
| Ahern GP et al. | Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling. | 2005 | J. Neurosci. | pmid:15917451 |
| Glass M et al. | Misidentification of prostamides as prostaglandins. | 2005 | J. Lipid Res. | pmid:15863842 |
| Osei-Hyiaman D et al. | Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. | 2005 | J. Clin. Invest. | pmid:15864349 |
| Siegmund SV et al. | Anandamide induces necrosis in primary hepatic stellate cells. | 2005 | Hepatology | pmid:15841466 |
| Hayase T et al. | Persistent anxiogenic effects of a single or repeated doses of cocaine and methamphetamine: interactions with endogenous cannabinoid receptor ligands. | 2005 | Behav Pharmacol | pmid:16148444 |
| Ortega-Gutiérrez S et al. | Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures. | 2005 | Glia | pmid:15920730 |
| Bari M et al. | Cholesterol-dependent modulation of type 1 cannabinoid receptors in nerve cells. | 2005 | J. Neurosci. Res. | pmid:15920744 |
| Gavva NR et al. | AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15615864 |
| Myrdal SE and Steyger PS | TRPV1 regulators mediate gentamicin penetration of cultured kidney cells. | 2005 | Hear. Res. | pmid:15925202 |
| Pisani A et al. | High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients. | 2005 | Ann. Neurol. | pmid:15852389 |
| Venderova K et al. | Differential effects of endocannabinoids on [(3)H]-GABA uptake in the rat globus pallidus. | 2005 | Exp. Neurol. | pmid:15899265 |
| Monteleone P et al. | Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa. | 2005 | Neuropsychopharmacology | pmid:15841111 |
| Price TJ et al. | A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons. | 2005 | Neuropharmacology | pmid:15992578 |
| Taddei S | Evolving the concept of regulation of vascular tone in humans. | 2005 | Br. J. Pharmacol. | pmid:15997231 |
| Hohmann AG et al. | An endocannabinoid mechanism for stress-induced analgesia. | 2005 | Nature | pmid:15973410 |
| Glaser ST et al. | Anandamide transport: a critical review. | 2005 | Life Sci. | pmid:15979096 |
| Ambrosi S et al. | On the importance of anandamide structural features for its interactions with DPPC bilayers: effects on PLA2 activity. | 2005 | J. Lipid Res. | pmid:15961786 |
| Tian X et al. | The conformation, location, and dynamic properties of the endocannabinoid ligand anandamide in a membrane bilayer. | 2005 | J. Biol. Chem. | pmid:15964843 |
| Sancho R et al. | Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. | 2005 | J. Immunol. | pmid:16148147 |
| Ueda N et al. | N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: a novel enzyme of the beta-lactamase fold family releasing anandamide and other N-acylethanolamines. | 2005 | Life Sci. | pmid:15949819 |
| Gamber KM et al. | Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. | 2005 | Neuropharmacology | pmid:15949823 |
| Karava V et al. | Anandamide metabolism by Tetrahymena pyriformis in vitro. Characterization and identification of a 66 kDa fatty acid amidohydrolase. | 2005 | Biochimie | pmid:15951097 |
| Kwolek G et al. | [Influence of anandamide, the endogenous agonist of cannabinoid receptors on the circulatory system]. | 2005 | Postepy Hig Med Dosw (Online) | pmid:15928605 |
| Ueda N and Tsuboi K | [Enzymes involved in the biosynthesis and degradation of anandamide]. | 2005 | Seikagaku | pmid:16440755 |
| Ho WS and Hillard CJ | Modulators of endocannabinoid enzymic hydrolysis and membrane transport. | 2005 | Handb Exp Pharmacol | pmid:16596775 |
| Elphick MR and Egertová M | The phylogenetic distribution and evolutionary origins of endocannabinoid signalling. | 2005 | Handb Exp Pharmacol | pmid:16596778 |
| Wiley JL et al. | Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. | 2005 | Eur. J. Pharmacol. | pmid:15740725 |
| Tóth A et al. | Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1. | 2005 | Life Sci. | pmid:15820503 |
| Kraft B and Kress HG | Indirect CB2 receptor and mediator-dependent stimulation of human whole-blood neutrophils by exogenous and endogenous cannabinoids. | 2005 | J. Pharmacol. Exp. Ther. | pmid:16055676 |
| Pacher P et al. | Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15821037 |
| Poblete IM et al. | Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. | 2005 | J. Physiol. (Lond.) | pmid:16081483 |
| O'Sullivan SE et al. | The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. | 2005 | Br. J. Pharmacol. | pmid:15821751 |
| Chen J et al. | Finding of endocannabinoids in human eye tissues: implications for glaucoma. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15823551 |
| Chen JZ et al. | Preferred conformations of endogenous cannabinoid ligand anandamide. | 2005 | Life Sci. | pmid:15826873 |
| Mishima K et al. | Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism. | 2005 | Stroke | pmid:15845890 |
| Justinova Z et al. | The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys. | 2005 | J. Neurosci. | pmid:15944392 |
| Bazinet RP et al. | Rapid high-energy microwave fixation is required to determine the anandamide (N-arachidonoylethanolamine) concentration of rat brain. | 2005 | Neurochem. Res. | pmid:16176062 |
| Straiker A and Mackie K | Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. | 2005 | J. Physiol. (Lond.) | pmid:16179366 |
| Engeli S et al. | Activation of the peripheral endocannabinoid system in human obesity. | 2005 | Diabetes | pmid:16186383 |
| Maccarrone M et al. | Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. | 2005 | Mol. Hum. Reprod. | pmid:15563449 |
| Mechoulam R | Plant cannabinoids: a neglected pharmacological treasure trove. | 2005 | Br. J. Pharmacol. | pmid:16205721 |
| Thomas A et al. | Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist. | 2005 | Br. J. Pharmacol. | pmid:16205722 |
| Patel S et al. | The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity. | 2005 | J. Lipid Res. | pmid:15576840 |
| Fegley D et al. | Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15579492 |
| Li C et al. | High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor. | 2005 | J. Med. Chem. | pmid:16190768 |
| Valenti M et al. | The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake. | 2005 | J. Neurochem. | pmid:16135090 |
| Matsuda K et al. | The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. | 2005 | Tohoku J. Exp. Med. | pmid:16141678 |
| Rossato M et al. | Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function. | 2005 | J. Clin. Endocrinol. Metab. | pmid:15562018 |
| Suplita RL et al. | Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. | 2005 | Neuropharmacology | pmid:16129456 |
| Osei-Hyiaman D et al. | Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. | 2005 | Neuroendocrinology | pmid:16131814 |
| Mechoulam R and Deutsch DG | Toward an anandamide transporter. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16314567 |
| Ligresti A et al. | Endocannabinoid metabolic pathways and enzymes. | 2005 | Curr Drug Targets CNS Neurol Disord | pmid:16375679 |
| Flygare J et al. | Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. | 2005 | FEBS Lett. | pmid:16337199 |
| Voets T et al. | Sensing with TRP channels. | 2005 | Nat. Chem. Biol. | pmid:16408004 |
| Sarnataro D et al. | Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells. | 2005 | FEBS Lett. | pmid:16263116 |
| Van Sickle MD et al. | Identification and functional characterization of brainstem cannabinoid CB2 receptors. | 2005 | Science | pmid:16224028 |
| Jiang W et al. | Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. | 2005 | J. Clin. Invest. | pmid:16224541 |
| Di S et al. | Activity-dependent release and actions of endocannabinoids in the rat hypothalamic supraoptic nucleus. | 2005 | J. Physiol. (Lond.) | pmid:16239276 |
| Kim HI et al. | Anandamide suppression of Na+ currents in rat dorsal root ganglion neurons. | 2005 | Brain Res. | pmid:16256960 |
| Cabranes A et al. | Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. | 2005 | Neurobiol. Dis. | pmid:16242629 |
| Lee MG et al. | Effect of olvanil and anandamide on vagal C-fiber subtypes in guinea pig lung. | 2005 | Br. J. Pharmacol. | pmid:16056239 |
| Movahed P et al. | Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation. | 2005 | Br. J. Pharmacol. | pmid:15997233 |
| Movahed P et al. | Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists. | 2005 | J. Biol. Chem. | pmid:16081411 |
| Awumey EM et al. | Is there a role for anandamide in cardiovascular regulation? Insights from studies of endocannabinoid metabolism. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16014613 |
| Solbrig MV et al. | A role for endocannabinoids in viral-induced dyskinetic and convulsive phenomena. | 2005 | Exp. Neurol. | pmid:16022863 |
| Gaskari SA et al. | Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. | 2005 | Br. J. Pharmacol. | pmid:16025138 |
| Yamaguchi Y et al. | [Surgical stress]. | 2005 | Nihon Geka Gakkai Zasshi | pmid:16045189 |
| Wagner JA et al. | Coronary vasodilator effects of endogenous cannabinoids in vasopressin-preconstricted unpaced rat isolated hearts. | 2005 | J. Cardiovasc. Pharmacol. | pmid:16116341 |
| McPartland JM et al. | Cannabimimetic effects of osteopathic manipulative treatment. | 2005 | J Am Osteopath Assoc | pmid:16118355 |
| Schuel H and Burkman LJ | A tale of two cells: endocannabinoid-signaling regulates functions of neurons and sperm. | 2005 | Biol. Reprod. | pmid:16120829 |
| Besana A et al. | Lipids and two-pore domain K+ channels in excitable cells. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099395 |
| van der Stelt M and Di Marzo V | Anandamide as an intracellular messenger regulating ion channel activity. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099396 |
| Patsos HA et al. | The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2. | 2005 | Gut | pmid:16099783 |
| Yoshihara S et al. | Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. | 2005 | Int. Arch. Allergy Immunol. | pmid:16103691 |
| van der Stelt M et al. | Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. | 2005 | EMBO J. | pmid:16107881 |
| Lynch DL and Reggio PH | Molecular dynamics simulations of the endocannabinoid N-arachidonoylethanolamine (anandamide) in a phospholipid bilayer: probing structure and dynamics. | 2005 | J. Med. Chem. | pmid:16033262 |
| Wahn H et al. | The endocannabinoid arachidonyl ethanolamide (anandamide) increases pulmonary arterial pressure via cyclooxygenase-2 products in isolated rabbit lungs. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16055511 |
| Bari M et al. | Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis. | 2005 | J. Biol. Chem. | pmid:15657045 |
| Kim SR et al. | Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro. | 2005 | J. Neurosci. | pmid:15659603 |