Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wei D et al. | Endocannabinoid signaling mediates oxytocin-driven social reward. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26504214 |
Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
Scorticati C et al. | The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15280536 |
Morena M et al. | Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25489086 |
Alger BE | Endocannabinoids: getting the message across. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15173576 |
Liu J et al. | A biosynthetic pathway for anandamide. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16938887 |
Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |
Fegley D et al. | Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15138300 |
Felder CC et al. | Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8395053 |
Izzo AA and Deutsch DG | Unique pathway for anandamide synthesis and liver regeneration. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21490298 |
Cravatt BF et al. | Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11470906 |
Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
Liu J et al. | Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24191036 |
Wenzel D et al. | Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24167249 |
Fernández-Solari J et al. | Alcohol inhibits luteinizing hormone-releasing hormone release by activating the endocannabinoid system. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14981261 |
Schmid PC et al. | Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9108127 |
Kaczocha M et al. | Identification of intracellular carriers for the endocannabinoid anandamide. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19307565 |
Collin C et al. | Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7479747 |