Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kempe K et al. | Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. | 1996 | J. Biol. Chem. | pmid:8663381 |
Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
Cravatt BF et al. | Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. | 1996 | Nature | pmid:8900284 |
Sugiura T et al. | N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. | 1996 | J Lipid Mediat Cell Signal | pmid:8906545 |
Ueda N et al. | Enzymes for anandamide biosynthesis and metabolism. | 1996 | J Lipid Mediat Cell Signal | pmid:8906546 |
Yang ZM et al. | Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. | 1996 | Biol. Reprod. | pmid:8879486 |
Varga K et al. | Mechanism of the hypotensive action of anandamide in anesthetized rats. | 1996 | Hypertension | pmid:8843898 |
Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
Fride E and Mechoulam R | Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. | 1996 | Brain Res. Dev. Brain Res. | pmid:8873985 |
Sugiura T et al. | 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954083 |
Stein EA et al. | Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. | 1996 | Br. J. Pharmacol. | pmid:8872363 |
Boring DL et al. | Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931121 |
Berdyshev EV et al. | Anandamide--a new look on fatty acid ethanolamides. | 1996 | J Lipid Mediat Cell Signal | pmid:9029374 |
Paria BC et al. | The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. | 1996 | Mol. Reprod. Dev. | pmid:8914076 |
Sugiura T et al. | Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. | 1996 | Eur. J. Biochem. | pmid:8797835 |
Koga D et al. | High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). | 1995 Jan-Feb | Biomed. Chromatogr. | pmid:7734936 |
Edgemond WS et al. | The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. | 1995 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784462 |