Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Porter AC et al. | Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12023533 |
| Mukhopadhyay S et al. | Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12003810 |
| Kozak KR et al. | Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. | 2002 | J. Biol. Chem. | pmid:12244105 |
| Wenger T et al. | The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats. | 2002 | Life Sci. | pmid:11883716 |
| Di Marzo V et al. | A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. | 2002 | J. Pharmacol. Exp. Ther. | pmid:11861807 |
| Szallasi A | Vanilloid (capsaicin) receptors in health and disease. | 2002 | Am. J. Clin. Pathol. | pmid:12109845 |
| Dinh TP et al. | Brain monoglyceride lipase participating in endocannabinoid inactivation. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12136125 |
| Grainger J and Boachie-Ansah G | Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | 2001 | Br. J. Pharmacol. | pmid:11682448 |
| Ross RA et al. | Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. | 2001 | Br. J. Pharmacol. | pmid:11159715 |
| Vanheel B and Van de Voorde J | Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11160613 |
| Farquhar-Smith WP and Rice AS | Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. | 2001 | Anesthesiology | pmid:11374613 |
| Ralevic V et al. | Cannabinoid activation of recombinant and endogenous vanilloid receptors. | 2001 | Eur. J. Pharmacol. | pmid:11672565 |
| White R et al. | Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | 2001 | Br. J. Pharmacol. | pmid:11606334 |
| Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
| Tucker RC et al. | The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways. | 2001 | Br. J. Pharmacol. | pmid:11226144 |
| Maingret F et al. | The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. | 2001 | EMBO J. | pmid:11226154 |
| Wagner JA et al. | Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. | 2001 | Eur. J. Pharmacol. | pmid:11448486 |
| Boger DL et al. | alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412972 |
| Mendizábal VE et al. | Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. | 2001 | Eur. J. Pharmacol. | pmid:11567656 |
| Izzo AA et al. | Effect of vanilloid drugs on gastrointestinal transit in mice. | 2001 | Br. J. Pharmacol. | pmid:11264233 |
| Baker D et al. | Endocannabinoids control spasticity in a multiple sclerosis model. | 2001 | FASEB J. | pmid:11156943 |
| Tognetto M et al. | Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. | 2001 | J. Neurosci. | pmid:11160380 |
| MacCarrone M et al. | Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. | 2001 | Eur. J. Biochem. | pmid:11168423 |
| Hansen HH et al. | Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death. | 2001 | J. Neurochem. | pmid:11145976 |
| Matias I et al. | Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. | 2001 | Brain Res. Mol. Brain Res. | pmid:11245916 |
| Kurihara J et al. | 2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves. | 2001 | Jpn. J. Pharmacol. | pmid:11676206 |
| Nogueron MI et al. | Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. | 2001 | J. Neurochem. | pmid:11677265 |
| van der Stelt M et al. | Exogenous anandamide protects rat brain against acute neuronal injury in vivo. | 2001 | J. Neurosci. | pmid:11698588 |
| RodrÃguez de Fonseca F et al. | An anorexic lipid mediator regulated by feeding. | 2001 | Nature | pmid:11700558 |
| Jamshidi N and Taylor DA | Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. | 2001 | Br. J. Pharmacol. | pmid:11704633 |
| Gurwitz D and Weizman A | Fatty acid amide hydrolase inhibitors and the marijuana debate. | 2001 | Lancet | pmid:11705595 |
| Rice AS | Cannabinoids and pain. | 2001 | Curr Opin Investig Drugs | pmid:11575713 |
| Karava V et al. | Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. | 2001 | FEBS Lett. | pmid:11728445 |
| Stamer WD et al. | Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. | 2001 | Eur. J. Pharmacol. | pmid:11730719 |
| Hayase T et al. | Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. | 2001 | J. Pharm. Pharmacol. | pmid:11732755 |
| Hansen HH et al. | Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. | 2001 | J. Neurochem. | pmid:11579150 |
| Smith PJ and McQueen DS | Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. | 2001 | Br. J. Pharmacol. | pmid:11588121 |
| Maccarrone M et al. | Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. | 2001 | Arch. Biochem. Biophys. | pmid:11556820 |
| Crozier Willi G et al. | Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. | 2001 | Nestle Nutr Workshop Ser Clin Perform Programme | pmid:11510437 |
| Stella N and Piomelli D | Receptor-dependent formation of endogenous cannabinoids in cortical neurons. | 2001 | Eur. J. Pharmacol. | pmid:11513837 |
| Vellani V et al. | Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. | 2001 | J. Physiol. (Lond.) | pmid:11483711 |
| Maccarrone M et al. | Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. | 2001 | J. Neurochem. | pmid:11461969 |
| Ueda N et al. | Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. | 2001 | J. Biol. Chem. | pmid:11463796 |
| Cravatt BF et al. | Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11470906 |
| Senior K | Endogenously produced cannabinoids and liver cirrhosis. | 2001 | Lancet | pmid:11454385 |
| Stanford SJ et al. | Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. | 2001 | Br. J. Pharmacol. | pmid:11454655 |
| Mang CF et al. | Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors. | 2001 | Br. J. Pharmacol. | pmid:11522608 |
| Bradbury J | Small part of cannabis puzzle solved by animal studies. | 2001 | Lancet | pmid:11498223 |
| Jonsson KO et al. | Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. | 2001 | Br. J. Pharmacol. | pmid:11498512 |
| Berger A et al. | Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11353819 |
| Craib SJ et al. | A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. | 2001 | Br. J. Pharmacol. | pmid:11522594 |
| Hayase T et al. | Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. | 2001 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:11828716 |
| Deutsch DG et al. | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. | 2001 | J. Biol. Chem. | pmid:11118429 |
| Garcia N et al. | Systemic and portal hemodynamic effects of anandamide. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11123193 |
| Al-Hayani A et al. | The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. | 2001 | Neuropharmacology | pmid:11747904 |
| Izzo AA et al. | The gastrointestinal pharmacology of cannabinoids. | 2001 | Curr Opin Pharmacol | pmid:11757815 |
| Wagner JA et al. | Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. | 2001 | J. Am. Coll. Cardiol. | pmid:11738314 |
| Huang SM et al. | Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. | 2001 | J. Biol. Chem. | pmid:11518719 |
| López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. | 2001 | J. Med. Chem. | pmid:11741470 |
| Chemin J et al. | Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. | 2001 | EMBO J. | pmid:11742980 |
| Bifulco M et al. | Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. | 2001 | FASEB J. | pmid:11687506 |
| De Petrocellis L et al. | Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. | 2001 | FEBS Lett. | pmid:11602256 |
| Bisogno T et al. | Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. | 2001 | Br. J. Pharmacol. | pmid:11606325 |
| D'Souza DC and Kosten TR | Cannabinoid antagonists: a treatment in search of an illness. | 2001 | Arch. Gen. Psychiatry | pmid:11296092 |
| Mechoulam R and Fride E | Physiology. A hunger for cannabinoids. | 2001 | Nature | pmid:11298428 |
| Smart D et al. | Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology. | 2001 | Eur. J. Pharmacol. | pmid:11301059 |
| Bueb JL et al. | Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro. | 2001 | Biochim. Biophys. Acta | pmid:11336796 |
| Kim D and Thayer SA | Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture. | 2001 | J. Neurosci. | pmid:11319244 |
| Kagota S et al. | 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. | 2001 | Eur. J. Pharmacol. | pmid:11275004 |
| Bisogno T et al. | The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. | 2001 | Eur. J. Biochem. | pmid:11277920 |
| Jacobsson SO and Fowler CJ | Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. | 2001 | Br. J. Pharmacol. | pmid:11309246 |
| Quistad GB et al. | Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11350214 |
| Day TA et al. | Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. | 2001 | Mol. Pharmacol. | pmid:11353795 |
| Kobayashi Y et al. | Activation by 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, of p42/44 mitogen-activated protein kinase in HL-60 cells. | 2001 | J. Biochem. | pmid:11328586 |
| Möhle R et al. | Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. | 2001 | Ann. N. Y. Acad. Sci. | pmid:11458515 |
| Chang YH et al. | Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. | 2001 | J. Cell. Biochem. | pmid:11329626 |
| Olah Z et al. | Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. | 2001 | J. Biol. Chem. | pmid:11333266 |
| Calignano A et al. | Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. | 2001 | Eur. J. Pharmacol. | pmid:11426841 |
| Di Marzo V et al. | Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11181068 |
| Fride E et al. | Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. | 2001 | Eur. J. Pharmacol. | pmid:11426843 |
| Ugdyzhekova DS et al. | Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. | 2001 | Bull. Exp. Biol. Med. | pmid:11427912 |
| Di Marzo V et al. | Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. | 2001 | Biochem. J. | pmid:11485574 |
| Murillo-RodrÃguez E et al. | Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. | 2001 | Neuroreport | pmid:11447321 |
| Sprague J et al. | Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. | 2001 | Eur. J. Pharmacol. | pmid:11448475 |
| Porter AC and Felder CC | The endocannabinoid nervous system: unique opportunities for therapeutic intervention. | 2001 | Pharmacol. Ther. | pmid:11448725 |
| Laine K et al. | Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. | 2001 | Pharm. Res. | pmid:11451037 |
| Holt S et al. | Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. | 2001 | Br. J. Pharmacol. | pmid:11399668 |
| Di Marzo V et al. | Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. | 2001 | Eur. J. Pharmacol. | pmid:11408034 |
| Breivogel CS et al. | Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. | 2001 | Mol. Pharmacol. | pmid:11408610 |
| Wang Y et al. | Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. | 2001 | Anal. Biochem. | pmid:11412008 |
| De Petrocellis L et al. | The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. | 2001 | J. Neurochem. | pmid:11413249 |
| Morisset V and Urban L | Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. | 2001 | J. Neurophysiol. | pmid:11431486 |
| Bátkai S et al. | Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. | 2001 | Nat. Med. | pmid:11433348 |
| Maccarrone M et al. | Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. | 2001 | J. Immunol. | pmid:11390466 |
| Wenger T et al. | The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11394887 |
| Maccarrone M et al. | Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. | 2001 | J. Neurochem. | pmid:11208922 |
| Di Marzo V et al. | Anandamide: some like it hot. | 2001 | Trends Pharmacol. Sci. | pmid:11431028 |
| Ueda N et al. | Alkaline and acid amidases hydrolyzing anandamide and other N-acylethanolamines. | 2001 | World Rev Nutr Diet | pmid:11935959 |
| Hansen HS et al. | When and where are N-acylethanolamine phospholipids and anandamide formed? | 2001 | World Rev Nutr Diet | pmid:11935960 |
| Berdyshev EV et al. | Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. | 2001 | FASEB J. | pmid:11641243 |