Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Zhang J et al. | Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. | 2013 | Sheng Li Xue Bao | pmid:23598867 |
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Ohsaka Y and Nishino H | 3T3-L1 adipocytes possess anandamide- and epinephrine-responsive machinery for MDM2 distribution to the plasma membrane. | 2013 | Gen. Physiol. Biophys. | pmid:23682023 |
Roy A et al. | Stress peptide PACAP engages multiple signaling pathways within the carotid body to initiate excitatory responses in respiratory and sympathetic chemosensory afferents. | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23594614 |
Bishay P et al. | Anandamide deficiency and heightened neuropathic pain in aged mice. | 2013 | Neuropharmacology | pmid:23597506 |
Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
Li Q et al. | Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. | 2013 | PLoS ONE | pmid:23667607 |
Lobato NS et al. | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. | 2013 | PLoS ONE | pmid:23667622 |
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Lenglet S et al. | Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23241405 |
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Citraro R et al. | Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. | 2013 | Neuropharmacology | pmid:23206503 |
Dékány A et al. | The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. | 2013 | Basic Clin. Pharmacol. Toxicol. | pmid:23216932 |
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Avraham Y et al. | Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). | 2013 | J. Med. Chem. | pmid:23384387 |
Gebeh AK et al. | Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23372171 |
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Oh HA et al. | Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos. | 2013 | Mol. Hum. Reprod. | pmid:23112252 |
Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |
Abán C et al. | Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis. | 2013 | Placenta | pmid:23122699 |
Romero TR et al. | Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors. | 2013 | Life Sci. | pmid:23123446 |
Guindon J et al. | Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. | 2013 | Pharmacol. Res. | pmid:23127915 |
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Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Pedroza-Llinás R et al. | CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning. | 2013 | Behav. Brain Res. | pmid:23018128 |
Li Q et al. | Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart. | 2013 | J Physiol Sci | pmid:23007622 |
Rivera P et al. | Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. | 2013 | Eur. J. Neurosci. | pmid:23033907 |
Starowicz K et al. | Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. | 2013 | PLoS ONE | pmid:23573230 |
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Morgan CJ et al. | Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. | 2013 | Br J Psychiatry | pmid:23580381 |
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Bilmin K et al. | Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: implications for the methodology of the MTT tests. | 2013 | Folia Neuropathol | pmid:23553136 |
Haller J et al. | The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats. | 2013 | Psychopharmacology (Berl.) | pmid:23743650 |
Berge K et al. | Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. | 2013 | Lipids Health Dis | pmid:23706001 |
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Derbenev AV and Smith BN | Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. | 2013 | PLoS ONE | pmid:23936221 |
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Adinolfi B et al. | Anticancer activity of anandamide in human cutaneous melanoma cells. | 2013 | Eur. J. Pharmacol. | pmid:24041928 |
Fonseca BM et al. | The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. | 2013 | Apoptosis | pmid:24048885 |
Khlaifia A et al. | Anandamide, cannabinoid type 1 receptor, and NMDA receptor activation mediate non-Hebbian presynaptically expressed long-term depression at the first central synapse for visceral afferent fibers. | 2013 | J. Neurosci. | pmid:23904599 |
Citraro R et al. | CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. | 2013 | Epilepsy Res. | pmid:23860329 |
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Shinjyo N et al. | Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. | 2013 | J. Neurosci. Res. | pmid:23633391 |
Leung K et al. | Role of FAAH-like anandamide transporter in anandamide inactivation. | 2013 | PLoS ONE | pmid:24223930 |
Maione S et al. | Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. | 2013 | Pharmacol. Res. | pmid:23911581 |
Jourdan T et al. | Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. | 2013 | Nat. Med. | pmid:23955712 |
O'Brien LD et al. | Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). | 2013 | Br. J. Pharmacol. | pmid:23991698 |
Malenczyk K et al. | CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. | 2013 | J. Biol. Chem. | pmid:24089517 |
Brocato B et al. | Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. | 2013 | Placenta | pmid:24008071 |
Gunduz-Cinar O et al. | Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. | 2013 | Mol. Psychiatry | pmid:22688188 |
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