Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gouveia-Figueira S et al. | Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. | 2015 | PLoS ONE | pmid:26406890 |
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Malek N et al. | Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. | 2015 | Neural Plast. | pmid:26090232 |
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Krishnan G and Chatterjee N | Differential immune mechanism to HIV-1 Tat variants and its regulation by AEA [corrected]. | 2015 | Sci Rep | pmid:25943894 |
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Nicholson J et al. | Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis. | 2015 | PLoS ONE | pmid:25835291 |
Patsenker E et al. | Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. | 2015 | Int J Mol Sci | pmid:25826533 |
Gray JM et al. | Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. | 2015 | J. Neurosci. | pmid:25740517 |
Walentiny DM et al. | Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice. | 2015 | Neuropharmacology | pmid:25698527 |
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Monteleone AM et al. | Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. | 2015 | Am. J. Clin. Nutr. | pmid:25646322 |
Gaskari SA et al. | Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids. | 2015 | J. Hepatol. | pmid:25640062 |
Lisboa SF et al. | Increased Contextual Fear Conditioning in iNOS Knockout Mice: Additional Evidence for the Involvement of Nitric Oxide in Stress-Related Disorders and Contribution of the Endocannabinoid System. | 2015 | Int. J. Neuropsychopharmacol. | pmid:25618404 |
Kumar S | Computational identification and binding analysis of orphan human cytochrome P450 4X1 enzyme with substrates. | 2015 | BMC Res Notes | pmid:25595103 |
Sadhasivam S et al. | Novel associations between FAAH genetic variants and postoperative central opioid-related adverse effects. | 2015 | Pharmacogenomics J. | pmid:25558980 |
Karlsson C et al. | Baseline anandamide levels and body weight impact the weight loss effect of CB1 receptor antagonism in male rats. | 2015 | Endocrinology | pmid:25549047 |
Uhelski ML et al. | Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy. | 2015 | J. Neurophysiol. | pmid:25505113 |
Liu J and Pope C | The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats. | 2015 | Neurotoxicology | pmid:25447325 |
Wang ZY et al. | Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase. | 2015 | J. Mol. Neurosci. | pmid:25374388 |
Troy-Fioramonti S et al. | Acute activation of cannabinoid receptors by anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice. | 2015 | Diabetes | pmid:25281429 |
Scotchie JG et al. | Endocannabinoid regulation in human endometrium across the menstrual cycle. | 2015 | Reprod Sci | pmid:24819878 |
Qi M et al. | A robust capillary liquid chromatography/tandem mass spectrometry method for quantitation of neuromodulatory endocannabinoids. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26411510 |
Cascio MG and Marini P | Biosynthesis and Fate of Endocannabinoids. | 2015 | Handb Exp Pharmacol | pmid:26408157 |
Piyanova A et al. | Age-related changes in the endocannabinoid system in the mouse hippocampus. | 2015 | Mech. Ageing Dev. | pmid:26278494 |
Mecha M et al. | Endocannabinoids drive the acquisition of an alternative phenotype in microglia. | 2015 | Brain Behav. Immun. | pmid:26086345 |
Manduca A et al. | Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats. | 2015 | Eur Neuropsychopharmacol | pmid:25914159 |
Llorente-Berzal A et al. | 2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons. | 2015 | Psychopharmacology (Berl.) | pmid:25814137 |
Pisanti S et al. | Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration. | 2015 | J. Cell. Physiol. | pmid:25684344 |
Aliczki M et al. | Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. | 2015 | Psychopharmacology (Berl.) | pmid:25547462 |
Urquhart P et al. | Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases. | 2015 | Biochim. Biophys. Acta | pmid:25543004 |
Ford GK et al. | Involvement of the endocannabinoid system in attentional modulation of nociceptive behaviour in rats. | 2015 | Eur J Pain | pmid:25504741 |
Sticht MA et al. | Intra-visceral insular cortex 2-arachidonoylglycerol, but not N-arachidonoylethanolamide, suppresses acute nausea-induced conditioned gaping in rats. | 2015 | Neuroscience | pmid:25499318 |
Grzeda E et al. | Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus. | 2015 | J. Physiol. Pharmacol. | pmid:26084216 |
Orellana-Serradell O et al. | Proapoptotic effect of endocannabinoids in prostate cancer cells. | 2015 | Oncol. Rep. | pmid:25606819 |
Pacioni G et al. | Truffles contain endocannabinoid metabolic enzymes and anandamide. | 2015 | Phytochemistry | pmid:25433633 |
Park SW et al. | Anticancer effects of anandamide on head and neck squamous cell carcinoma cells via the production of receptor-independent reactive oxygen species. | 2015 | Head Neck | pmid:24797795 |
Wollank Y et al. | Inhibition of FAAH confers increased stem cell migration via PPARα. | 2015 | J. Lipid Res. | pmid:26263913 |
Almada M et al. | Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator. | 2015 | Biochim. Biophys. Acta | pmid:26335727 |
Vilela LR et al. | Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. | 2015 | Toxicol. Appl. Pharmacol. | pmid:25933444 |