Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Correa F et al. | Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. | 2010 | Glia | pmid:19565660 |
Ali AB and Todorova M | Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. | 2010 | Eur. J. Neurosci. | pmid:20345910 |
Frampton G et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. | 2010 | Exp. Cell Res. | pmid:20347808 |
Kim J and Alger BE | Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. | 2010 | Nat. Neurosci. | pmid:20348918 |
Hansen HS | Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain. | 2010 | Exp. Neurol. | pmid:20353771 |
Soltys J et al. | Regulation of neural progenitor cell fate by anandamide. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20691161 |
Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
Ziegler CG et al. | Expression and function of endocannabinoid receptors in the human adrenal cortex. | 2010 | Horm. Metab. Res. | pmid:19862666 |
Romigi A et al. | Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy. | 2010 | Epilepsia | pmid:19817812 |
Dey R et al. | Endocannabinoids inhibit the growth of free-living amoebae. | 2010 | Antimicrob. Agents Chemother. | pmid:20479202 |
Burdyga G et al. | Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20430875 |
Hill MN et al. | Endogenous cannabinoid signaling is essential for stress adaptation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20439721 |
Ying-Ying Y and Lin HC | Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. | 2010 | Liver Int. | pmid:20408944 |
Spradley JM et al. | Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. | 2010 | Pharmacol. Res. | pmid:20416378 |
Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
Sántha P et al. | The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons. | 2010 | Acta Physiol Hung | pmid:20511124 |
Talevi R et al. | Is there a role for endocannabinoids in sperm-oviduct interaction? | 2010 | Reproduction | pmid:20511399 |
Suárez J et al. | Endocannabinoid system in the adult rat circumventricular areas: an immunohistochemical study. | 2010 | J. Comp. Neurol. | pmid:20533360 |
Weis F et al. | Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery. | 2010 | Br J Anaesth | pmid:20525978 |
Jumpertz R et al. | Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide. | 2010 | Exp. Clin. Endocrinol. Diabetes | pmid:20429051 |
Izzo AA and Sharkey KA | Cannabinoids and the gut: new developments and emerging concepts. | 2010 | Pharmacol. Ther. | pmid:20117132 |
Lerner TN et al. | Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. | 2010 | J. Neurosci. | pmid:20147543 |
Jenkin KA et al. | Role for cannabinoid receptors in human proximal tubular hypertrophy. | 2010 | Cell. Physiol. Biochem. | pmid:21220919 |
Ueda N et al. | N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). | 2010 | Prog. Lipid Res. | pmid:20152858 |
Tanimura A et al. | The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. | 2010 | Neuron | pmid:20159446 |
Chadwick W et al. | Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. | 2010 | PLoS ONE | pmid:21179406 |
Touriño C et al. | FAAH deficiency promotes energy storage and enhances the motivation for food. | 2010 | Int J Obes (Lond) | pmid:20029375 |
Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
Annuzzi G et al. | Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. | 2010 | Lipids Health Dis | pmid:20426869 |
Mair KM et al. | Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. | 2010 | Br. J. Pharmacol. | pmid:20718749 |
Cozzolino R et al. | A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. | 2010 | Invest New Drugs | pmid:19189054 |
Barana A et al. | Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. | 2010 | Cardiovasc. Res. | pmid:19689982 |
Prestifilippo JP et al. | Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. | 2009 Sep-Oct | Alcohol Alcohol. | pmid:19589828 |
Ferreira SG et al. | N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. | 2009 | Neuropharmacology | pmid:19101577 |
Ozalp A and Barroso B | Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. | 2009 | Anal. Biochem. | pmid:19665986 |
Karbarz MJ et al. | Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. | 2009 | Anesth. Analg. | pmid:19095868 |
Vignali M et al. | The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. | 2009 | Glia | pmid:19031444 |
Fernandez-Solari J et al. | Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448903 |
Ribeiro A et al. | Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448906 |
Li D et al. | Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. | 2009 | J. Hypertens. | pmid:19462497 |
Mahmud A et al. | Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. | 2009 | Neuroscience | pmid:19463903 |
Vann RE et al. | Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. | 2009 | Eur. J. Pharmacol. | pmid:19470387 |
Vercelli CA et al. | Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. | 2009 | Reprod. Biomed. Online | pmid:19490788 |
Aquila S et al. | A new role of anandamide in human sperm: focus on metabolism. | 2009 | J. Cell. Physiol. | pmid:19492411 |
Kingsley PJ and Marnett LJ | Analysis of endocannabinoids, their congeners and COX-2 metabolites. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19505857 |
Dowie MJ et al. | Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. | 2009 | Neuroscience | pmid:19524019 |
Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
Maeda N et al. | Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. | 2009 | Fundam Clin Pharmacol | pmid:19527302 |
Straiker A and Mackie K | Cannabinoid signaling in inhibitory autaptic hippocampal neurons. | 2009 | Neuroscience | pmid:19501632 |
Kinsey SG et al. | Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19502530 |
Catanzaro G et al. | Anandamide increases swelling and reduces calcium sensitivity of mitochondria. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19679102 |
Fraga D et al. | Endogenous cannabinoids induce fever through the activation of CB1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19681872 |
Lozovaya N et al. | Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. | 2009 | Cell Calcium | pmid:19682741 |
Okamoto Y et al. | Enzymatic formation of anandamide. | 2009 | Vitam. Horm. | pmid:19647106 |
Yates ML and Barker EL | Organized trafficking of anandamide and related lipids. | 2009 | Vitam. Horm. | pmid:19647107 |
Goodfellow CE and Glass M | Anandamide receptor signal transduction. | 2009 | Vitam. Horm. | pmid:19647109 |
Brown AJ and Robin Hiley C | Is GPR55 an anandamide receptor? | 2009 | Vitam. Horm. | pmid:19647110 |
Correa FG et al. | The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. | 2009 | Vitam. Horm. | pmid:19647114 |
Tóth A et al. | Anandamide and the vanilloid receptor (TRPV1). | 2009 | Vitam. Horm. | pmid:19647120 |
Pasquariello N et al. | Regulation of gene transcription and keratinocyte differentiation by anandamide. | 2009 | Vitam. Horm. | pmid:19647122 |
Alpini G and Demorrow S | Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. | 2009 | Vitam. Horm. | pmid:19647123 |
Astarita G et al. | Targeted lipidomics as a tool to investigate endocannabinoid function. | 2009 | Int. Rev. Neurobiol. | pmid:19607960 |
Francavilla F et al. | Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. | 2009 | Endocrinology | pmid:19608651 |
Centonze D et al. | Altered anandamide degradation in attention-deficit/hyperactivity disorder. | 2009 | Neurology | pmid:19398708 |
Liu H et al. | Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. | 2009 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:19399401 |
Balas L et al. | Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. | 2009 | J. Med. Chem. | pmid:19161308 |
Guindon J and Hohmann AG | The endocannabinoid system and pain. | 2009 | CNS Neurol Disord Drug Targets | pmid:19839937 |
Vercelli CA et al. | Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. | 2009 | Placenta | pmid:19428101 |
Li Q et al. | Electrophysiological effects of anandamide on rat myocardium. | 2009 | Br. J. Pharmacol. | pmid:20050190 |
Hiley CR | Endocannabinoids and the heart. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19276990 |
Gratzke C et al. | Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. | 2009 | J. Urol. | pmid:19237169 |
El-Talatini MR et al. | Localisation and function of the endocannabinoid system in the human ovary. | 2009 | PLoS ONE | pmid:19238202 |
Correa F et al. | A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. | 2009 | Biochem. Pharmacol. | pmid:18848818 |
McCue JM et al. | In vitro synthesis of arachidonoyl amino acids by cytochrome c. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19683594 |
Cottone E et al. | Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. | 2009 | Neuroreport | pmid:19293731 |
Villanueva A et al. | Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. | 2009 | Shock | pmid:19295473 |
Izzo AA et al. | Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. | 2009 | Br. J. Pharmacol. | pmid:19371345 |
Appendino G et al. | Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. | 2009 | J. Med. Chem. | pmid:19361197 |
El-Talatini MR et al. | Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. | 2009 | Hum. Reprod. | pmid:19363040 |
Brizzi A et al. | New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. | 2009 | J. Med. Chem. | pmid:19331413 |
Koethe D et al. | Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. | 2009 | Br J Psychiatry | pmid:19336792 |
Mangieri RA et al. | An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | 2009 | Psychopharmacology (Berl.) | pmid:19343330 |
Potenzieri C et al. | Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. | 2009 | Brain Res. | pmid:19285051 |
De Petrocellis L and Di Marzo V | An introduction to the endocannabinoid system: from the early to the latest concepts. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285257 |
Catani MV et al. | Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. | 2009 | J. Mol. Med. | pmid:18820887 |
Cano C et al. | Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. | 2009 | Eur J Med Chem | pmid:19762126 |
Centonze D et al. | Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. | 2009 | Neurol. Sci. | pmid:19768368 |
Jean-Gilles L et al. | Plasma endocannabinoid levels in multiple sclerosis. | 2009 | J. Neurol. Sci. | pmid:19695579 |
Wyffels L et al. | Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. | 2009 | Bioorg. Med. Chem. | pmid:19054678 |
Rossi F et al. | The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. | 2009 | Bone | pmid:19059369 |
Jiang LS et al. | Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. | 2009 | Cardiovasc. Res. | pmid:19074161 |
Aneetha H et al. | Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19013794 |
Panlilio LV et al. | Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. | 2009 | Psychopharmacology (Berl.) | pmid:19015836 |
De Petrocellis L et al. | Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. | 2009 | J. Lipid Res. | pmid:19017617 |
Tuboly G et al. | Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. | 2009 | Clin. Exp. Pharmacol. Physiol. | pmid:19018802 |
Schacht JP et al. | Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. | 2009 | Psychopharmacology (Berl.) | pmid:19002671 |
Araújo JR et al. | Effect of cannabinoids upon the uptake of folic acid by BeWo cells. | 2009 | Pharmacology | pmid:19145103 |