Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lam PM et al. | Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma. | 2008 | Anal. Biochem. | pmid:18555789 |
Horvath G et al. | The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level. | 2008 | Pain | pmid:17533116 |
Moloney GP et al. | Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor. | 2008 | Eur J Med Chem | pmid:17582659 |
Zolese G et al. | Effect of acylethanolamides on lipid peroxidation and paraoxonase activity. | 2008 | Biofactors | pmid:19478424 |
Snider NT et al. | The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18698000 |
Ortar G et al. | Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation. | 2008 | Eur J Med Chem | pmid:17452063 |
Malvindi MA et al. | Rod-shaped nanocrystals elicit neuronal activity in vivo. | 2008 | Small | pmid:18844306 |
Liu J et al. | Multiple pathways involved in the biosynthesis of anandamide. | 2008 | Neuropharmacology | pmid:17631919 |
Shaladi AM et al. | [Cannabinoids in the control of pain]. | 2008 | Recenti Prog Med | pmid:19388223 |
Rossi C et al. | Endocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: relation with serotonin levels. | 2008 | Eur. J. Clin. Pharmacol. | pmid:18004553 |
Di Marzo V et al. | The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. | 2008 | Br. J. Pharmacol. | pmid:18223666 |
Simon GM and Cravatt BF | Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain. | 2008 | J. Biol. Chem. | pmid:18227059 |
Burstein S | The elmiric acids: biologically active anandamide analogs. | 2008 | Neuropharmacology | pmid:18187165 |
Maccarrone M et al. | Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. | 2008 | Nat. Neurosci. | pmid:18204441 |
Paradisi A et al. | Anandamide regulates keratinocyte differentiation by inducing DNA methylation in a CB1 receptor-dependent manner. | 2008 | J. Biol. Chem. | pmid:18165231 |
Jackson SN et al. | Volatile anesthetics and endogenous cannabinoid anandamide have additive and independent inhibitory effects on alpha(7)-nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes. | 2008 | Eur. J. Pharmacol. | pmid:18242598 |
Butt C et al. | Endogenous cannabinoid anandamide inhibits nicotinic acetylcholine receptor function in mouse thalamic synaptosomes. | 2008 | J. Neurochem. | pmid:18194436 |
Oddi S et al. | Evidence for the intracellular accumulation of anandamide in adiposomes. | 2008 | Cell. Mol. Life Sci. | pmid:18213445 |
Baldassano S et al. | Cannabinoid CB(1) receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle. | 2008 | Eur. J. Pharmacol. | pmid:18234188 |
Starowicz KM et al. | Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. | 2008 | Obesity (Silver Spring) | pmid:18239598 |
Moreira FA et al. | Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. | 2008 | Neuropharmacology | pmid:17709120 |
Habayeb OM et al. | Plasma anandamide concentration and pregnancy outcome in women with threatened miscarriage. | 2008 | JAMA | pmid:18334688 |
Oláh M et al. | The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG. | 2008 | Mol. Cell. Endocrinol. | pmid:18308464 |
Potvin S et al. | Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy. | 2008 | J. Psychopharmacol. (Oxford) | pmid:18308802 |
Hill MN et al. | Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. | 2008 | Pharmacopsychiatry | pmid:18311684 |
Migliarini B and Carnevali O | Anandamide modulates growth and lipid metabolism in the zebrafish Danio rerio. | 2008 | Mol. Cell. Endocrinol. | pmid:18342434 |
De Oliveira Alvares L et al. | Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms. | 2008 | Neurobiol Learn Mem | pmid:18342551 |
Palkovits M et al. | Regional distribution and effects of postmortal delay on endocannabinoid content of the human brain. | 2008 | Neuroscience | pmid:18343585 |
Fezza F et al. | Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation. | 2008 | J. Lipid Res. | pmid:18316795 |
Gertsch J | Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. | 2008 | Planta Med. | pmid:18275004 |
Roberts LA et al. | Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro. | 2008 | Neuropharmacology | pmid:17631916 |
Gonçalves P et al. | Lack of a significant effect of cannabinoids upon the uptake of 2-deoxy-D-glucose by Caco-2 cells. | 2008 | Pharmacology | pmid:18431074 |
McFarland MJ et al. | RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells. | 2008 | Mol. Pharmacol. | pmid:18436710 |
Nomura DK et al. | Activation of the endocannabinoid system by organophosphorus nerve agents. | 2008 | Nat. Chem. Biol. | pmid:18438404 |
Ortar G et al. | New tetrazole-based selective anandamide uptake inhibitors. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18424134 |
Bisogno T | Endogenous cannabinoids: structure and metabolism. | 2008 | J. Neuroendocrinol. | pmid:18426492 |
Capasso R and Izzo AA | Gastrointestinal regulation of food intake: general aspects and focus on anandamide and oleoylethanolamide. | 2008 | J. Neuroendocrinol. | pmid:18426498 |
Ahn K et al. | Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. | 2008 | Chem. Rev. | pmid:18429637 |
Rubio M et al. | CB1 receptor blockade reduces the anxiogenic-like response and ameliorates the neurochemical imbalances associated with alcohol withdrawal in rats. | 2008 | Neuropharmacology | pmid:18371990 |
Evans RM et al. | Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites. | 2008 | Br. J. Pharmacol. | pmid:18376419 |
Di Marzo V and Maccarrone M | FAAH and anandamide: is 2-AG really the odd one out? | 2008 | Trends Pharmacol. Sci. | pmid:18394720 |
Kaufmann I et al. | Anandamide and neutrophil function in patients with fibromyalgia. | 2008 | Psychoneuroendocrinology | pmid:18395993 |
Hegde VL et al. | Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. | 2008 | Mol. Pharmacol. | pmid:18388242 |
Solinas M et al. | The endocannabinoid system in brain reward processes. | 2008 | Br. J. Pharmacol. | pmid:18414385 |
Richardson D et al. | Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. | 2008 | Arthritis Res. Ther. | pmid:18416822 |
Farrell EK and Merkler DJ | Biosynthesis, degradation and pharmacological importance of the fatty acid amides. | 2008 | Drug Discov. Today | pmid:18598910 |
Engel MA et al. | Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. | 2008 | J. Physiol. Pharmacol. | pmid:19212003 |
Mallat A and Lotersztajn S | Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis. | 2008 | Diabetes Metab. | pmid:19195630 |
Palmer JA et al. | Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. | 2008 | Neuroscience | pmid:18541380 |
Yao F et al. | Development of novel tail-modified anandamide analogs. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18723350 |
Di Marzo V | Endocannabinoids: synthesis and degradation. | 2008 | Rev. Physiol. Biochem. Pharmacol. | pmid:18481028 |
Pertwee RG | Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. | 2008 | Addict Biol | pmid:18482430 |
Rueda-Orozco PE et al. | Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats. | 2008 | Neuropharmacology | pmid:18501388 |
Di Filippo M et al. | Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis. | 2008 | J. Neurol. Neurosurg. Psychiatr. | pmid:18535023 |
Kase Y et al. | Removal of 2-arachidonylglycerol by direct hemoperfusion therapy with polymyxin B immobilized fibers benefits patients with septic shock. | 2008 | Ther Apher Dial | pmid:18937720 |
Ashton JC et al. | Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists. | 2008 | Curr. Med. Chem. | pmid:18537620 |
Njie YF et al. | N-arachidonylethanolamide-induced increase in aqueous humor outflow facility. | 2008 | Invest. Ophthalmol. Vis. Sci. | pmid:18539938 |
Wang J et al. | Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells. | 2008 | J. Biochem. | pmid:18806270 |
Feizi A et al. | The preventive effect of cannabinoids on reperfusion-induced ischemia of mouse kidney. | 2008 | Exp. Toxicol. Pathol. | pmid:18571910 |
Habayeb OM et al. | Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation. | 2008 | Endocrinology | pmid:18599552 |
Waldeck-Weiermair M et al. | Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression. | 2008 | J. Cell. Sci. | pmid:18445684 |
Resstel LB et al. | Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. | 2008 | Psychopharmacology (Berl.) | pmid:18446325 |
Cippitelli A et al. | Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. | 2008 | Psychopharmacology (Berl.) | pmid:18446329 |
Liu HY et al. | [Effects of anandamide on the activation and proliferation of hepatic stellate cells through cannabinoid-2 receptors]. | 2008 | Zhonghua Gan Zang Bing Za Zhi | pmid:18578993 |
Dembiński A et al. | Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves. | 2008 | Eur. J. Pharmacol. | pmid:18593574 |
Stark K et al. | Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide. | 2008 | FEBS J. | pmid:18549450 |
Khasabova IA et al. | A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. | 2008 | J. Neurosci. | pmid:18971457 |
Hill MN et al. | Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. | 2008 | J Neural Transm | pmid:18974922 |
Kamei J et al. | [Sensitization of cough sensitivity through activation of C-and/or Adelta fibers]. | 2008 | Nippon Yakurigaku Zasshi | pmid:18552444 |
Thors L et al. | Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids. | 2008 | Br. J. Pharmacol. | pmid:18552875 |
Ellgren M et al. | Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. | 2008 | Eur Neuropsychopharmacol | pmid:18674887 |
Fowler CJ and Ghafouri N | Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? | 2008 | Pharmacol. Res. | pmid:18675915 |
Hashiguchi T et al. | Systematic evaluation of nitric oxide, tetrahydrobiopterin, and anandamide levels in a porcine model of endotoxemia. | 2008 | J Anesth | pmid:18685926 |
Maione S et al. | Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. | 2008 | Br. J. Pharmacol. | pmid:18660824 |
Fowler CJ | "The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. | 2008 | Curr. Pharm. Des. | pmid:18781976 |
McPartland JM et al. | Cannabimimetic effects modulated by cholinergic compounds. | 2008 | Addict Biol | pmid:18782385 |
Ferreri C et al. | Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation. | 2008 | Bioorg. Med. Chem. | pmid:18782671 |
Rácz I et al. | Anandamide effects on 5-HT(3) receptors in vivo. | 2008 | Eur. J. Pharmacol. | pmid:18775693 |
Neelands TR et al. | Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons. | 2008 | Inflamm. Res. | pmid:18777111 |
Placzek EA et al. | Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. | 2008 | J. Neurochem. | pmid:18778304 |
Scherma M et al. | Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18725543 |
Ho WS et al. | 'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. | 2008 | Br. J. Pharmacol. | pmid:18695637 |
Woodward DF et al. | The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products. | 2008 | Pharmacol. Ther. | pmid:18700152 |
Williams JL et al. | K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18703414 |
Moezi L et al. | Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18703639 |
de Oliveira Alvares L et al. | Opposite action of hippocampal CB1 receptors in memory reconsolidation and extinction. | 2008 | Neuroscience | pmid:18554811 |
Cella M et al. | Dual effect of anandamide on rat placenta nitric oxide synthesis. | 2008 | Placenta | pmid:18561998 |
Placzek EA et al. | Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. | 2008 | Neuropharmacology | pmid:18760289 |
Nakata M and Yada T | Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors. | 2008 | Regul. Pept. | pmid:17884194 |
Haller VL et al. | Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. | 2008 | Eur. J. Pharmacol. | pmid:18762181 |
Astarita G et al. | Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain. | 2008 | J. Lipid Res. | pmid:17957091 |
da Veiga MA et al. | Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion. | 2008 | J. Endocrinol. | pmid:18755884 |
Qin N et al. | TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. | 2008 | J. Neurosci. | pmid:18550765 |
Lehtonen M et al. | Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. | 2008 | Chem. Biodivers. | pmid:19035572 |
DeMorrow S et al. | Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18096608 |
Scherma M et al. | The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition. | 2008 | Neuropharmacology | pmid:17904589 |
Butler RK et al. | Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: opioid receptor dependency and molecular correlates. | 2008 | Pain | pmid:19004548 |
Rubino T et al. | Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. | 2008 | Cereb. Cortex | pmid:17921459 |
Gyires K and Zádori Z | [Analysis of central mechanisms involved in gastric mucosal integrity]. | 2008 | Neuropsychopharmacol Hung | pmid:18956615 |
Muccioli GG and Stella N | An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. | 2008 | Anal. Biochem. | pmid:17981259 |