Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Weis F et al. | Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery. | 2010 | Br J Anaesth | pmid:20525978 |
Jarzimski C et al. | Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? | 2012 | Br J Clin Pharmacol | pmid:22242687 |
Morgan CJ et al. | Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. | 2013 | Br J Psychiatry | pmid:23580381 |
Koethe D et al. | Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. | 2009 | Br J Psychiatry | pmid:19336792 |
Pei R et al. | Low-fat yogurt consumption reduces biomarkers of chronic inflammation and inhibits markers of endotoxin exposure in healthy premenopausal women: a randomised controlled trial. | 2017 | Br. J. Nutr. | pmid:29179781 |
Okine BN et al. | Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. | 2012 | Br. J. Pharmacol. | pmid:22595021 |
Sun Y et al. | Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. | 2007 | Br. J. Pharmacol. | pmid:17906680 |
Ryberg E et al. | The orphan receptor GPR55 is a novel cannabinoid receptor. | 2007 | Br. J. Pharmacol. | pmid:17876302 |
Ross RA et al. | Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. | 2001 | Br. J. Pharmacol. | pmid:11159715 |
White R and Hiley CR | The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. | 1998 | Br. J. Pharmacol. | pmid:9806337 |
Köfalvi A et al. | Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. | 2007 | Br. J. Pharmacol. | pmid:17435795 |
Roberts LA et al. | Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons. | 2002 | Br. J. Pharmacol. | pmid:12359623 |
White R et al. | Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | 2001 | Br. J. Pharmacol. | pmid:11606334 |
Tucker RC et al. | The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways. | 2001 | Br. J. Pharmacol. | pmid:11226144 |
Woodhams SG et al. | Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. | 2012 | Br. J. Pharmacol. | pmid:22924700 |
Ghasemi M et al. | Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. | 2007 | Br. J. Pharmacol. | pmid:17486141 |
Fraga D et al. | Endogenous cannabinoids induce fever through the activation of CB1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19681872 |
Van den Bossche I and Vanheel B | Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. | 2000 | Br. J. Pharmacol. | pmid:10960073 |
Lau BK et al. | Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. | 2014 | Br. J. Pharmacol. | pmid:25041240 |
Hillard CJ and Jarrahian A | Cellular accumulation of anandamide: consensus and controversy. | 2003 | Br. J. Pharmacol. | pmid:12970089 |
O'Sullivan SE et al. | Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistance and conduit rat mesenteric arteries. | 2004 | Br. J. Pharmacol. | pmid:15148250 |
Randall MD et al. | The complexities of the cardiovascular actions of cannabinoids. | 2004 | Br. J. Pharmacol. | pmid:15131000 |
Romano MR and Lograno MD | Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels. | 2006 | Br. J. Pharmacol. | pmid:16474412 |
Di Marzo V et al. | The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. | 2008 | Br. J. Pharmacol. | pmid:18223666 |
De Petrocellis L et al. | A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. | 2012 | Br. J. Pharmacol. | pmid:22861649 |
Ho WS and Randall MD | Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. | 2007 | Br. J. Pharmacol. | pmid:17245358 |
Wheal AJ et al. | Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. | 2007 | Br. J. Pharmacol. | pmid:17245361 |
Makwana R et al. | Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation. | 2010 | Br. J. Pharmacol. | pmid:20233228 |
Gamaleddin I et al. | The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. | 2011 | Br. J. Pharmacol. | pmid:21501143 |
Howlett AC et al. | Endocannabinoid tone versus constitutive activity of cannabinoid receptors. | 2011 | Br. J. Pharmacol. | pmid:21545414 |
Booker L et al. | The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. | 2012 | Br. J. Pharmacol. | pmid:21506952 |
Jamshidi N and Taylor DA | Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. | 2001 | Br. J. Pharmacol. | pmid:11704633 |
Shouman B et al. | Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. | 2006 | Br. J. Pharmacol. | pmid:16682966 |
McHugh D et al. | Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. | 2012 | Br. J. Pharmacol. | pmid:21595653 |
O'Sullivan SE et al. | The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. | 2005 | Br. J. Pharmacol. | pmid:15821751 |
Randall MD | The cardiovascular actions of anandamide: more targets? | 2005 | Br. J. Pharmacol. | pmid:15834438 |
Kwolek G et al. | Central and peripheral components of the pressor effect of anandamide in urethane-anaesthetized rats. | 2005 | Br. J. Pharmacol. | pmid:15834445 |
Guindon J et al. | Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. | 2011 | Br. J. Pharmacol. | pmid:21198549 |
Craib SJ et al. | A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. | 2001 | Br. J. Pharmacol. | pmid:11522594 |
White R and Hiley CR | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | Br. J. Pharmacol. | pmid:9422801 |
Zygmunt PM et al. | Studies on the effects of anandamide in rat hepatic artery. | 1997 | Br. J. Pharmacol. | pmid:9422814 |
Scherma M et al. | The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. | 2012 | Br. J. Pharmacol. | pmid:21557729 |
Lever IJ and Malcangio M | CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. | 2002 | Br. J. Pharmacol. | pmid:11786475 |
Moezi L et al. | Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors. | 2006 | Br. J. Pharmacol. | pmid:17043671 |
Izzo AA et al. | Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. | 2009 | Br. J. Pharmacol. | pmid:19371345 |
Maione S et al. | Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. | 2008 | Br. J. Pharmacol. | pmid:18660824 |
Kagaya M et al. | Characterization of the anandamide induced depolarization of guinea-pig isolated vagus nerve. | 2002 | Br. J. Pharmacol. | pmid:12183329 |
Gardiner SM et al. | Complex regional haemodynamic effects of anandamide in conscious rats. | 2002 | Br. J. Pharmacol. | pmid:11959791 |
Jia Y et al. | Anandamide induces cough in conscious guinea-pigs through VR1 receptors. | 2002 | Br. J. Pharmacol. | pmid:12411414 |
Geraghty DP and Mazzone SB | Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. | 2002 | Br. J. Pharmacol. | pmid:12411424 |