Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Caraceni P et al. | Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. | 2010 | Liver Int. | pmid:19840245 |
Buznikov GA et al. | A putative 'pre-nervous' endocannabinoid system in early echinoderm development. | 2010 | Dev. Neurosci. | pmid:19907129 |
Kaczocha M et al. | Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. | 2010 | J. Biol. Chem. | pmid:19926788 |
Aquila S et al. | Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. | 2010 | Anat Rec (Hoboken) | pmid:19938110 |
Wiley JL and Burston JJ | Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:19941884 |
Piccinetti CC et al. | Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. | 2010 | Gen. Comp. Endocrinol. | pmid:19800340 |
Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
Amoako AA et al. | Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21056015 |
Godlewski G et al. | Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. | 2010 | Chem. Biol. | pmid:21095576 |
Di Marzo V | Anandamide serves two masters in the brain. | 2010 | Nat. Neurosci. | pmid:21102567 |
Zakrzeska A et al. | A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. | 2010 | Br. J. Pharmacol. | pmid:20105178 |
Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. | 2010 | Br. J. Pharmacol. | pmid:20590569 |
Rajesh M et al. | Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. | 2010 | Br. J. Pharmacol. | pmid:20590572 |
Wheal AJ et al. | Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. | 2010 | Br. J. Pharmacol. | pmid:20590573 |
Gutierrez-Lopez MD et al. | Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. | 2010 | Br. J. Pharmacol. | pmid:20590579 |
Soneji ND et al. | Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. | 2010 | Life Sci. | pmid:20598325 |
Patsos HA et al. | The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. | 2010 | Int. J. Oncol. | pmid:20514410 |
Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
Muccioli GG et al. | The endocannabinoid system links gut microbiota to adipogenesis. | 2010 | Mol. Syst. Biol. | pmid:20664638 |
Clapper JR et al. | Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | 2010 | Nat. Neurosci. | pmid:20852626 |
Jenkin KA et al. | Role for cannabinoid receptors in human proximal tubular hypertrophy. | 2010 | Cell. Physiol. Biochem. | pmid:21220919 |
Oz M et al. | The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism. | 2010 | J. Neurochem. | pmid:20050977 |
Yang Q et al. | Anandamide induces cell death through lipid rafts in hepatic stellate cells. | 2010 | J. Gastroenterol. Hepatol. | pmid:20059638 |
Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
Aquila S et al. | Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. | 2010 | Br. J. Pharmacol. | pmid:20067470 |
Marczylo TH et al. | Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:20026294 |
Touriño C et al. | FAAH deficiency promotes energy storage and enhances the motivation for food. | 2010 | Int J Obes (Lond) | pmid:20029375 |
Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
Cozzolino R et al. | A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. | 2010 | Invest New Drugs | pmid:19189054 |
Barana A et al. | Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. | 2010 | Cardiovasc. Res. | pmid:19689982 |
Gratzke C et al. | Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147270 |
Prieto D | Editorial comment on: localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147273 |
Prestifilippo JP et al. | Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. | 2009 Sep-Oct | Alcohol Alcohol. | pmid:19589828 |
Doroshenko P and Renaud LP | Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. | 2009 | Neuroscience | pmid:19135504 |
Koethe D et al. | Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. | 2009 | J Neural Transm | pmid:19137236 |
Adermark L et al. | Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. | 2009 | Eur. J. Neurosci. | pmid:19120438 |
Wang J and Ueda N | Biology of endocannabinoid synthesis system. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19126434 |
Acone G et al. | Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. | 2009 | Placenta | pmid:19097644 |
Wheal AJ and Randall MD | Effects of hypertension on vasorelaxation to endocannabinoids in vitro. | 2009 | Eur. J. Pharmacol. | pmid:19100733 |
EscartÃn-Pérez RE et al. | Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. | 2009 | Physiol. Behav. | pmid:19150453 |
Eckardt K et al. | Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. | 2009 | Diabetologia | pmid:19089403 |
Karbarz MJ et al. | Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. | 2009 | Anesth. Analg. | pmid:19095868 |
Vignali M et al. | The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. | 2009 | Glia | pmid:19031444 |
Fernandez-Solari J et al. | Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448903 |
Ribeiro A et al. | Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448906 |
Palandra J et al. | Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19535304 |
Fonseca BM et al. | Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. | 2009 | Placenta | pmid:19560819 |
Guasti L et al. | Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. | 2009 | Mol Pain | pmid:19570201 |
Bittner S et al. | TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. | 2009 | Brain | pmid:19570851 |
Grimaldi P et al. | The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19541620 |
Grider JR et al. | Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19589944 |
Batetta B et al. | Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. | 2009 | J. Nutr. | pmid:19549757 |
Catanzaro G et al. | Anandamide increases swelling and reduces calcium sensitivity of mitochondria. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19679102 |
Fraga D et al. | Endogenous cannabinoids induce fever through the activation of CB1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19681872 |
Lozovaya N et al. | Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. | 2009 | Cell Calcium | pmid:19682741 |
Okamoto Y et al. | Enzymatic formation of anandamide. | 2009 | Vitam. Horm. | pmid:19647106 |
Hill MN et al. | Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. | 2009 | Psychoneuroendocrinology | pmid:19394765 |
Chen L et al. | Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. | 2009 | J Pain | pmid:19409856 |
Yang YY et al. | Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. | 2009 | Liver Int. | pmid:19413671 |
Hansen HS and Diep TA | N-acylethanolamines, anandamide and food intake. | 2009 | Biochem. Pharmacol. | pmid:19413995 |
Zoerner AA et al. | Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19414283 |
Di Pasquale E et al. | The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. | 2009 | PLoS ONE | pmid:19330032 |
Trezza V and Vanderschuren LJ | Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. | 2009 | J. Pharmacol. Exp. Ther. | pmid:18948500 |
Pelorosso FG et al. | The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. | 2009 | Eur. J. Pharmacol. | pmid:19022239 |
Gervasi MG et al. | The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. | 2009 | Reproduction | pmid:19042982 |
Guindon J and Beaulieu P | The role of the endogenous cannabinoid system in peripheral analgesia. | 2009 | Curr Mol Pharmacol | pmid:20021453 |
Fonseca BM et al. | Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. | 2009 | Reprod. Biol. Endocrinol. | pmid:19860893 |
Abalo R et al. | Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. | 2009 | Neurosci. Lett. | pmid:19819299 |
Järbe TU et al. | Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. | 2009 | Psychopharmacology (Berl.) | pmid:18521574 |
Bajo M et al. | Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. | 2009 | J. Neurosci. Res. | pmid:18816788 |
Long JZ et al. | Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. | 2009 | Nat. Chem. Biol. | pmid:19029917 |
Vural IM et al. | Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. | 2009 | J Sex Med | pmid:19175867 |
Garcia-Ovejero D et al. | The endocannabinoid system is modulated in response to spinal cord injury in rats. | 2009 | Neurobiol. Dis. | pmid:18930143 |
Musella A et al. | TRPV1 channels facilitate glutamate transmission in the striatum. | 2009 | Mol. Cell. Neurosci. | pmid:18930149 |
Meuth SG et al. | The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. | 2009 | Neurobiol. Dis. | pmid:18930826 |
Sun X et al. | Genetic loss of Faah compromises male fertility in mice. | 2009 | Biol. Reprod. | pmid:18987328 |
Marczylo TH et al. | A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. | 2009 | Anal. Biochem. | pmid:18823934 |
Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
Hong S et al. | Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. | 2009 | Gut | pmid:18936104 |
Correa F et al. | A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. | 2009 | Biochem. Pharmacol. | pmid:18848818 |
Clapper JR et al. | The endocannabinoid system as a target for the treatment of cannabis dependence. | 2009 | Neuropharmacology | pmid:18691603 |
Pasquariello N et al. | Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. | 2009 | J. Biol. Chem. | pmid:19690173 |
Schroeder C et al. | Circulating endocannabinoid concentrations during orthostatic stress. | 2009 | Clin. Auton. Res. | pmid:19756829 |
Catani MV et al. | Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. | 2009 | J. Mol. Med. | pmid:18820887 |
Hill MN et al. | Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. | 2009 | Neuropsychopharmacology | pmid:19710634 |
Yusifzade K et al. | The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. | 2009 | Bratisl Lek Listy | pmid:19711821 |
Thors L and Fowler CJ | Effect of nitric oxide donors on membrane tritium accumulation of endocannabinoids and related endogenous lipids. | 2009 | Eur. J. Pharmacol. | pmid:19715690 |
Kaufmann I et al. | Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report. | 2009 | Eur Surg Res | pmid:19729930 |
Shinohara Y et al. | Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. | 2009 | Neuroreport | pmid:19734811 |
Campos AC and Guimarães FS | Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19735690 |
Wyffels L et al. | Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. | 2009 | J. Med. Chem. | pmid:19719235 |
Di Marzo V et al. | Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. | 2009 | Eur. J. Endocrinol. | pmid:19745037 |
Cano C et al. | Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. | 2009 | Eur J Med Chem | pmid:19762126 |
Centonze D et al. | Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. | 2009 | Neurol. Sci. | pmid:19768368 |
Jean-Gilles L et al. | Plasma endocannabinoid levels in multiple sclerosis. | 2009 | J. Neurol. Sci. | pmid:19695579 |
Wyffels L et al. | Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. | 2009 | Bioorg. Med. Chem. | pmid:19054678 |
Mato S et al. | CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. | 2009 | Glia | pmid:18814177 |