Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Scotchie JG et al. | Endocannabinoid regulation in human endometrium across the menstrual cycle. | 2015 | Reprod Sci | pmid:24819878 |
pmid:24813296 | ||||
Ravi J et al. | FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway. | 2014 | Oncotarget | pmid:24811863 |
Park SW et al. | Anticancer effects of anandamide on head and neck squamous cell carcinoma cells via the production of receptor-independent reactive oxygen species. | 2015 | Head Neck | pmid:24797795 |
pmid:24788457 | ||||
Hama AT et al. | Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain. | 2014 | PLoS ONE | pmid:24788435 |
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pmid:24747871 | ||||
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pmid:24717329 | ||||
Nader J et al. | Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. | 2014 | Neuropharmacology | pmid:24709540 |
pmid:24705535 | ||||
Kaczocha M et al. | Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. | 2014 | PLoS ONE | pmid:24705380 |
Sun LJ et al. | Endocannabinoid system activation contributes to glucose metabolism disorders of hepatocytes and promotes hepatitis C virus replication. | 2014 | Int. J. Infect. Dis. | pmid:24704332 |
Jackson AR et al. | Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. | 2014 | PLoS ONE | pmid:24699635 |
pmid:24687644 | ||||
Baranowska-Kuczko M et al. | Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24682422 |
pmid:24674601 | ||||
pmid:24671517 | ||||
Smaga I et al. | Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures. | 2014 | Neurotox Res | pmid:24652522 |
Basavarajappa BS et al. | Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. | 2014 | Hippocampus | pmid:24648181 |
Yu S et al. | Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in the brain. | 2014 | J. Biol. Chem. | pmid:24644281 |
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Gamage TF et al. | In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. | 2014 | Behav Pharmacol | pmid:24603340 |
Kwilasz AJ et al. | Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. | 2014 | Behav Pharmacol | pmid:24583930 |
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Okura D et al. | The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. | 2014 | Anesth. Analg. | pmid:24557103 |
Sanson B et al. | Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. | 2014 | Acta Crystallogr. D Biol. Crystallogr. | pmid:24531463 |
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Pava MJ et al. | Endocannabinoid modulation of cortical up-states and NREM sleep. | 2014 | PLoS ONE | pmid:24520411 |
Rapino C et al. | Endocannabinoids as biomarkers of human reproduction. | 2014 Jul-Aug | Hum. Reprod. Update | pmid:24516083 |
Zheng Y et al. | Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. | 2014 | Eur. J. Pharmacol. | pmid:24508383 |
pmid:24508153 | ||||
Rea K et al. | Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. | 2014 | Eur. J. Neurosci. | pmid:24494683 |
Sousa-Valente J et al. | Anandamide in primary sensory neurons: too much of a good thing? | 2014 | Eur. J. Neurosci. | pmid:24494681 |
Sagie S et al. | [Short-and long-term effects of cannabinoids on memory, cognition and mental illness]. | 2013 | Harefuah | pmid:24483000 |
Al Kury LT et al. | Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. | 2014 | Cell Calcium | pmid:24472666 |
Björklund E et al. | Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations. | 2014 | PLoS ONE | pmid:24466356 |
Kono M et al. | Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. | 2014 | Bioorg. Med. Chem. | pmid:24440478 |
pmid:24438603 | ||||
Thieme U et al. | Quantification of anandamide and 2-arachidonoylglycerol plasma levels to examine potential influences of tetrahydrocannabinol application on the endocannabinoid system in humans. | 2014 Jan-Feb | Drug Test Anal | pmid:24424856 |
Krishnan G and Chatterjee N | Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity. | 2014 | Mol. Cell. Neurosci. | pmid:24418364 |
Leo LM et al. | Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. | 2014 | PLoS ONE | pmid:24416334 |
Nicolussi S et al. | Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. | 2014 | Pharmacol. Res. | pmid:24412246 |
Mahavadi S et al. | Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24407588 |
Fowler CJ | Has FLAT fallen flat? | 2014 | Trends Pharmacol. Sci. | pmid:24398120 |
Carr RL et al. | Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. | 2014 | Neurotoxicology | pmid:24373905 |
Gesell FK et al. | Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. | 2013 | BMC Vet. Res. | pmid:24370333 |