Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Haller J et al. | The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats. | 2013 | Psychopharmacology (Berl.) | pmid:23743650 |
Andrag E and Curtis MJ | Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids. | 2013 | Br. J. Pharmacol. | pmid:23713981 |
Harvey BS et al. | Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability. | 2013 | Cytokine | pmid:23706402 |
Berge K et al. | Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. | 2013 | Lipids Health Dis | pmid:23706001 |
Amoako AA et al. | Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. | 2013 | Hum. Reprod. | pmid:23697839 |
Ohsaka Y and Nishino H | 3T3-L1 adipocytes possess anandamide- and epinephrine-responsive machinery for MDM2 distribution to the plasma membrane. | 2013 | Gen. Physiol. Biophys. | pmid:23682023 |
Neumeister A et al. | Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study. | 2013 | Mol. Psychiatry | pmid:23670490 |
Lobato NS et al. | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. | 2013 | PLoS ONE | pmid:23667622 |
Li Q et al. | Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. | 2013 | PLoS ONE | pmid:23667607 |
Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
Khasabova IA et al. | Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. | 2013 | Neurobiol. Dis. | pmid:23644187 |
Shinjyo N et al. | Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. | 2013 | J. Neurosci. Res. | pmid:23633391 |
Pryce G et al. | Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. | 2013 | Mult. Scler. | pmid:23625705 |
Abdulnour J et al. | Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study. | 2014 | Obesity (Silver Spring) | pmid:23616305 |
Zhang J et al. | Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. | 2013 | Sheng Li Xue Bao | pmid:23598867 |
Bishay P et al. | Anandamide deficiency and heightened neuropathic pain in aged mice. | 2013 | Neuropharmacology | pmid:23597506 |
Roy A et al. | Stress peptide PACAP engages multiple signaling pathways within the carotid body to initiate excitatory responses in respiratory and sympathetic chemosensory afferents. | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23594614 |
Morgan CJ et al. | Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. | 2013 | Br J Psychiatry | pmid:23580381 |
Descalzi F et al. | Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. | 2013 | Tissue Eng Part A | pmid:23578218 |
Subbanna S et al. | Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. | 2013 | J. Neurosci. | pmid:23575834 |
Starowicz K et al. | Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. | 2013 | PLoS ONE | pmid:23573230 |
Hawkins V and Butt A | TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption. | 2013 | Neurobiol. Dis. | pmid:23567653 |
Seillier A et al. | Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CBâ‚ receptors: implications for schizophrenia. | 2013 | Neuropsychopharmacology | pmid:23563893 |
Bilmin K et al. | Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: implications for the methodology of the MTT tests. | 2013 | Folia Neuropathol | pmid:23553136 |
Gustafsson SB et al. | Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. | 2013 | Arch. Toxicol. | pmid:23552853 |
Blankman JL and Cravatt BF | Chemical probes of endocannabinoid metabolism. | 2013 | Pharmacol. Rev. | pmid:23512546 |
GarcÃa Mdel C et al. | Impaired hypotensive responses induced by intrathecally injected drugs in fructose-fed rats. | 2013 | Eur. J. Pharmacol. | pmid:23499700 |
Fonseca BM et al. | Endogenous cannabinoids revisited: a biochemistry perspective. | 2013 Apr-May | Prostaglandins Other Lipid Mediat. | pmid:23474290 |
Chiurchiù V et al. | Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. | 2013 | Ann. Neurol. | pmid:23447381 |
Fowler CJ | Transport of endocannabinoids across the plasma membrane and within the cell. | 2013 | FEBS J. | pmid:23441874 |
Laezza C et al. | Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. | 2013 | Eur. J. Cancer | pmid:23434151 |
Kapoor S | Modulation of intracellular pathways by anandamide and its evolving role in oncology. | 2013 | Eur. J. Cancer | pmid:23434147 |
Dudášová A et al. | The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. | 2013 | Pulm Pharmacol Ther | pmid:23428645 |
Romano MR and Lograno MD | Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle. | 2013 | Eur. J. Pharmacol. | pmid:23396229 |
Avraham Y et al. | Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). | 2013 | J. Med. Chem. | pmid:23384387 |
Nicotra LL et al. | Prostaglandin ethanolamides attenuate damage in a human explant colitis model. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23380599 |
Compagnucci C et al. | Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. | 2013 | PLoS ONE | pmid:23372698 |
Gebeh AK et al. | Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23372171 |
Li H et al. | Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. | 2013 | Br. J. Pharmacol. | pmid:23347118 |
Zhuang J et al. | The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. | 2013 | AAPS J | pmid:23344792 |
Ho WS | Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase. | 2013 | Eur. J. Pharmacol. | pmid:23340220 |
Romero TR et al. | CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. | 2013 | Anesth. Analg. | pmid:23302980 |
Lenglet S et al. | Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23241405 |
Berger WT et al. | Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. | 2012 | PLoS ONE | pmid:23236415 |
Silva GB et al. | Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23220721 |
Dékány A et al. | The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. | 2013 | Basic Clin. Pharmacol. Toxicol. | pmid:23216932 |
Citraro R et al. | Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. | 2013 | Neuropharmacology | pmid:23206503 |
Fogaça MV et al. | Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. | 2013 | Psychopharmacology (Berl.) | pmid:23183551 |
Buczynski MW et al. | The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. | 2013 | Neuropsychopharmacology | pmid:23169348 |
Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |