Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Sugiura T et al. | Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. | 1999 | J. Biol. Chem. | pmid:9915812 |
Beltramo M and Piomelli D | Anandamide transport inhibition by the vanilloid agonist olvanil. | 1999 | Eur. J. Pharmacol. | pmid:9920187 |
Ng EW et al. | Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. | 1999 | J. Med. Chem. | pmid:10354405 |
Ameri A et al. | Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices. | 1999 | Br. J. Pharmacol. | pmid:10372827 |
Self DW | Anandamide: a candidate neurotransmitter heads for the big leagues. | 1999 | Nat. Neurosci. | pmid:10204533 |
Giuffrida A et al. | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. | 1999 | Nat. Neurosci. | pmid:10204543 |
Paria BC et al. | Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. | 1999 | Biol. Reprod. | pmid:10208977 |
Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
Katayama K et al. | Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme. | 1999 | Biochim. Biophys. Acta | pmid:10521704 |
Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
Leweke FM et al. | Elevated endogenous cannabinoids in schizophrenia. | 1999 | Neuroreport | pmid:10501554 |
Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
Di Marzo V et al. | Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. | 1999 | Curr. Med. Chem. | pmid:10469888 |
Kuwae T et al. | Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. | 1999 | FEBS Lett. | pmid:10508930 |
McAllister SD et al. | Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10525080 |
Yousif MH and Oriowo MA | Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments. | 1999 | Pharmacol. Res. | pmid:10527656 |
Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
Martin BR et al. | Discovery and characterization of endogenous cannabinoids. | 1999 | Life Sci. | pmid:10462059 |
Khanolkar AD and Makriyannis A | Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. | 1999 | Life Sci. | pmid:10462061 |
Howlett AC et al. | Signal transduction of eicosanoid CB1 receptor ligands. | 1999 | Life Sci. | pmid:10462062 |
Di Marzo V | Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. | 1999 | Life Sci. | pmid:10462065 |
Gifford AN et al. | Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). | 1999 | Eur. J. Pharmacol. | pmid:10556675 |
Melck D et al. | Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. | 1999 | FEBS Lett. | pmid:10606728 |
Lagalwar S et al. | Anandamides inhibit binding to the muscarinic acetylcholine receptor. | 1999 Aug-Oct | J. Mol. Neurosci. | pmid:10691292 |
Van den Bossche I and Vanheel B | Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. | 2000 | Br. J. Pharmacol. | pmid:10960073 |
Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
Costa B and Colleoni M | Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. | 2000 | Eur. J. Pharmacol. | pmid:10781666 |
Sarker KP et al. | Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. | 2000 | FEBS Lett. | pmid:10781801 |
Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
Kunos G et al. | Cardiovascular effects of endocannabinoids--the plot thickens. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785543 |
Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
Hillard CJ and Jarrahian A | The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. | 2000 | Chem. Phys. Lipids | pmid:11106786 |
Kunos G et al. | Endocannabinoids as cardiovascular modulators. | 2000 | Chem. Phys. Lipids | pmid:11106789 |
Bisogno T et al. | N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. | 2000 | Biochem. J. | pmid:11042139 |
Wiley JL et al. | Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. | 2000 | Life Sci. | pmid:10983852 |
Stefano GB et al. | 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. | 2000 | Pharmacol. Res. | pmid:10987990 |
Okamoto H et al. | Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. | 2000 | Thromb. Res. | pmid:10942792 |
Martin BR et al. | Cannabinoid properties of methylfluorophosphonate analogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945879 |
Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
Maccarrone M et al. | Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. | 2000 | J. Biol. Chem. | pmid:10913156 |
Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
Muthian S et al. | Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734181 |
Wang Y et al. | Polymyxin B binds to anandamide and inhibits its cytotoxic effect. | 2000 | FEBS Lett. | pmid:10734225 |
Markey SP et al. | Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. | 2000 | J. Lipid Res. | pmid:10744787 |