Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ho WS and Gardiner SM | Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19133994 |
Smart D et al. | 'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism. | 2002 | Br. J. Pharmacol. | pmid:12023948 |
Kirkham TC et al. | Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. | 2002 | Br. J. Pharmacol. | pmid:12055133 |
Ross RA | Anandamide and vanilloid TRPV1 receptors. | 2003 | Br. J. Pharmacol. | pmid:14517174 |
Malinowska B et al. | Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? | 2012 | Br. J. Pharmacol. | pmid:22022923 |
Price TJ et al. | Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. | 2004 | Br. J. Pharmacol. | pmid:15006899 |
Taddei S | Evolving the concept of regulation of vascular tone in humans. | 2005 | Br. J. Pharmacol. | pmid:15997231 |
Mombouli JV et al. | Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. | 1999 | Br. J. Pharmacol. | pmid:10323591 |
Akerman S et al. | Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors. | 2004 | Br. J. Pharmacol. | pmid:15277315 |
Moreno-Sanz G et al. | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. | 2012 | Br. J. Pharmacol. | pmid:22774772 |
Chang L et al. | Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. | 2006 | Br. J. Pharmacol. | pmid:16501580 |
Thors L et al. | Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. | 2007 | Br. J. Pharmacol. | pmid:17676056 |
Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
Pakdeechote P et al. | Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. | 2007 | Br. J. Pharmacol. | pmid:17641668 |
Al Kury LT et al. | Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes. | 2014 | Br. J. Pharmacol. | pmid:24758718 |
Fleming I et al. | Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists. | 1999 | Br. J. Pharmacol. | pmid:10193775 |
Gardiner SM et al. | Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19702785 |
Pertwee RG et al. | Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. | 1993 | Br. J. Pharmacol. | pmid:8306090 |
Evans RM et al. | Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. | 2007 | Br. J. Pharmacol. | pmid:17700720 |
Wheal AJ et al. | Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. | 2007 | Br. J. Pharmacol. | pmid:17700721 |
Matias I et al. | Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. | 2007 | Br. J. Pharmacol. | pmid:17704823 |
Mendiguren A and Pineda J | Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. | 2009 | Br. J. Pharmacol. | pmid:19845674 |
Herradón E et al. | Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta. | 2007 | Br. J. Pharmacol. | pmid:17704831 |
Zakrzeska A et al. | A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. | 2010 | Br. J. Pharmacol. | pmid:20105178 |
Whyte LS et al. | Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro. | 2012 | Br. J. Pharmacol. | pmid:21649637 |
Wheal AJ et al. | Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. | 2010 | Br. J. Pharmacol. | pmid:20590573 |
Gutierrez-Lopez MD et al. | Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. | 2010 | Br. J. Pharmacol. | pmid:20590579 |
Evans RM et al. | Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites. | 2008 | Br. J. Pharmacol. | pmid:18376419 |
Smith PJ and McQueen DS | Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. | 2001 | Br. J. Pharmacol. | pmid:11588121 |
Kawahara H et al. | Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. | 2011 | Br. J. Pharmacol. | pmid:21175570 |
De Petrocellis L et al. | Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. | 2011 | Br. J. Pharmacol. | pmid:21175579 |
Stanford SJ et al. | Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. | 2001 | Br. J. Pharmacol. | pmid:11454655 |
Mang CF et al. | Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors. | 2001 | Br. J. Pharmacol. | pmid:11522608 |
Mechoulam R | Plant cannabinoids: a neglected pharmacological treasure trove. | 2005 | Br. J. Pharmacol. | pmid:16205721 |
Thomas A et al. | Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist. | 2005 | Br. J. Pharmacol. | pmid:16205722 |
Aquila S et al. | Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. | 2010 | Br. J. Pharmacol. | pmid:20067470 |
Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
Bisogno T et al. | Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. | 2001 | Br. J. Pharmacol. | pmid:11606325 |
Li H et al. | Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. | 2013 | Br. J. Pharmacol. | pmid:23347118 |
Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
Evans RM et al. | Multiple actions of anandamide on neonatal rat cultured sensory neurones. | 2004 | Br. J. Pharmacol. | pmid:15023857 |
Stein EA et al. | Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. | 1996 | Br. J. Pharmacol. | pmid:8872363 |
Thors L et al. | Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids. | 2008 | Br. J. Pharmacol. | pmid:18552875 |
Holt S et al. | Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. | 2001 | Br. J. Pharmacol. | pmid:11399668 |
O'Brien LD et al. | Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). | 2013 | Br. J. Pharmacol. | pmid:23991698 |
Lee MG et al. | Effect of olvanil and anandamide on vagal C-fiber subtypes in guinea pig lung. | 2005 | Br. J. Pharmacol. | pmid:16056239 |
Movahed P et al. | Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation. | 2005 | Br. J. Pharmacol. | pmid:15997233 |
Plane F et al. | Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. | 1997 | Br. J. Pharmacol. | pmid:9283682 |
Gaskari SA et al. | Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. | 2005 | Br. J. Pharmacol. | pmid:16025138 |
De Petrocellis L et al. | Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. | 2004 | Br. J. Pharmacol. | pmid:15289293 |