Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Carr RL et al. | Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. | 2014 | Neurotoxicology | pmid:24373905 |
Brantl SA et al. | Mechanism of platelet activation induced by endocannabinoids in blood and plasma. | 2014 | Platelets | pmid:23789792 |
Fonseca BM et al. | Endogenous cannabinoids revisited: a biochemistry perspective. | 2013 Apr-May | Prostaglandins Other Lipid Mediat. | pmid:23474290 |
Dudášová A et al. | The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. | 2013 | Pulm Pharmacol Ther | pmid:23428645 |
Raichlen DA et al. | Exercise-induced endocannabinoid signaling is modulated by intensity. | 2013 | Eur. J. Appl. Physiol. | pmid:22990628 |
Wellner N et al. | N-acylation of phosphatidylethanolamine and its biological functions in mammals. | 2013 | Biochim. Biophys. Acta | pmid:23000428 |
Canseco-Alba A and RodrÃguez-Manzo G | Anandamide transforms noncopulating rats into sexually active animals. | 2013 | J Sex Med | pmid:22906359 |
Vance JE and Tasseva G | Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. | 2013 | Biochim. Biophys. Acta | pmid:22960354 |
Fowler CJ et al. | Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide. | 2013 | J Enzyme Inhib Med Chem | pmid:22225576 |
Martinez-Vargas M et al. | Does the neuroprotective role of anandamide display diurnal variations? | 2013 | Int J Mol Sci | pmid:24287910 |
Gervasi MG et al. | Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle. | 2013 | PLoS ONE | pmid:23977311 |
Zhang J et al. | Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. | 2013 | Sheng Li Xue Bao | pmid:23598867 |
GarcÃa Mdel C et al. | Impaired hypotensive responses induced by intrathecally injected drugs in fructose-fed rats. | 2013 | Eur. J. Pharmacol. | pmid:23499700 |
Kim HY and Spector AA | Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22959887 |
Iannotti FA et al. | Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23830028 |
Ruginsk SG et al. | Anandamide modulates the neuroendocrine responses induced by extracellular volume expansion. | 2013 | Clin. Exp. Pharmacol. Physiol. | pmid:23875874 |
Silvestri C et al. | Anandamide-derived prostamide F2α negatively regulates adipogenesis. | 2013 | J. Biol. Chem. | pmid:23801328 |
Pryce G et al. | Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. | 2013 | Mult. Scler. | pmid:23625705 |
Amoako AA et al. | Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. | 2013 | Hum. Reprod. | pmid:23697839 |
Ohsaka Y and Nishino H | 3T3-L1 adipocytes possess anandamide- and epinephrine-responsive machinery for MDM2 distribution to the plasma membrane. | 2013 | Gen. Physiol. Biophys. | pmid:23682023 |
Roy A et al. | Stress peptide PACAP engages multiple signaling pathways within the carotid body to initiate excitatory responses in respiratory and sympathetic chemosensory afferents. | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23594614 |
Bishay P et al. | Anandamide deficiency and heightened neuropathic pain in aged mice. | 2013 | Neuropharmacology | pmid:23597506 |
Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
Oh HA et al. | Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos. | 2013 | Mol. Hum. Reprod. | pmid:23112252 |
Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |
Abán C et al. | Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis. | 2013 | Placenta | pmid:23122699 |
Romero TR et al. | Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors. | 2013 | Life Sci. | pmid:23123446 |
Guindon J et al. | Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. | 2013 | Pharmacol. Res. | pmid:23127915 |
Buczynski MW et al. | The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. | 2013 | Neuropsychopharmacology | pmid:23169348 |
Lee TT et al. | Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. | 2013 | Synapse | pmid:22987804 |
Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Pedroza-Llinás R et al. | CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning. | 2013 | Behav. Brain Res. | pmid:23018128 |
Harvey BS et al. | Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability. | 2013 | Cytokine | pmid:23706402 |
Carr RL et al. | Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. | 2013 | Toxicol. Sci. | pmid:23761300 |
Andrag E and Curtis MJ | Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids. | 2013 | Br. J. Pharmacol. | pmid:23713981 |
Fogaça MV et al. | Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. | 2013 | Psychopharmacology (Berl.) | pmid:23183551 |
De-May CL and Ali AB | Cell type-specific regulation of inhibition via cannabinoid type 1 receptors in rat neocortex. | 2013 | J. Neurophysiol. | pmid:23054605 |
Coppola M and Mondola R | Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. | 2013 | Med. Hypotheses | pmid:23896215 |
Lisboa SF et al. | Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. | 2013 | Neuropharmacology | pmid:23899460 |
Ilayan E et al. | Do cannabinoids exhibit a tyramine-like effect? | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23900610 |
Derbenev AV and Smith BN | Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. | 2013 | PLoS ONE | pmid:23936221 |
Krumbholz A et al. | Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. | 2013 | Ther Drug Monit | pmid:23942543 |
Liu J et al. | Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24191036 |
Hill MN et al. | Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. | 2013 | Psychoneuroendocrinology | pmid:24035186 |
Khasabova IA et al. | Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. | 2013 | Neurobiol. Dis. | pmid:23644187 |
Gesell FK et al. | Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. | 2013 | BMC Vet. Res. | pmid:24370333 |
Sagie S et al. | [Short-and long-term effects of cannabinoids on memory, cognition and mental illness]. | 2013 | Harefuah | pmid:24483000 |
Nicotra LL et al. | Prostaglandin ethanolamides attenuate damage in a human explant colitis model. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23380599 |
Shinjyo N et al. | Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. | 2013 | J. Neurosci. Res. | pmid:23633391 |
Gustafsson SB et al. | Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. | 2013 | Arch. Toxicol. | pmid:23552853 |