Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Davies JW et al. | Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population. | 2010 | Br J Anaesth | pmid:20354008 |
Morera-Herreras T et al. | Regulation of subthalamic neuron activity by endocannabinoids. | 2010 | Synapse | pmid:20336631 |
Falenski KW et al. | FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. | 2010 | Neuropsychopharmacology | pmid:20357755 |
Wu WJ et al. | [Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells]. | 2010 | Zhonghua Gan Zang Bing Za Zhi | pmid:20380798 |
Hoot MR et al. | Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. | 2010 | Brain Res. | pmid:20380816 |
Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
Nallendran V et al. | The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour. | 2010 | BJOG | pmid:20406230 |
Kobayashi N and Yamamoto Y | Hypoxic responses of arterial chemoreceptors in rabbits are primarily mediated by leak K channels. | 2010 | Adv. Exp. Med. Biol. | pmid:20217348 |
Tree K et al. | Anandamide centrally depresses the respiratory rhythm generator of neonatal mice. | 2010 | Neuroscience | pmid:20800658 |
Glaser ST and Kaczocha M | Cyclooxygenase-2 mediates anandamide metabolism in the mouse brain. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20702753 |
Pratt-Hyatt M et al. | Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide. | 2010 | Drug Metab. Dispos. | pmid:20702771 |
Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
Jiang S et al. | Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. | 2010 | J. Biol. Chem. | pmid:20826813 |
Linsalata M et al. | Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. | 2010 | Anticancer Res. | pmid:20682986 |
Osman NA et al. | Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. | 2010 | Bioorg. Med. Chem. | pmid:21074998 |
Catani MV et al. | Anandamide extends platelets survival through CB(1)-dependent Akt signaling. | 2010 | Cell. Mol. Life Sci. | pmid:19936621 |
Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
Oddi S et al. | Pitfalls and solutions in assaying anandamide transport in cells. | 2010 | J. Lipid Res. | pmid:20447929 |
Pisani V et al. | Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients. | 2010 | Mov. Disord. | pmid:20461809 |
Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
Naccarato M et al. | Possible Anandamide and Palmitoylethanolamide involvement in human stroke. | 2010 | Lipids Health Dis | pmid:20470384 |
Muccioli GG | Endocannabinoid biosynthesis and inactivation, from simple to complex. | 2010 | Drug Discov. Today | pmid:20304091 |
Laezza C et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells. | 2010 | Endocr. Relat. Cancer | pmid:20304978 |
Makwana R et al. | Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation. | 2010 | Br. J. Pharmacol. | pmid:20233228 |
Kozono S et al. | Involvement of the endocannabinoid system in periodontal healing. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20233580 |
Rueda-Orozco PE et al. | Intrahippocampal administration of anandamide increases REM sleep. | 2010 | Neurosci. Lett. | pmid:20188142 |
Onnis V et al. | Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. | 2010 | J. Med. Chem. | pmid:20143779 |
Bhaskaran MD and Smith BN | Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy. | 2010 | Exp. Neurol. | pmid:20144892 |
Alptekin A et al. | The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels. | 2010 | Eur. J. Pharmacol. | pmid:20171208 |
Snider NT et al. | Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications. | 2010 | Pharmacol. Rev. | pmid:20133390 |
Moreno-Galindo EG et al. | Molecular basis for a high-potency open-channel block of Kv1.5 channel by the endocannabinoid anandamide. | 2010 | Mol. Pharmacol. | pmid:20133392 |
Weis F et al. | Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. | 2010 | J. Mol. Cell. Cardiol. | pmid:19931541 |
Pamplona FA et al. | Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice. | 2010 | Neurosci. Lett. | pmid:20036315 |
Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. | 2010 | Cardiovasc. Res. | pmid:19942623 |
Prestifilippo JP et al. | Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. | 2009 Sep-Oct | Alcohol Alcohol. | pmid:19589828 |
Marco EM et al. | Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. | 2009 | Brain Res. | pmid:19133243 |
Ho WS and Gardiner SM | Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19133994 |
Ferreira SG et al. | N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. | 2009 | Neuropharmacology | pmid:19101577 |
Ozalp A and Barroso B | Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. | 2009 | Anal. Biochem. | pmid:19665986 |
Dowie MJ et al. | Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. | 2009 | Neuroscience | pmid:19524019 |
Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
Maeda N et al. | Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. | 2009 | Fundam Clin Pharmacol | pmid:19527302 |
Straiker A and Mackie K | Cannabinoid signaling in inhibitory autaptic hippocampal neurons. | 2009 | Neuroscience | pmid:19501632 |
Kinsey SG et al. | Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19502530 |
Brighton PJ et al. | Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. | 2009 | Mol. Endocrinol. | pmid:19477951 |
Oddi S et al. | Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. | 2009 | Chem. Biol. | pmid:19481477 |
Reis GM et al. | Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. | 2009 | Life Sci. | pmid:19576231 |
Umathe SN et al. | Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19580839 |
Murakami T et al. | Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. | 2009 | Int. Immunol. | pmid:19556302 |
Palandra J et al. | Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19535304 |
Snider NT et al. | A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. | 2009 | Mol. Pharmacol. | pmid:19171674 |
Alpini G and Demorrow S | Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. | 2009 | Vitam. Horm. | pmid:19647123 |
Astarita G et al. | Targeted lipidomics as a tool to investigate endocannabinoid function. | 2009 | Int. Rev. Neurobiol. | pmid:19607960 |
Francavilla F et al. | Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. | 2009 | Endocrinology | pmid:19608651 |
Centonze D et al. | Altered anandamide degradation in attention-deficit/hyperactivity disorder. | 2009 | Neurology | pmid:19398708 |
Liu H et al. | Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. | 2009 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:19399401 |
Mazzola C et al. | Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. | 2009 | Learn. Mem. | pmid:19403796 |
Shen Y et al. | A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. | 2009 | J. Neurosci. | pmid:19439586 |
Ahn K et al. | Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. | 2009 | Chem. Biol. | pmid:19389627 |
Yates ML and Barker EL | Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. | 2009 | Mol. Pharmacol. | pmid:19389920 |
Miyato H et al. | Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. | 2009 | J. Surg. Res. | pmid:19394652 |
Balas L et al. | Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. | 2009 | J. Med. Chem. | pmid:19161308 |
Carney ST et al. | Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. | 2009 | J Neuroimmune Pharmacol | pmid:19365734 |
Gardiner SM et al. | Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19702785 |
Guindon J and Hohmann AG | The endocannabinoid system and pain. | 2009 | CNS Neurol Disord Drug Targets | pmid:19839937 |
Karaliota S et al. | Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. | 2009 | Obesity (Silver Spring) | pmid:19543211 |
Marco EM and Viveros MP | The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. | 2009 | Mini Rev Med Chem | pmid:19929814 |
Vercelli CA et al. | Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. | 2009 | Placenta | pmid:19428101 |
Mendiguren A and Pineda J | Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. | 2009 | Br. J. Pharmacol. | pmid:19845674 |
Bradshaw HB et al. | The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. | 2009 | BMC Biochem. | pmid:19460156 |
Li Q et al. | Electrophysiological effects of anandamide on rat myocardium. | 2009 | Br. J. Pharmacol. | pmid:20050190 |
Hiley CR | Endocannabinoids and the heart. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19276990 |
Gratzke C et al. | Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. | 2009 | J. Urol. | pmid:19237169 |
El-Talatini MR et al. | Localisation and function of the endocannabinoid system in the human ovary. | 2009 | PLoS ONE | pmid:19238202 |
Parker LA et al. | The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). | 2009 | Physiol. Behav. | pmid:19239915 |
Schlosburg JE et al. | Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. | 2009 | AAPS J | pmid:19184452 |
Navarrete CM et al. | Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. | 2009 | J. Neurochem. | pmid:19200337 |
Tang B et al. | Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19188660 |
Ribeiro ML et al. | 17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. | 2009 | Reprod. Biomed. Online | pmid:19192341 |
McMahon LR | Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. | 2009 | Psychopharmacology (Berl.) | pmid:18592221 |
McCue JM et al. | In vitro synthesis of arachidonoyl amino acids by cytochrome c. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19683594 |
El-Talatini MR et al. | Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. | 2009 | Hum. Reprod. | pmid:19363040 |
Brizzi A et al. | New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. | 2009 | J. Med. Chem. | pmid:19331413 |
Koethe D et al. | Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. | 2009 | Br J Psychiatry | pmid:19336792 |
Mangieri RA et al. | An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | 2009 | Psychopharmacology (Berl.) | pmid:19343330 |
Potenzieri C et al. | Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. | 2009 | Brain Res. | pmid:19285051 |
De Petrocellis L and Di Marzo V | An introduction to the endocannabinoid system: from the early to the latest concepts. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285257 |
Borrelli F and Izzo AA | Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285259 |
Bermúdez-Silva FJ et al. | The role of the pancreatic endocannabinoid system in glucose metabolism. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285263 |
Kaczocha M et al. | Identification of intracellular carriers for the endocannabinoid anandamide. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19307565 |
Alenmyr L et al. | TRPV1-mediated itch in seasonal allergic rhinitis. | 2009 | Allergy | pmid:19220220 |
GarcÃa-GarcÃa F et al. | Sleep-inducing factors. | 2009 | CNS Neurol Disord Drug Targets | pmid:19689305 |
Tuboly G et al. | The antinociceptive interaction of anandamide and adenosine at the spinal level. | 2009 | Pharmacol. Biochem. Behav. | pmid:18760296 |
Tuboly G et al. | Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. | 2009 | Clin. Exp. Pharmacol. Physiol. | pmid:19018802 |
Schacht JP et al. | Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. | 2009 | Psychopharmacology (Berl.) | pmid:19002671 |
Araújo JR et al. | Effect of cannabinoids upon the uptake of folic acid by BeWo cells. | 2009 | Pharmacology | pmid:19145103 |
Van Dross RT | Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. | 2009 | Mol. Carcinog. | pmid:19148897 |
Hydock DS et al. | Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. | 2009 | J. Cardiovasc. Pharmacol. Ther. | pmid:19129423 |
Lin YS et al. | Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. | 2009 | J. Appl. Physiol. | pmid:19131477 |