Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zenor BN et al. | Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. | 1999 | Life Sci. | pmid:10416818 |
Sugiura T et al. | Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. | 1999 | J. Biol. Chem. | pmid:9915812 |
Beltramo M and Piomelli D | Anandamide transport inhibition by the vanilloid agonist olvanil. | 1999 | Eur. J. Pharmacol. | pmid:9920187 |
Chaytor AT et al. | The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. | 1999 | J. Physiol. (Lond.) | pmid:10523421 |
Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
Mombouli JV et al. | Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. | 1999 | Br. J. Pharmacol. | pmid:10323591 |
Watanabe K et al. | Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. | 1999 | Biol. Pharm. Bull. | pmid:10328555 |
Mechoulam R and Ben-Shabat S | From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. | 1999 | Nat Prod Rep | pmid:10331283 |
Burstein SH | The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential. | 1999 | Pharmacol. Ther. | pmid:10341359 |
Di Marzo V et al. | Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. | 1999 | Lipids | pmid:10419192 |
Hansen HS et al. | Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. | 1999 | Lipids | pmid:10419193 |
Kiss Z | Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts. | 1999 | FEBS Lett. | pmid:10214947 |
Maccarrone M et al. | Anandamide activates human platelets through a pathway independent of the arachidonate cascade. | 1999 | FEBS Lett. | pmid:10214961 |
Yang HY et al. | GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat. | 1999 | J. Neurochem. | pmid:10217273 |
Raffa RB et al. | Differential cholera-toxin sensitivity of supraspinal antinociception induced by the cannabinoid agonists delta9-THC, WIN 55,212-2 and anandamide in mice. | 1999 | Neurosci. Lett. | pmid:10218903 |
De Petrocellis L et al. | Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. | 1999 | Neuroscience | pmid:10392859 |
Williams CM and Kirkham TC | Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. | 1999 | Psychopharmacology (Berl.) | pmid:10353436 |
Fimiani C et al. | Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. | 1999 | Cell. Signal. | pmid:10353693 |
Ng EW et al. | Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. | 1999 | J. Med. Chem. | pmid:10354405 |
Ameri A et al. | Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices. | 1999 | Br. J. Pharmacol. | pmid:10372827 |
Self DW | Anandamide: a candidate neurotransmitter heads for the big leagues. | 1999 | Nat. Neurosci. | pmid:10204533 |
Giuffrida A et al. | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. | 1999 | Nat. Neurosci. | pmid:10204543 |
Paria BC et al. | Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. | 1999 | Biol. Reprod. | pmid:10208977 |
Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
Sagan S et al. | Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. | 1999 | Eur. J. Neurosci. | pmid:10051770 |
Kobayashi H et al. | Recent progress in the neurotoxicology of natural drugs associated with dependence or addiction, their endogenous agonists and receptors. | 1999 | J Toxicol Sci | pmid:10073332 |
Bisogno T et al. | Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10079192 |
Fleming I et al. | Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists. | 1999 | Br. J. Pharmacol. | pmid:10193775 |
Hohmann AG et al. | Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. | 1999 | Brain Res. | pmid:10082879 |
Wang J et al. | Stage-specific excitation of cannabinoid receptor exhibits differential effects on mouse embryonic development. | 1999 | Biol. Reprod. | pmid:10084956 |
Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
Katayama K et al. | Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme. | 1999 | Biochim. Biophys. Acta | pmid:10521704 |
Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
Leweke FM et al. | Elevated endogenous cannabinoids in schizophrenia. | 1999 | Neuroreport | pmid:10501554 |
Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
Di Marzo V et al. | Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. | 1999 | Curr. Med. Chem. | pmid:10469888 |
Kuwae T et al. | Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. | 1999 | FEBS Lett. | pmid:10508930 |
McAllister SD et al. | Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10525080 |
Yousif MH and Oriowo MA | Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments. | 1999 | Pharmacol. Res. | pmid:10527656 |
Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
Martin BR et al. | Discovery and characterization of endogenous cannabinoids. | 1999 | Life Sci. | pmid:10462059 |
Khanolkar AD and Makriyannis A | Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. | 1999 | Life Sci. | pmid:10462061 |
Howlett AC et al. | Signal transduction of eicosanoid CB1 receptor ligands. | 1999 | Life Sci. | pmid:10462062 |
Di Marzo V | Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. | 1999 | Life Sci. | pmid:10462065 |
Ueda N et al. | An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors. | 1999 | FEBS Lett. | pmid:10431820 |
Fowler CJ et al. | Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. | 1999 | Arch. Biochem. Biophys. | pmid:9989926 |
Basavarajappa BS and Hungund BL | Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. | 1999 | J. Neurochem. | pmid:9930723 |
Wagner JA et al. | Mesenteric vasodilation mediated by endothelial anandamide receptors. | 1999 | Hypertension | pmid:9931142 |
Goparaju SK et al. | Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. | 1999 | Biochem. Pharmacol. | pmid:9933030 |
Gifford AN et al. | Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). | 1999 | Eur. J. Pharmacol. | pmid:10556675 |
Melck D et al. | Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. | 1999 | FEBS Lett. | pmid:10606728 |
Castellano C et al. | Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. | 1999 | Behav Pharmacol | pmid:10780251 |
González S et al. | Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. | 1999 | Life Sci. | pmid:10447218 |
Gebremedhin D et al. | Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. | 1999 | Am. J. Physiol. | pmid:10362691 |
Melck D et al. | Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10448105 |
Lang W et al. | Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase. | 1999 | J. Med. Chem. | pmid:10072686 |
Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |
Childers SR and Breivogel CS | Cannabis and endogenous cannabinoid systems. | 1998 Jun-Jul | Drug Alcohol Depend | pmid:9716939 |
Brăiloiu C et al. | [Endothelium-derived hyperpolarizing factor]. | 1998 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756843 |
McGregor IS et al. | A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. | 1998 | Brain Res. | pmid:9748483 |
Schneider U et al. | Cannabinoid/anandamide system and schizophrenia: is there evidence for association? | 1998 | Pharmacopsychiatry | pmid:9754842 |
Stengel PW et al. | Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. | 1998 | Eur. J. Pharmacol. | pmid:9754939 |
Pestonjamasp VK and Burstein SH | Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. | 1998 | Biochim. Biophys. Acta | pmid:9795237 |
White R and Hiley CR | The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. | 1998 | Br. J. Pharmacol. | pmid:9806337 |
Levin M and Mercola M | Gap junctions are involved in the early generation of left-right asymmetry. | 1998 | Dev. Biol. | pmid:9806775 |
Aceto MD et al. | Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808686 |
Murillo-RodrÃguez E et al. | Anandamide modulates sleep and memory in rats. | 1998 | Brain Res. | pmid:9813364 |
Jaggar SI et al. | The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. | 1998 | Neurosci. Lett. | pmid:9774165 |
Fulton D and Quilley J | Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732371 |
Welch SP et al. | Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732392 |
Fields HL and Meng ID | Watching the pot boil. | 1998 | Nat. Med. | pmid:9734389 |
Pate DW et al. | Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. | 1998 | Life Sci. | pmid:9851310 |
Molina-Holgado F et al. | The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. | 1998 | FEBS Lett. | pmid:9738948 |
Patel NA et al. | Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. | 1998 | Brain Res. | pmid:9666136 |
Calignano A et al. | Control of pain initiation by endogenous cannabinoids. | 1998 | Nature | pmid:9685157 |
Stefano GB et al. | Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. | 1998 | Int. J. Cardiol. | pmid:9687087 |
Stefano GB | Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release. | 1998 | J. Neuroimmunol. | pmid:9610675 |
Smith FL et al. | Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. | 1998 | Pharmacol. Biochem. Behav. | pmid:9610941 |
Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
Prevot V et al. | Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. | 1998 | Brain Res. | pmid:9593913 |
Di Marzo V | 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. | 1998 | Biochim. Biophys. Acta | pmid:9630590 |
Stefano GB et al. | Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. | 1998 | Brain Res. | pmid:9630717 |
Schmid PC et al. | Alternative pathways of anandamide biosynthesis in rat testes. | 1998 | Chem. Phys. Lipids | pmid:9631536 |
Varga K et al. | Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. | 1998 | FASEB J. | pmid:9707176 |
Mallet PE and Beninger RJ | Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. | 1998 | Life Sci. | pmid:9651110 |
Qin C et al. | Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. | 1998 | Anal. Biochem. | pmid:9683506 |
De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |
Chakrabarti A et al. | Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. | 1998 | Brain Res. Bull. | pmid:9434204 |
Lin S et al. | Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. | 1998 | J. Med. Chem. | pmid:9876105 |
van Zadelhoff G et al. | With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675081 |
Di Marzo V et al. | The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. | 1998 | Biochem. J. | pmid:9512456 |
Adams IB et al. | Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9495885 |
Giuffrida A and Piomelli D | Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. | 1998 | FEBS Lett. | pmid:9498819 |
Goparaju SK et al. | Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. | 1998 | FEBS Lett. | pmid:9475172 |
Sulcova E et al. | Biphasic effects of anandamide. | 1998 | Pharmacol. Biochem. Behav. | pmid:9476980 |
Kimura T et al. | Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. | 1998 | Biol. Pharm. Bull. | pmid:9556149 |
Qureshi J et al. | Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. | 1998 | Mol. Cell. Biochem. | pmid:9562238 |
Paria BC et al. | Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. | 1998 | Biol. Reprod. | pmid:9623610 |
Richardson JD et al. | Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. | 1998 | Pain | pmid:9539680 |