Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Panagis G et al. | Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. | 2008 | Curr Drug Abuse Rev | pmid:19630731 |
Xiong W et al. | Anandamide inhibition of 5-HT3A receptors varies with receptor density and desensitization. | 2008 | Mol. Pharmacol. | pmid:17993512 |
Hill MN et al. | Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. | 2008 | Hippocampus | pmid:18058925 |
Rueda-Orozco PE et al. | A potential function of endocannabinoids in the selection of a navigation strategy by rats. | 2008 | Psychopharmacology (Berl.) | pmid:17805517 |
Wise LE et al. | Evaluation of fatty acid amides in the carrageenan-induced paw edema model. | 2008 | Neuropharmacology | pmid:17675189 |
Murillo-RodrÃguez E et al. | The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. | 2008 | Neuroscience | pmid:18822353 |
Woo DH et al. | Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). | 2008 | Mol Pain | pmid:18826653 |
Currie S et al. | IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. | 2008 | J. Mol. Cell. Cardiol. | pmid:18692061 |
Turco MY et al. | High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferation. | 2008 | Hum. Reprod. | pmid:18614613 |
Maccarrone M | Anandamide as a marker of human disease. | 2008 | JAMA | pmid:18632539 |
Williams MA et al. | The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathyic rats: evidence at the cannabinoid CB1 receptor. | 2008 | J. Physiol. (Lond.) | pmid:18063665 |
Justinova Z et al. | Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. | 2008 | Biol. Psychiatry | pmid:18814866 |
Correa F et al. | Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2). | 2008 | Biochem. J. | pmid:17961121 |
Taylor AH et al. | The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy. | 2007 Sep-Oct | Hum. Reprod. Update | pmid:17584820 |
Sakamoto Y et al. | Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. | 2007 Sep-Oct | ASAIO J. | pmid:17885340 |
D'Argenio G et al. | Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. | 2007 | J. Mol. Med. | pmid:17396241 |
Holt S et al. | Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. | 2007 | Eur. J. Pharmacol. | pmid:17397826 |
Mahler SV et al. | Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. | 2007 | Neuropsychopharmacology | pmid:17406653 |
Kopczyńska B | The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. | 2007 | Life Sci. | pmid:17379256 |
Ferrer B et al. | Regulation of brain anandamide by acute administration of ethanol. | 2007 | Biochem. J. | pmid:17302558 |
Naidu PS et al. | Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. | 2007 | Psychopharmacology (Berl.) | pmid:17279376 |
Sun Y et al. | Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. | 2007 | Br. J. Pharmacol. | pmid:17906680 |
Rubio M et al. | Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol. | 2007 | Neurosci. Lett. | pmid:17574742 |
Ryberg E et al. | The orphan receptor GPR55 is a novel cannabinoid receptor. | 2007 | Br. J. Pharmacol. | pmid:17876302 |
Ghasemi M et al. | Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. | 2007 | Br. J. Pharmacol. | pmid:17486141 |
Borsani E et al. | AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. | 2007 | Brain Res. | pmid:17459353 |
Sit SY et al. | Novel inhibitors of fatty acid amide hydrolase. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17459705 |
Lory P and Chemin J | Towards the discovery of novel T-type calcium channel blockers. | 2007 | Expert Opin. Ther. Targets | pmid:17465728 |
Ryan D et al. | Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. | 2007 | Eur. J. Neurosci. | pmid:17419758 |
Gonthier MP et al. | Identification of endocannabinoids and related compounds in human fat cells. | 2007 | Obesity (Silver Spring) | pmid:17426318 |
Raduner S et al. | Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides. | 2007 | J. Nat. Prod. | pmid:17497806 |
Wang Y and Wang DH | Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. | 2007 | Cardiovasc Hematol Disord Drug Targets | pmid:17346127 |
Béquet F et al. | CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. | 2007 | Eur. J. Neurosci. | pmid:18052990 |
Rettori V et al. | Endocannabinoids in TNF-alpha and ethanol actions. | 2007 | Neuroimmunomodulation | pmid:18073513 |
Rossi G et al. | Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. | 2007 | Endocrinology | pmid:17110429 |
Cross-Mellor SK et al. | Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. | 2007 | Psychopharmacology (Berl.) | pmid:17111174 |
Ronco AM et al. | Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. | 2007 | Pharmacology | pmid:17114903 |
Ho WS and Randall MD | Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. | 2007 | Br. J. Pharmacol. | pmid:17245358 |
Wheal AJ et al. | Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. | 2007 | Br. J. Pharmacol. | pmid:17245361 |
Romero FA et al. | Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. | 2007 | J. Med. Chem. | pmid:17279740 |
Wang Y et al. | Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17308041 |
Snider NT et al. | Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17272674 |
Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
Solinas M et al. | The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17210800 |
Hsu SS et al. | Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. | 2007 | Toxicology | pmid:17222495 |
Harada N and Okajima K | Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. | 2007 | Dig. Dis. Sci. | pmid:17211693 |
Pisanti S et al. | Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. | 2007 | J. Cell. Physiol. | pmid:17192847 |
Ekins S et al. | Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | 2007 | Drug Metab. Dispos. | pmid:17194716 |
Schreiber D et al. | Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. | 2007 | Anal. Biochem. | pmid:17196922 |
Kreutz S et al. | Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. | 2007 | Exp. Neurol. | pmid:17010339 |