Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Katona I and Freund TF | Multiple functions of endocannabinoid signaling in the brain. | 2012 | Annu. Rev. Neurosci. | pmid:22524785 |
Tong S et al. | Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. | 2012 | Obstet Gynecol | pmid:22525911 |
Gould GG et al. | Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. | 2012 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:22542870 |
Sordelli MS et al. | Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. | 2012 | Eur. J. Pharmacol. | pmid:22554772 |
Haruta C | [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. | 2012 | Kokubyo Gakkai Zasshi | pmid:22568077 |
Khasabova IA et al. | Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. | 2012 | J. Neurosci. | pmid:22593077 |
Okine BN et al. | Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. | 2012 | Br. J. Pharmacol. | pmid:22595021 |
Miyashita K et al. | Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture. | 2012 | J Endod | pmid:22595113 |
Vinod KY et al. | Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. | 2012 | PLoS ONE | pmid:22606285 |
Baranowska-Kuczko M et al. | Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. | 2012 | Pharmacol. Res. | pmid:22627170 |
Chicca A et al. | The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. | 2012 | Br. J. Pharmacol. | pmid:22646533 |
Hernangómez M et al. | CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. | 2012 | Glia | pmid:22653796 |
Tsumura M et al. | TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. | 2012 | Cell Calcium | pmid:22656960 |
Chianese R et al. | Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22669247 |
Lipina C et al. | New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. | 2012 | Bioessays | pmid:22674489 |
Forsell PK et al. | Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. | 2012 | Lipids | pmid:22684912 |
Ritter JK et al. | Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22685343 |
Gunduz-Cinar O et al. | Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. | 2013 | Mol. Psychiatry | pmid:22688188 |
Gebeh AK et al. | Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22701012 |
Leweke FM | Anandamide dysfunction in prodromal and established psychosis. | 2012 | Curr. Pharm. Des. | pmid:22716147 |
Wang ZJ et al. | Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. | 2012 | J. Neurosci. | pmid:22723687 |
Neelamegan D et al. | Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. | 2012 | BMC Microbiol. | pmid:22730904 |
Moreno-Sanz G et al. | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. | 2012 | Br. J. Pharmacol. | pmid:22774772 |
Rettori E et al. | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. | 2012 | Neuroimmunomodulation | pmid:22777139 |
Luchicchi A and Pistis M | Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids. | 2012 | Mol. Neurobiol. | pmid:22801993 |
Camann DE et al. | Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure. | 2013 | J Expo Sci Environ Epidemiol | pmid:22805989 |
Krishnan G and Chatterjee N | Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation. | 2012 | Glia | pmid:22807196 |
Willibald J et al. | Click-modified anandamide siRNA enables delivery and gene silencing in neuronal and immune cells. | 2012 | J. Am. Chem. Soc. | pmid:22812910 |
Stock K et al. | Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. | 2012 | Nat. Med. | pmid:22820645 |
Leweke FM et al. | Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | 2012 | Transl Psychiatry | pmid:22832859 |
Lara-Celador I et al. | Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats. | 2012 | Brain Res. | pmid:22841538 |
Kaczocha M et al. | Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. | 2012 | ACS Chem Neurosci | pmid:22860204 |
De Petrocellis L et al. | A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. | 2012 | Br. J. Pharmacol. | pmid:22861649 |
Chicca A et al. | Evidence for bidirectional endocannabinoid transport across cell membranes. | 2012 | J. Biol. Chem. | pmid:22879589 |
Tanveer R et al. | The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. | 2012 | J. Biol. Chem. | pmid:22891244 |
Canseco-Alba A and RodrÃguez-Manzo G | Anandamide transforms noncopulating rats into sexually active animals. | 2013 | J Sex Med | pmid:22906359 |
Brown WH et al. | Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22912404 |
Alhouayek M and Muccioli GG | The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. | 2012 | Trends Mol Med | pmid:22917662 |
Sanchez AM et al. | The molecular connections between the cannabinoid system and endometriosis. | 2012 | Mol. Hum. Reprod. | pmid:22923487 |
Woodhams SG et al. | Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. | 2012 | Br. J. Pharmacol. | pmid:22924700 |
Lowin T et al. | Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system. | 2012 | Arthritis Rheum. | pmid:22933357 |
Rogers TJ | The molecular basis for neuroimmune receptor signaling. | 2012 | J Neuroimmune Pharmacol | pmid:22935971 |
Chon SH et al. | Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. | 2012 | PLoS ONE | pmid:22937137 |
Kim HY and Spector AA | Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22959887 |
Schreiber AK et al. | Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. | 2012 | Neuropharmacology | pmid:22959964 |
Vance JE and Tasseva G | Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. | 2013 | Biochim. Biophys. Acta | pmid:22960354 |
Lee TT et al. | Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. | 2013 | Synapse | pmid:22987804 |
Raichlen DA et al. | Exercise-induced endocannabinoid signaling is modulated by intensity. | 2013 | Eur. J. Appl. Physiol. | pmid:22990628 |
Wellner N et al. | N-acylation of phosphatidylethanolamine and its biological functions in mammals. | 2013 | Biochim. Biophys. Acta | pmid:23000428 |
Hauer D et al. | Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression. | 2012 | Rev Neurosci | pmid:23006898 |