Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vanheel B and Van de Voorde J | Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11160613 |
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Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
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Kurihara J et al. | 2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves. | 2001 | Jpn. J. Pharmacol. | pmid:11676206 |
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Jamshidi N and Taylor DA | Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. | 2001 | Br. J. Pharmacol. | pmid:11704633 |
Gurwitz D and Weizman A | Fatty acid amide hydrolase inhibitors and the marijuana debate. | 2001 | Lancet | pmid:11705595 |
Rice AS | Cannabinoids and pain. | 2001 | Curr Opin Investig Drugs | pmid:11575713 |
Karava V et al. | Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. | 2001 | FEBS Lett. | pmid:11728445 |
Berger A et al. | Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11353819 |
Craib SJ et al. | A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. | 2001 | Br. J. Pharmacol. | pmid:11522594 |
Deutsch DG et al. | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. | 2001 | J. Biol. Chem. | pmid:11118429 |
Garcia N et al. | Systemic and portal hemodynamic effects of anandamide. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11123193 |
Al-Hayani A et al. | The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. | 2001 | Neuropharmacology | pmid:11747904 |
Izzo AA et al. | The gastrointestinal pharmacology of cannabinoids. | 2001 | Curr Opin Pharmacol | pmid:11757815 |
Wagner JA et al. | Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. | 2001 | J. Am. Coll. Cardiol. | pmid:11738314 |
Huang SM et al. | Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. | 2001 | J. Biol. Chem. | pmid:11518719 |
López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. | 2001 | J. Med. Chem. | pmid:11741470 |
Jacobsson SO and Fowler CJ | Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. | 2001 | Br. J. Pharmacol. | pmid:11309246 |
Quistad GB et al. | Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11350214 |
Day TA et al. | Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. | 2001 | Mol. Pharmacol. | pmid:11353795 |
Kobayashi Y et al. | Activation by 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, of p42/44 mitogen-activated protein kinase in HL-60 cells. | 2001 | J. Biochem. | pmid:11328586 |
Chang YH et al. | Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. | 2001 | J. Cell. Biochem. | pmid:11329626 |
Olah Z et al. | Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. | 2001 | J. Biol. Chem. | pmid:11333266 |
Calignano A et al. | Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. | 2001 | Eur. J. Pharmacol. | pmid:11426841 |
Fride E et al. | Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. | 2001 | Eur. J. Pharmacol. | pmid:11426843 |
Ugdyzhekova DS et al. | Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. | 2001 | Bull. Exp. Biol. Med. | pmid:11427912 |
Di Marzo V et al. | Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. | 2001 | Biochem. J. | pmid:11485574 |
Murillo-RodrÃguez E et al. | Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. | 2001 | Neuroreport | pmid:11447321 |
Di Marzo V et al. | Anandamide: some like it hot. | 2001 | Trends Pharmacol. Sci. | pmid:11431028 |
Ueda N et al. | Alkaline and acid amidases hydrolyzing anandamide and other N-acylethanolamines. | 2001 | World Rev Nutr Diet | pmid:11935959 |
Hansen HS et al. | When and where are N-acylethanolamine phospholipids and anandamide formed? | 2001 | World Rev Nutr Diet | pmid:11935960 |