Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Grider JR et al. | Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19589944 |
Shimozawa N et al. | Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17023553 |
Burdyga G et al. | Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20430875 |
Garcia N et al. | Systemic and portal hemodynamic effects of anandamide. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11123193 |
DeMorrow S et al. | The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18832445 |
Mahavadi S et al. | Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24407588 |
Yang YY et al. | Roles of anandamide in the hepatic microcirculation in cirrhotic rats. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16407591 |
Moezi L et al. | Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18703639 |
Seagard JL et al. | Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:14615281 |
Bátkai S et al. | Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17557913 |
Mukhopadhyay S et al. | Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12003810 |
Bátkai S et al. | Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17434980 |
Pacher P et al. | Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15821037 |
Awumey EM et al. | Is there a role for anandamide in cardiovascular regulation? Insights from studies of endocannabinoid metabolism. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16014613 |
Wahn H et al. | The endocannabinoid arachidonyl ethanolamide (anandamide) increases pulmonary arterial pressure via cyclooxygenase-2 products in isolated rabbit lungs. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16055511 |
Thomas KC et al. | Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21949157 |
Morty RE and Kuebler WM | TRPV4: an exciting new target to promote alveolocapillary barrier function. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25281637 |
Dean C | Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21940402 |
Roy A et al. | Stress peptide PACAP engages multiple signaling pathways within the carotid body to initiate excitatory responses in respiratory and sympathetic chemosensory afferents. | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23594614 |
Dean C | Endocannabinoid modulation of sympathetic and cardiovascular responses to acute stress in the periaqueductal gray of the rat. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21228344 |
Williams JL et al. | K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18703414 |
Silva GB et al. | Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23220721 |
Xu H et al. | Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17913835 |
Johnson RP et al. | System-specific O2 sensitivity of the tandem pore domain K+ channel TASK-1. | 2004 | Am. J. Physiol., Cell Physiol. | pmid:14576090 |
Li Q et al. | Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22173869 |
Sade H et al. | Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids. | 2006 | Am. J. Physiol., Cell Physiol. | pmid:16107501 |
Tang B et al. | Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19188660 |
Kohro S et al. | Reductions in levels of bacterial superantigens/cannabinoids by plasma exchange in a patient with severe toxic shock syndrome. | 2004 | Anaesth Intensive Care | pmid:15675223 |
Marchioni C et al. | A column switching ultrahigh-performance liquid chromatography-tandem mass spectrometry method to determine anandamide and 2-arachidonoylglycerol in plasma samples. | 2017 | Anal Bioanal Chem | pmid:28337517 |
Lam PM et al. | Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20835819 |
Kasai HF et al. | Studies on high-energy collision-induced dissociation of endogenous cannabinoids: 2-arachidonoylglycerol and n-arachidonoylethanolamide in FAB-mass spectrometry. | 2006 | Anal Sci | pmid:16837740 |
Kasai HF et al. | Analyses of anandamide and endocannabinoid-like compounds using collision-induced dissociation in fast atom bombardment ionization-mass spectrometry and gas chromatography/chemical ionization-mass spectrometry. | 2003 | Anal Sci | pmid:14696920 |
Ozalp A and Barroso B | Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. | 2009 | Anal. Biochem. | pmid:19665986 |
Richardson D et al. | Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. | 2007 | Anal. Biochem. | pmid:17141174 |
Lam PM et al. | Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma. | 2008 | Anal. Biochem. | pmid:18555789 |
Fezza F et al. | Radiochromatographic assay of N-acyl-phosphatidylethanolamine-specific phospholipase D activity. | 2005 | Anal. Biochem. | pmid:15766717 |
Wilson SJ et al. | A high-throughput-compatible assay for determining the activity of fatty acid amide hydrolase. | 2003 | Anal. Biochem. | pmid:12814631 |
Qin C et al. | Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. | 1998 | Anal. Biochem. | pmid:9683506 |
Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Wang Y et al. | A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening. | 2006 | Anal. Biochem. | pmid:16707086 |
Marczylo TH et al. | Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:20026294 |
Schreiber D et al. | Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. | 2007 | Anal. Biochem. | pmid:17196922 |
Marczylo TH et al. | A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. | 2009 | Anal. Biochem. | pmid:18823934 |
Wang Y et al. | Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. | 2001 | Anal. Biochem. | pmid:11412008 |
Muccioli GG and Stella N | An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. | 2008 | Anal. Biochem. | pmid:17981259 |
Williams J et al. | Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. | 2007 | Anal. Chem. | pmid:17600384 |
Bagavandoss P and Grimshaw S | Temporal and spatial distribution of the cannabinoid receptors (CB1, CB2) and fatty acid amide hydroxylase in the rat ovary. | 2010 | Anat Rec (Hoboken) | pmid:20665820 |
Aquila S et al. | Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. | 2010 | Anat Rec (Hoboken) | pmid:19938110 |
Schelegle ES | Functional morphology and physiology of slowly adapting pulmonary stretch receptors. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494485 |
Lee LY et al. | Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494486 |