Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang H et al. | Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14645706 |
Grimaldi P et al. | The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19541620 |
Alger BE | Endocannabinoids: getting the message across. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15173576 |
Adermark L and Lovinger DM | Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18077376 |
Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
Schuel H et al. | Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8052642 |
Scorticati C et al. | The effect of anandamide on prolactin secretion is modulated by estrogen. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12578974 |
Das SK et al. | Cannabinoid ligand-receptor signaling in the mouse uterus. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7753807 |
Facci L et al. | Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7724569 |
Hill MN et al. | Endogenous cannabinoid signaling is essential for stress adaptation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20439721 |
Devane WA and Axelrod J | Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022836 |
Paria BC et al. | The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568154 |
Mechoulam R and Deutsch DG | Toward an anandamide transporter. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16314567 |
Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
Glaser ST et al. | Evidence against the presence of an anandamide transporter. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12655057 |
Collin C et al. | Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7479747 |
Dinh TP et al. | Brain monoglyceride lipase participating in endocannabinoid inactivation. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12136125 |
Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
Calignano A et al. | A role for the endogenous cannabinoid system in the peripheral control of pain initiation. | 2000 | Prog. Brain Res. | pmid:11098711 |
Iannotti FA et al. | Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. | 2016 | Prog. Lipid Res. | pmid:26965148 |