Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
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| Maccarrone M et al. | Anandamide uptake by human endothelial cells and its regulation by nitric oxide. | 2000 | J. Biol. Chem. | pmid:10788462 |
| Yagen B and Burstein S | Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10798298 |
| Costa B et al. | Precipitated and spontaneous withdrawal in rats tolerant to anandamide. | 2000 | Psychopharmacology (Berl.) | pmid:10805606 |
| Braud S et al. | Activation of rabbit blood platelets by anandamide through its cleavage into arachidonic acid. | 2000 | FEBS Lett. | pmid:10760504 |
| Hao S et al. | Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. | 2000 | Eur. J. Pharmacol. | pmid:10762668 |
| Stefano GB | Endocannabinoid immune and vascular signaling. | 2000 | Acta Pharmacol. Sin. | pmid:11603279 |
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| Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
| Hansen HH et al. | Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons. | 2000 | J. Neurochem. | pmid:10899965 |
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| Palmer SL et al. | Natural and synthetic endocannabinoids and their structure-activity relationships. | 2000 | Curr. Pharm. Des. | pmid:10903399 |
| Szöke E et al. | Interacting effects of capsaicin and anandamide on intracellular calcium in sensory neurones. | 2000 | Neuroreport | pmid:10884049 |
| Szolcsányi J | Anandamide and the question of its functional role for activation of capsaicin receptors. | 2000 | Trends Pharmacol. Sci. | pmid:10838604 |
| Palkovits M | [The brain and the pain: neurotransmitters and neuronal pathways of pain perception and response]. | 2000 | Orv Hetil | pmid:11184247 |
| Maccarrone M and Finazzi-Agró A | Platelet activation: a new vascular activity of anandamide. | 2000 | FEBS Lett. | pmid:11184253 |
| Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
| Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
| Grainger J and Boachie-Ansah G | Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | 2001 | Br. J. Pharmacol. | pmid:11682448 |
| Farquhar-Smith WP and Rice AS | Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. | 2001 | Anesthesiology | pmid:11374613 |
| Ralevic V et al. | Cannabinoid activation of recombinant and endogenous vanilloid receptors. | 2001 | Eur. J. Pharmacol. | pmid:11672565 |
| Christopoulos A and Wilson K | Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. | 2001 | Brain Res. | pmid:11578621 |
| White R et al. | Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | 2001 | Br. J. Pharmacol. | pmid:11606334 |
| Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
| Wagner JA et al. | Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. | 2001 | Eur. J. Pharmacol. | pmid:11448486 |
| Boger DL et al. | alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412972 |
| Mendizábal VE et al. | Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. | 2001 | Eur. J. Pharmacol. | pmid:11567656 |
| Izzo AA et al. | Effect of vanilloid drugs on gastrointestinal transit in mice. | 2001 | Br. J. Pharmacol. | pmid:11264233 |
| Baker D et al. | Endocannabinoids control spasticity in a multiple sclerosis model. | 2001 | FASEB J. | pmid:11156943 |
| Gauldie SD et al. | Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. | 2001 | Br. J. Pharmacol. | pmid:11159713 |
| Tognetto M et al. | Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. | 2001 | J. Neurosci. | pmid:11160380 |
| MacCarrone M et al. | Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. | 2001 | Eur. J. Biochem. | pmid:11168423 |
| Hansen HH et al. | Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death. | 2001 | J. Neurochem. | pmid:11145976 |
| Matias I et al. | Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. | 2001 | Brain Res. Mol. Brain Res. | pmid:11245916 |
| Jonsson KO et al. | Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. | 2001 | Br. J. Pharmacol. | pmid:11498512 |
| Craib SJ et al. | A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. | 2001 | Br. J. Pharmacol. | pmid:11522594 |
| Hayase T et al. | Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. | 2001 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:11828716 |
| Deutsch DG et al. | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. | 2001 | J. Biol. Chem. | pmid:11118429 |
| Garcia N et al. | Systemic and portal hemodynamic effects of anandamide. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11123193 |
| Kagota S et al. | 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. | 2001 | Eur. J. Pharmacol. | pmid:11275004 |
| Bisogno T et al. | The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. | 2001 | Eur. J. Biochem. | pmid:11277920 |
| De Petrocellis L et al. | The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. | 2001 | J. Biol. Chem. | pmid:11278420 |
| Jacobsson SO and Fowler CJ | Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. | 2001 | Br. J. Pharmacol. | pmid:11309246 |
| Quistad GB et al. | Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11350214 |
| Day TA et al. | Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. | 2001 | Mol. Pharmacol. | pmid:11353795 |
| Kobayashi Y et al. | Activation by 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, of p42/44 mitogen-activated protein kinase in HL-60 cells. | 2001 | J. Biochem. | pmid:11328586 |
| Möhle R et al. | Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. | 2001 | Ann. N. Y. Acad. Sci. | pmid:11458515 |
| Di Marzo V et al. | Anandamide: some like it hot. | 2001 | Trends Pharmacol. Sci. | pmid:11431028 |
| Ueda N et al. | Alkaline and acid amidases hydrolyzing anandamide and other N-acylethanolamines. | 2001 | World Rev Nutr Diet | pmid:11935959 |