Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sugiura T et al. | Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. | 2000 | J. Biol. Chem. | pmid:10617657 |
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Fernandez-Patron C et al. | Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction. | 2000 | Circ. Res. | pmid:11029402 |
Maccarrone M et al. | Anandamide and 2-arachidonoylglycerol inhibit fatty acid amide hydrolase by activating the lipoxygenase pathway of the arachidonate cascade. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11095952 |
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Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
Stefano GB | Endocannabinoid immune and vascular signaling. | 2000 | Acta Pharmacol. Sin. | pmid:11603279 |
Martin BR et al. | Cannabinoid properties of methylfluorophosphonate analogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945879 |
Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
Oz M et al. | Endogenous cannabinoid anandamide directly inhibits voltage-dependent Ca(2+) fluxes in rabbit T-tubule membranes. | 2000 | Eur. J. Pharmacol. | pmid:10980258 |
Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
Hansen HH et al. | Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons. | 2000 | J. Neurochem. | pmid:10899965 |
Fimiani C et al. | Antagonism of LPS and IFN-gamma induced iNOS expression in human atrial endothelia by morphine, anandamide, and estrogen. | 2000 | Acta Pharmacol. Sin. | pmid:11324436 |
Di Marzo T et al. | Endocannabinoids: new targets for drug development. | 2000 | Curr. Pharm. Des. | pmid:10903398 |
Palmer SL et al. | Natural and synthetic endocannabinoids and their structure-activity relationships. | 2000 | Curr. Pharm. Des. | pmid:10903399 |
Szöke E et al. | Interacting effects of capsaicin and anandamide on intracellular calcium in sensory neurones. | 2000 | Neuroreport | pmid:10884049 |
Szolcsányi J | Anandamide and the question of its functional role for activation of capsaicin receptors. | 2000 | Trends Pharmacol. Sci. | pmid:10838604 |
Piomelli D et al. | The endocannabinoid system as a target for therapeutic drugs. | 2000 | Trends Pharmacol. Sci. | pmid:10838609 |
Hohmann AG and Herkenham M | Localization of cannabinoid CB(1) receptor mRNA in neuronal subpopulations of rat striatum: a double-label in situ hybridization study. | 2000 | Synapse | pmid:10842353 |
Spicuzza L et al. | Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves. | 2000 | Br. J. Pharmacol. | pmid:10928980 |
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Hillard CJ | Endocannabinoids and vascular function. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871291 |
Song ZH and Zhong M | CB1 cannabinoid receptor-mediated cell migration. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871313 |
Tytgat J et al. | Cannabinoid mimics in chocolate utilized as an argument in court. | 2000 | Int. J. Legal Med. | pmid:10876983 |
Andersson M et al. | Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide. | 2000 | Arch. Toxicol. | pmid:10877002 |
Maccarrone M et al. | Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. | 2000 | Lancet | pmid:10776746 |
Palkovits M | [The brain and the pain: neurotransmitters and neuronal pathways of pain perception and response]. | 2000 | Orv Hetil | pmid:11184247 |
Di Marzo V et al. | Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease. | 2000 | FASEB J. | pmid:10877836 |
Maccarrone M and Finazzi-Agró A | Platelet activation: a new vascular activity of anandamide. | 2000 | FEBS Lett. | pmid:11184253 |