Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Smaga I et al. | Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures. | 2014 | Neurotox Res | pmid:24652522 |
pmid:24671517 | ||||
pmid:24674601 | ||||
Baranowska-Kuczko M et al. | Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24682422 |
pmid:24687644 | ||||
Jackson AR et al. | Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. | 2014 | PLoS ONE | pmid:24699635 |
Sun LJ et al. | Endocannabinoid system activation contributes to glucose metabolism disorders of hepatocytes and promotes hepatitis C virus replication. | 2014 | Int. J. Infect. Dis. | pmid:24704332 |
Kaczocha M et al. | Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. | 2014 | PLoS ONE | pmid:24705380 |
pmid:24705535 | ||||
Nader J et al. | Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. | 2014 | Neuropharmacology | pmid:24709540 |
pmid:24717329 | ||||
Ohno-Shosaku T and Kano M | Endocannabinoid-mediated retrograde modulation of synaptic transmission. | 2014 | Curr. Opin. Neurobiol. | pmid:24747340 |
pmid:24747871 | ||||
Al Kury LT et al. | Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes. | 2014 | Br. J. Pharmacol. | pmid:24758718 |
Hama AT et al. | Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain. | 2014 | PLoS ONE | pmid:24788435 |
pmid:24788457 | ||||
Park SW et al. | Anticancer effects of anandamide on head and neck squamous cell carcinoma cells via the production of receptor-independent reactive oxygen species. | 2015 | Head Neck | pmid:24797795 |
Ravi J et al. | FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway. | 2014 | Oncotarget | pmid:24811863 |
pmid:24813296 | ||||
Scotchie JG et al. | Endocannabinoid regulation in human endometrium across the menstrual cycle. | 2015 | Reprod Sci | pmid:24819878 |
Pietrzak RH et al. | Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. | 2014 | Neuropsychopharmacology | pmid:24820537 |
Jergas B et al. | O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24853577 |
Wiley JL et al. | Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. | 2014 | Eur. J. Pharmacol. | pmid:24858366 |
Navarria A et al. | The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. | 2014 | Pharmacol. Res. | pmid:24861565 |
Lu W et al. | Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. | 2014 | Mol Brain | pmid:24886791 |
Gómez R et al. | Endogenous cannabinoid anandamide impairs cell growth and induces apoptosis in chondrocytes. | 2014 | J. Orthop. Res. | pmid:24902823 |
pmid:24911079 | ||||
Pulgar VM et al. | Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis. | 2014 | Hypertension | pmid:24935942 |
Dong W et al. | Simulation of Swanson's literature-based discovery: anandamide treatment inhibits growth of gastric cancer cells in vitro and in silico. | 2014 | PLoS ONE | pmid:24949851 |
pmid:24979612 | ||||
pmid:24980781 | ||||
Bluett RJ et al. | Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. | 2014 | Transl Psychiatry | pmid:25004388 |
Cipriano M et al. | The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells. | 2014 | BMC Res Notes | pmid:25012825 |
Alpár A et al. | Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling. | 2014 | Nat Commun | pmid:25030704 |
Laprairie RB et al. | Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons. | 2014 | J. Biol. Chem. | pmid:25037227 |
Lau BK et al. | Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. | 2014 | Br. J. Pharmacol. | pmid:25041240 |
Fezza F et al. | Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. | 2014 | Mol. Cell. Neurosci. | pmid:25064144 |
Björklund E et al. | Involvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study. | 2014 | PLoS ONE | pmid:25078278 |
Yang K et al. | Differential regulation of NMDAR and NMDAR-mediated metaplasticity by anandamide and 2-AG in the hippocampus. | 2014 | Hippocampus | pmid:25087967 |
pmid:25088244 | ||||
pmid:25098345 | ||||
pmid:25129827 | ||||
Sexton M et al. | Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters. | 2014 | Inflammopharmacology | pmid:25135301 |
Jia J et al. | Anandamide protects HT22 cells exposed to hydrogen peroxide by inhibiting CB1 receptor-mediated type 2 NADPH oxidase. | 2014 | Oxid Med Cell Longev | pmid:25136404 |
pmid:25195527 | ||||
pmid:25204580 | ||||
pmid:25205244 | ||||
pmid:25212838 | ||||
Özdemir B et al. | Endocannabinoids and inflammatory response in periodontal ligament cells. | 2014 | PLoS ONE | pmid:25226300 |
pmid:25229205 |