Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Maccarrone M et al. | Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. | 2008 | Nat. Neurosci. | pmid:18204441 |
| Paradisi A et al. | Anandamide regulates keratinocyte differentiation by inducing DNA methylation in a CB1 receptor-dependent manner. | 2008 | J. Biol. Chem. | pmid:18165231 |
| Hill MN et al. | Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report. | 2008 | Pharmacopsychiatry | pmid:18311684 |
| Migliarini B and Carnevali O | Anandamide modulates growth and lipid metabolism in the zebrafish Danio rerio. | 2008 | Mol. Cell. Endocrinol. | pmid:18342434 |
| De Oliveira Alvares L et al. | Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms. | 2008 | Neurobiol Learn Mem | pmid:18342551 |
| Engel MA et al. | Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. | 2008 | J. Physiol. Pharmacol. | pmid:19212003 |
| Mallat A and Lotersztajn S | Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis. | 2008 | Diabetes Metab. | pmid:19195630 |
| Di Marzo V | Endocannabinoids: synthesis and degradation. | 2008 | Rev. Physiol. Biochem. Pharmacol. | pmid:18481028 |
| Pertwee RG | Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. | 2008 | Addict Biol | pmid:18482430 |
| Rueda-Orozco PE et al. | Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats. | 2008 | Neuropharmacology | pmid:18501388 |
| Neelands TR et al. | Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons. | 2008 | Inflamm. Res. | pmid:18777111 |
| Scherma M et al. | Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18725543 |
| Ho WS et al. | 'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. | 2008 | Br. J. Pharmacol. | pmid:18695637 |
| Taylor AH et al. | The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy. | 2007 Sep-Oct | Hum. Reprod. Update | pmid:17584820 |
| Sakamoto Y et al. | Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. | 2007 Sep-Oct | ASAIO J. | pmid:17885340 |
| De Petrocellis L et al. | Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. | 2007 | Exp. Cell Res. | pmid:17428469 |
| Richardson D et al. | Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. | 2007 | Anal. Biochem. | pmid:17141174 |
| Starowicz K et al. | Biochemistry and pharmacology of endovanilloids. | 2007 | Pharmacol. Ther. | pmid:17349697 |
| Bátkai S et al. | Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17557913 |
| Williams J et al. | Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. | 2007 | Anal. Chem. | pmid:17600384 |
| Esposito G et al. | Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545311 |
| Karanian DA et al. | Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545313 |
| Velenovská M and Fisar Z | Effect of cannabinoids on platelet serotonin uptake. | 2007 | Addict Biol | pmid:17508987 |
| Brizzi A et al. | Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. | 2007 | Bioorg. Med. Chem. | pmid:17561406 |
| Hill MN et al. | Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. | 2007 | J. Neurochem. | pmid:17561935 |
| Leweke FM et al. | Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. | 2007 | Schizophr. Res. | pmid:17566707 |
| Ali AB | Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus. | 2007 | J. Neurophysiol. | pmid:17567776 |
| Fischbach T et al. | Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats. | 2007 | J. Neurophysiol. | pmid:17581853 |
| Saitoh C et al. | The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder. | 2007 | Eur. J. Pharmacol. | pmid:17586490 |
| Cavuoto P et al. | Effects of cannabinoid receptors on skeletal muscle oxidative pathways. | 2007 | Mol. Cell. Endocrinol. | pmid:17270342 |
| Duarte CD et al. | Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. | 2007 | Bioorg. Med. Chem. | pmid:17275312 |
| Lam FF et al. | Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint. | 2007 | Life Sci. | pmid:17275857 |
| Coopman K et al. | Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis. | 2007 | Int. Immunopharmacol. | pmid:17276894 |
| Jia Y and Lee LY | Role of TRPV receptors in respiratory diseases. | 2007 | Biochim. Biophys. Acta | pmid:17346945 |
| Solinas M et al. | Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17351107 |
| Centonze D et al. | The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. | 2007 | Brain | pmid:17626034 |
| Spivak CE et al. | The endocannabinoid anandamide inhibits the function of alpha4beta2 nicotinic acetylcholine receptors. | 2007 | Mol. Pharmacol. | pmid:17628012 |
| Thors L et al. | Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. | 2007 | Br. J. Pharmacol. | pmid:17676056 |
| Oz M et al. | The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17682128 |
| Mulè F et al. | Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations. | 2007 | Pharmacol. Res. | pmid:17656103 |
| Iuvone T et al. | Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. | 2007 | J. Mol. Med. | pmid:17639288 |
| Eisenstein TK et al. | Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. | 2007 | J. Neuroimmunol. | pmid:17640739 |
| Pakdeechote P et al. | Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. | 2007 | Br. J. Pharmacol. | pmid:17641668 |
| Tanaka M et al. | The mRNA expression of fatty acid amide hydrolase in human whole blood correlates with sepsis. | 2007 | J. Endotoxin Res. | pmid:17621544 |
| Després JP | The endocannabinoid system: a new target for the regulation of energy balance and metabolism. | 2007 | Crit Pathw Cardiol | pmid:17667864 |
| Thors L et al. | The 'specific' tyrosine kinase inhibitor genistein inhibits the enzymic hydrolysis of anandamide: implications for anandamide uptake. | 2007 | Br. J. Pharmacol. | pmid:17325653 |
| Bátkai S et al. | Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. | 2007 | FASEB J. | pmid:17327359 |
| Cippitelli A et al. | The anandamide transport inhibitor AM404 reduces ethanol self-administration. | 2007 | Eur. J. Neurosci. | pmid:17650118 |
| Wang H et al. | Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17259073 |
| Adermark L and Lovinger DM | Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18077376 |
| Akerman S et al. | Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17018694 |
| Shimozawa N et al. | Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17023553 |
| Varvel SA et al. | Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. | 2007 | Neuropsychopharmacology | pmid:17047668 |
| Sarchielli P et al. | Endocannabinoids in chronic migraine: CSF findings suggest a system failure. | 2007 | Neuropsychopharmacology | pmid:17119542 |
| Chemin J et al. | Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels. | 2007 | J. Biol. Chem. | pmid:17121818 |
| Yang YY et al. | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. | 2007 | Liver Int. | pmid:17845532 |
| Ghasemi M et al. | Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. | 2007 | BJU Int. | pmid:17850365 |
| Cisneros JA et al. | Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. | 2007 | J. Med. Chem. | pmid:17764163 |
| Vandevoorde S et al. | Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. | 2007 | Br. J. Pharmacol. | pmid:17143303 |
| Evans RM et al. | Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. | 2007 | Br. J. Pharmacol. | pmid:17700720 |
| Wheal AJ et al. | Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. | 2007 | Br. J. Pharmacol. | pmid:17700721 |
| Matias I et al. | Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. | 2007 | Br. J. Pharmacol. | pmid:17704823 |
| Peroni RN et al. | Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats. | 2007 | Eur. J. Pharmacol. | pmid:17169358 |
| Herradón E et al. | Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta. | 2007 | Br. J. Pharmacol. | pmid:17704831 |
| Smid SD et al. | The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. | 2007 | Eur. J. Pharmacol. | pmid:17706636 |
| Hanus LO | Discovery and isolation of anandamide and other endocannabinoids. | 2007 | Chem. Biodivers. | pmid:17712821 |
| Okamoto Y et al. | Biosynthetic pathways of the endocannabinoid anandamide. | 2007 | Chem. Biodivers. | pmid:17712822 |
| Yuece B et al. | Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex. | 2007 | Neurogastroenterol. Motil. | pmid:17727394 |
| Bourne C et al. | Novel, potent THC/anandamide (hybrid) analogs. | 2007 | Bioorg. Med. Chem. | pmid:17827022 |
| Hiley CR and Hoi PM | Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? | 2007 | Cardiovasc Drug Rev | pmid:17445087 |
| Nucci C et al. | Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17591864 |
| Murakami T et al. | Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes. | 2007 | FEBS Lett. | pmid:17184778 |
| Gasperi V et al. | Endocannabinoids in adipocytes during differentiation and their role in glucose uptake. | 2007 | Cell. Mol. Life Sci. | pmid:17187172 |
| Côté M et al. | Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. | 2007 | Int J Obes (Lond) | pmid:17224929 |
| Smita K et al. | Anandamide: an update. | 2007 | Fundam Clin Pharmacol | pmid:17227440 |
| Braida D et al. | 5-HT1A receptors are involved in the anxiolytic effect of Delta9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. | 2007 | Eur. J. Pharmacol. | pmid:17116299 |
| Castelli MP et al. | Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2. | 2007 | Eur. J. Pharmacol. | pmid:17644084 |
| DeMorrow S et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. | 2007 | J. Biol. Chem. | pmid:17329257 |
| Ade KK and Lovinger DM | Anandamide regulates postnatal development of long-term synaptic plasticity in the rat dorsolateral striatum. | 2007 | J. Neurosci. | pmid:17329438 |
| Ortar G et al. | New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. | 2007 | J. Med. Chem. | pmid:18027904 |
| Blankman JL et al. | A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. | 2007 | Chem. Biol. | pmid:18096503 |
| Stengel PW et al. | Inhaled anandamide reduces leukotriene D4-induced airway obstruction in guinea pigs. | 2007 | Eur. J. Pharmacol. | pmid:17166495 |
| Xu H et al. | Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17913835 |
| Athanasiou A et al. | Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17931597 |
| Imming P | Fatty pain cures. | 2007 | Chem. Biol. | pmid:18096498 |
| Morgese MG et al. | Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. | 2007 | Exp. Neurol. | pmid:17900568 |
| King AR et al. | URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. | 2007 | Chem. Biol. | pmid:18096504 |
| Hillard CJ et al. | Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. | 2007 | J. Mol. Neurosci. | pmid:17901541 |
| Opitz CA et al. | Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. | 2007 | FEBS Lett. | pmid:17904123 |
| Joshi SR | Endocannabinoid system--a novel target for cardiometabolic risk. | 2007 | J Assoc Physicians India | pmid:17879500 |
| Mitchell VA et al. | Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models. | 2007 | Clin. Exp. Pharmacol. Physiol. | pmid:17880375 |
| Romano MR and Lograno MD | Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17652738 |
| Bentzen PJ and Lang F | Effect of anandamide on erythrocyte survival. | 2007 | Cell. Physiol. Biochem. | pmid:17975305 |
| Mukhopadhyay S and Tulis DA | Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. | 2007 | Cardiovasc Hematol Agents Med Chem | pmid:17979695 |
| Soria-Gómez E et al. | Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. | 2007 | Br. J. Pharmacol. | pmid:17549045 |
| Dainese E et al. | Modulation of the endocannabinoid system by lipid rafts. | 2007 | Curr. Med. Chem. | pmid:17979719 |
| Kim SR et al. | Roles of transient receptor potential vanilloid subtype 1 and cannabinoid type 1 receptors in the brain: neuroprotection versus neurotoxicity. | 2007 | Mol. Neurobiol. | pmid:17917113 |
| Hornig B | Endothelial vasodilatory cannabinoid receptor in the human pulmonary artery: a future option in the therapy of pulmonary hypertension? | 2007 | J. Hypertens. | pmid:17921811 |
| Kozłowska H et al. | Identification of the vasodilatory endothelial cannabinoid receptor in the human pulmonary artery. | 2007 | J. Hypertens. | pmid:17921818 |
| Kracke GR et al. | The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes. | 2007 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:17960365 |