Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Muccioli GG et al. | The endocannabinoid system links gut microbiota to adipogenesis. | 2010 | Mol. Syst. Biol. | pmid:20664638 |
Yang YY et al. | Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. | 2010 | J. Hepatol. | pmid:20626112 |
Soneji ND et al. | Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. | 2010 | Life Sci. | pmid:20598325 |
Gutierrez-Lopez MD et al. | Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. | 2010 | Br. J. Pharmacol. | pmid:20590579 |
Wheal AJ et al. | Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. | 2010 | Br. J. Pharmacol. | pmid:20590573 |
Rajesh M et al. | Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. | 2010 | Br. J. Pharmacol. | pmid:20590572 |
Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. | 2010 | Br. J. Pharmacol. | pmid:20590569 |
Thors L et al. | Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. | 2010 | Br. J. Pharmacol. | pmid:20590565 |
Lisboa SF et al. | Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning. | 2010 | Int. J. Neuropsychopharmacol. | pmid:20587131 |
Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
Suárez J et al. | Endocannabinoid system in the adult rat circumventricular areas: an immunohistochemical study. | 2010 | J. Comp. Neurol. | pmid:20533360 |
Weis F et al. | Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery. | 2010 | Br J Anaesth | pmid:20525978 |
Patsos HA et al. | The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. | 2010 | Int. J. Oncol. | pmid:20514410 |
Talevi R et al. | Is there a role for endocannabinoids in sperm-oviduct interaction? | 2010 | Reproduction | pmid:20511399 |
Sántha P et al. | The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons. | 2010 | Acta Physiol Hung | pmid:20511124 |
Ishiguro H et al. | Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. | 2011 | Synapse | pmid:20506567 |
Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
Dey R et al. | Endocannabinoids inhibit the growth of free-living amoebae. | 2010 | Antimicrob. Agents Chemother. | pmid:20479202 |
Naccarato M et al. | Possible Anandamide and Palmitoylethanolamide involvement in human stroke. | 2010 | Lipids Health Dis | pmid:20470384 |
Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
Pisani V et al. | Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients. | 2010 | Mov. Disord. | pmid:20461809 |
Oddi S et al. | Pitfalls and solutions in assaying anandamide transport in cells. | 2010 | J. Lipid Res. | pmid:20447929 |
Bari M et al. | Characterization of the endocannabinoid system in mouse embryonic stem cells. | 2011 | Stem Cells Dev. | pmid:20446814 |
Massa F et al. | Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. | 2010 | J. Neurosci. | pmid:20445053 |
Hill MN et al. | Endogenous cannabinoid signaling is essential for stress adaptation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20439721 |
Burdyga G et al. | Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20430875 |
Jumpertz R et al. | Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide. | 2010 | Exp. Clin. Endocrinol. Diabetes | pmid:20429051 |
Annuzzi G et al. | Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. | 2010 | Lipids Health Dis | pmid:20426869 |
Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
Placzek EA et al. | Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). | 2010 | J Pharm Biomed Anal | pmid:20417049 |
Spradley JM et al. | Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. | 2010 | Pharmacol. Res. | pmid:20416378 |
Ying-Ying Y and Lin HC | Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. | 2010 | Liver Int. | pmid:20408944 |
Nallendran V et al. | The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour. | 2010 | BJOG | pmid:20406230 |
Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
Hoot MR et al. | Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. | 2010 | Brain Res. | pmid:20380816 |
Wu WJ et al. | [Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells]. | 2010 | Zhonghua Gan Zang Bing Za Zhi | pmid:20380798 |
Taylor AH et al. | Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle. | 2010 | Histochem. Cell Biol. | pmid:20369362 |
Falenski KW et al. | FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. | 2010 | Neuropsychopharmacology | pmid:20357755 |
Davies JW et al. | Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population. | 2010 | Br J Anaesth | pmid:20354008 |
Greco R et al. | The endocannabinoid system and migraine. | 2010 | Exp. Neurol. | pmid:20353780 |
Hansen HS | Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain. | 2010 | Exp. Neurol. | pmid:20353771 |
Kim J and Alger BE | Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. | 2010 | Nat. Neurosci. | pmid:20348918 |
Frampton G et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. | 2010 | Exp. Cell Res. | pmid:20347808 |
Ali AB and Todorova M | Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. | 2010 | Eur. J. Neurosci. | pmid:20345910 |
Morera-Herreras T et al. | Regulation of subthalamic neuron activity by endocannabinoids. | 2010 | Synapse | pmid:20336631 |
Laezza C et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells. | 2010 | Endocr. Relat. Cancer | pmid:20304978 |
Muccioli GG | Endocannabinoid biosynthesis and inactivation, from simple to complex. | 2010 | Drug Discov. Today | pmid:20304091 |
Kozono S et al. | Involvement of the endocannabinoid system in periodontal healing. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20233580 |
Makwana R et al. | Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation. | 2010 | Br. J. Pharmacol. | pmid:20233228 |
Musella A et al. | Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. | 2010 | Neuroscience | pmid:20219639 |
Roser P et al. | Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists. | 2010 | World J. Biol. Psychiatry | pmid:20218784 |
Kobayashi N and Yamamoto Y | Hypoxic responses of arterial chemoreceptors in rabbits are primarily mediated by leak K channels. | 2010 | Adv. Exp. Med. Biol. | pmid:20217348 |
De Laurentiis A et al. | The hypothalamic endocannabinoid system participates in the secretion of oxytocin and tumor necrosis factor-alpha induced by lipopolysaccharide. | 2010 | J. Neuroimmunol. | pmid:20207018 |
Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
Rueda-Orozco PE et al. | Intrahippocampal administration of anandamide increases REM sleep. | 2010 | Neurosci. Lett. | pmid:20188142 |
Solinas M et al. | Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide. | 2010 | Psychopharmacology (Berl.) | pmid:20179908 |
Alptekin A et al. | The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels. | 2010 | Eur. J. Pharmacol. | pmid:20171208 |
Di Marzo V and De Petrocellis L | Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. | 2010 | Curr. Med. Chem. | pmid:20166923 |
Reggio PH | Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown. | 2010 | Curr. Med. Chem. | pmid:20166921 |
Tanimura A et al. | The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. | 2010 | Neuron | pmid:20159446 |
Ueda N et al. | N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). | 2010 | Prog. Lipid Res. | pmid:20152858 |
Lerner TN et al. | Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. | 2010 | J. Neurosci. | pmid:20147543 |
Bhaskaran MD and Smith BN | Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy. | 2010 | Exp. Neurol. | pmid:20144892 |
Onnis V et al. | Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. | 2010 | J. Med. Chem. | pmid:20143779 |
Moreno-Galindo EG et al. | Molecular basis for a high-potency open-channel block of Kv1.5 channel by the endocannabinoid anandamide. | 2010 | Mol. Pharmacol. | pmid:20133392 |
Snider NT et al. | Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications. | 2010 | Pharmacol. Rev. | pmid:20133390 |
Izzo AA and Sharkey KA | Cannabinoids and the gut: new developments and emerging concepts. | 2010 | Pharmacol. Ther. | pmid:20117132 |
Johannesson M et al. | Cloning, purification and characterization of non-human primate 12/15-lipoxygenases. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20106647 |
Zakrzeska A et al. | A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. | 2010 | Br. J. Pharmacol. | pmid:20105178 |
Cencioni MT et al. | Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. | 2010 | PLoS ONE | pmid:20098669 |
Ribeiro A et al. | Anandamide prior to sensitization increases cell-mediated immunity in mice. | 2010 | Int. Immunopharmacol. | pmid:20093200 |
Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
Aquila S et al. | Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. | 2010 | Br. J. Pharmacol. | pmid:20067470 |
Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
Yang Q et al. | Anandamide induces cell death through lipid rafts in hepatic stellate cells. | 2010 | J. Gastroenterol. Hepatol. | pmid:20059638 |
Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
Oz M et al. | The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism. | 2010 | J. Neurochem. | pmid:20050977 |
Li Q et al. | Electrophysiological effects of anandamide on rat myocardium. | 2009 | Br. J. Pharmacol. | pmid:20050190 |
Pamplona FA et al. | Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice. | 2010 | Neurosci. Lett. | pmid:20036315 |
Touriño C et al. | FAAH deficiency promotes energy storage and enhances the motivation for food. | 2010 | Int J Obes (Lond) | pmid:20029375 |
Marczylo TH et al. | Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:20026294 |
Guindon J and Beaulieu P | The role of the endogenous cannabinoid system in peripheral analgesia. | 2009 | Curr Mol Pharmacol | pmid:20021453 |
Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. | 2010 | Cardiovasc. Res. | pmid:19942623 |
Wiley JL and Burston JJ | Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:19941884 |
Aquila S et al. | Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. | 2010 | Anat Rec (Hoboken) | pmid:19938110 |
Catani MV et al. | Anandamide extends platelets survival through CB(1)-dependent Akt signaling. | 2010 | Cell. Mol. Life Sci. | pmid:19936621 |
Weis F et al. | Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. | 2010 | J. Mol. Cell. Cardiol. | pmid:19931541 |
Marco EM and Viveros MP | The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. | 2009 | Mini Rev Med Chem | pmid:19929814 |
Kaczocha M et al. | Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. | 2010 | J. Biol. Chem. | pmid:19926788 |
Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
Buznikov GA et al. | A putative 'pre-nervous' endocannabinoid system in early echinoderm development. | 2010 | Dev. Neurosci. | pmid:19907129 |
Ziegler CG et al. | Expression and function of endocannabinoid receptors in the human adrenal cortex. | 2010 | Horm. Metab. Res. | pmid:19862666 |
Fonseca BM et al. | Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. | 2009 | Reprod. Biol. Endocrinol. | pmid:19860893 |
Mendiguren A and Pineda J | Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. | 2009 | Br. J. Pharmacol. | pmid:19845674 |
Caraceni P et al. | Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. | 2010 | Liver Int. | pmid:19840245 |
Guindon J and Hohmann AG | The endocannabinoid system and pain. | 2009 | CNS Neurol Disord Drug Targets | pmid:19839937 |
Abalo R et al. | Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. | 2009 | Neurosci. Lett. | pmid:19819299 |
Romigi A et al. | Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy. | 2010 | Epilepsia | pmid:19817812 |