Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tsuboi K et al. | Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. | 2011 | Biochim. Biophys. Acta | pmid:21801852 |
| Lin QS et al. | Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. | 2011 | Brain Res. Bull. | pmid:21801815 |
| Theile JW and Cummins TR | Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide. | 2011 | Mol. Pharmacol. | pmid:21788423 |
| Goonawardena AV et al. | Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. | 2011 Oct-Nov | Neuropharmacology | pmid:21767554 |
| Hayase T | Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. | 2011 | BMC Pharmacol. | pmid:21767384 |
| Kopczyńska B et al. | Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. | 2011 | Eur. J. Pharmacol. | pmid:21756900 |
| Zoerner AA et al. | Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21752730 |
| Catanzaro G et al. | Effect of capacitation on the endocannabinoid system of mouse sperm. | 2011 | Mol. Cell. Endocrinol. | pmid:21723369 |
| Brailoiu GC et al. | Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. | 2011 | J. Biol. Chem. | pmid:21719698 |
| Zoerner AA et al. | Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma. | 2011 | Clin. Pharmacol. Ther. | pmid:21716266 |
| Busquets-Garcia A et al. | Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. | 2011 | Biol. Psychiatry | pmid:21684528 |
| MartÃn-Couce L et al. | Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. | 2011 | J. Med. Chem. | pmid:21675776 |
| Warzecha Z et al. | Role of sensory nerves in gastroprotective effect of anandamide in rats. | 2011 | J. Physiol. Pharmacol. | pmid:21673369 |
| Romani R et al. | Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? | 2011 | Biochimie | pmid:21664223 |
| Pamplona FA and Takahashi RN | Psychopharmacology of the endocannabinoids: far beyond anandamide. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21652605 |
| Whyte LS et al. | Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro. | 2012 | Br. J. Pharmacol. | pmid:21649637 |
| Hofmann ME et al. | Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. | 2011 | J. Physiol. (Lond.) | pmid:21646412 |
| Khanna IK and Alexander CW | Fatty acid amide hydrolase inhibitors--progress and potential. | 2011 | CNS Neurol Disord Drug Targets | pmid:21631410 |
| Shekhar C | Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. | 2011 | Chem. Biol. | pmid:21609833 |
| McHugh D et al. | Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. | 2012 | Br. J. Pharmacol. | pmid:21595653 |
| Liao YS et al. | [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts]. | 2011 | Zhonghua Zhong Liu Za Zhi | pmid:21575494 |
| Sordelli MS et al. | The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. | 2011 | PLoS ONE | pmid:21559512 |
| Scherma M et al. | The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. | 2012 | Br. J. Pharmacol. | pmid:21557729 |
| Arias-Carrión O et al. | Biochemical modulation of the sleep-wake cycle: endogenous sleep-inducing factors. | 2011 | J. Neurosci. Res. | pmid:21557294 |
| Umathe SN et al. | Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. | 2011 | Behav. Brain Res. | pmid:21549765 |
| Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
| Howlett AC et al. | Endocannabinoid tone versus constitutive activity of cannabinoid receptors. | 2011 | Br. J. Pharmacol. | pmid:21545414 |
| Qi J et al. | Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. | 2011 | J. Immunol. | pmid:21515789 |
| Engel MA et al. | Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. | 2011 | Neuropeptides | pmid:21514666 |
| Carr RL et al. | Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. | 2011 | Toxicol. Sci. | pmid:21507991 |
| Booker L et al. | The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. | 2012 | Br. J. Pharmacol. | pmid:21506952 |
| Gamaleddin I et al. | The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. | 2011 | Br. J. Pharmacol. | pmid:21501143 |
| Chiba T et al. | A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. | 2011 | J. Pharm. Pharmacol. | pmid:21492165 |
| Izzo AA and Deutsch DG | Unique pathway for anandamide synthesis and liver regeneration. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21490298 |
| Steiner AA et al. | The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. | 2011 | J. Physiol. (Lond.) | pmid:21486787 |
| Brighton PJ et al. | Characterization of the endocannabinoid system, CB(1) receptor signalling and desensitization in human myometrium. | 2011 | Br. J. Pharmacol. | pmid:21486283 |
| Rossi S et al. | Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis. | 2011 | Brain Behav. Immun. | pmid:21473912 |
| Huang L et al. | Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. | 2011 | Lab. Invest. | pmid:21464819 |
| Stewart JL and McMahon LR | The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys. | 2011 | Br. J. Pharmacol. | pmid:21449917 |
| Munguba H et al. | Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. | 2011 | Neurobiol Learn Mem | pmid:21440651 |
| Khasabova IA et al. | Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. | 2011 | Pharmacol. Res. | pmid:21440630 |
| Kuc C et al. | Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. | 2012 | Mol. Carcinog. | pmid:21432910 |
| Aberturas MR et al. | Anandamide-loaded nanoparticles: preparation and characterization. | 2011 | J Microencapsul | pmid:21425945 |
| Pinar-Sueiro S et al. | [Cannabinoid applications in glaucoma]. | 2011 | Arch Soc Esp Oftalmol | pmid:21414525 |
| Proto MC et al. | Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. | 2012 | J. Cell. Physiol. | pmid:21412772 |
| Mukhopadhyay B et al. | Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21383171 |
| Sarmad S et al. | Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. | 2011 | J. Neurochem. | pmid:21375532 |
| Latek D et al. | Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR. | 2011 | J Mol Model | pmid:21365223 |
| Gervasi MG et al. | Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. | 2011 | PLoS ONE | pmid:21347292 |
| Greco R et al. | Effects of anandamide in migraine: data from an animal model. | 2011 | J Headache Pain | pmid:21331757 |
| Signorello MG et al. | The anandamide effect on NO/cGMP pathway in human platelets. | 2011 | J. Cell. Biochem. | pmid:21328466 |
| Correa F et al. | The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. | 2011 | Brain Behav. Immun. | pmid:21310228 |
| Vinod KY et al. | Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. | 2012 | Addict Biol | pmid:21309960 |
| Quercioli A et al. | Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. | 2011 | Eur. Heart J. | pmid:21303779 |
| Walentiny DM et al. | The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. | 2011 | Eur. J. Pharmacol. | pmid:21300050 |
| Garami A et al. | Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. | 2011 | J. Neurosci. | pmid:21289181 |
| Sridar C et al. | Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. | 2011 | Drug Metab. Dispos. | pmid:21289075 |
| Reis GM et al. | Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. | 2011 | Life Sci. | pmid:21277864 |
| Wang W et al. | Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons. | 2011 | Neuropharmacology | pmid:21272594 |
| Hollis JH et al. | The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression. | 2011 | J. Neuroimmunol. | pmid:21262543 |
| Zschenderlein C et al. | Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. | 2011 | PLoS ONE | pmid:21249195 |
| Dean C | Endocannabinoid modulation of sympathetic and cardiovascular responses to acute stress in the periaqueductal gray of the rat. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21228344 |
| Jenkin KA et al. | Role for cannabinoid receptors in human proximal tubular hypertrophy. | 2010 | Cell. Physiol. Biochem. | pmid:21220919 |
| De Petrocellis L et al. | N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. | 2011 | Pharmacol. Res. | pmid:21215315 |
| Guindon J et al. | Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. | 2011 | Br. J. Pharmacol. | pmid:21198549 |
| Bari M et al. | The manifold actions of endocannabinoids on female and male reproductive events. | 2011 | Front Biosci (Landmark Ed) | pmid:21196184 |
| Di Marzo V | Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. | 2011 | Nat. Neurosci. | pmid:21187849 |
| Zaccagnino P et al. | Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria. | 2011 | FEBS Lett. | pmid:21187088 |
| Kotsikorou E et al. | Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55. | 2011 | Chem. Phys. Lipids | pmid:21185816 |
| Méndez-DÃaz M et al. | The endocannabinoid system modulates the valence of the emotion associated to food ingestion. | 2012 | Addict Biol | pmid:21182571 |
| Chadwick W et al. | Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. | 2010 | PLoS ONE | pmid:21179406 |
| Jumpertz R et al. | Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. | 2011 | J. Clin. Endocrinol. Metab. | pmid:21177788 |
| De Petrocellis L et al. | Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. | 2011 | Br. J. Pharmacol. | pmid:21175579 |
| Kawahara H et al. | Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. | 2011 | Br. J. Pharmacol. | pmid:21175570 |
| Gomes FV et al. | Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. | 2011 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:21111767 |
| Di Marzo V | Anandamide serves two masters in the brain. | 2010 | Nat. Neurosci. | pmid:21102567 |
| Long JZ et al. | An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. | 2011 | J. Lipid Res. | pmid:21097653 |
| Godlewski G et al. | Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. | 2010 | Chem. Biol. | pmid:21095576 |
| Chávez AE et al. | TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. | 2010 | Nat. Neurosci. | pmid:21076423 |
| Osman NA et al. | Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. | 2010 | Bioorg. Med. Chem. | pmid:21074998 |
| Edwards JG et al. | A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. | 2012 | Hippocampus | pmid:21069781 |
| Naidoo V et al. | A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. | 2011 | J. Mol. Neurosci. | pmid:21069475 |
| Amoako AA et al. | Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21056015 |
| Justinová Z et al. | Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. | 2011 | Addict Biol | pmid:21054689 |
| Xie S et al. | Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. | 2010 | Chem. Res. Toxicol. | pmid:21049984 |
| Cassano T et al. | Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. | 2011 | Psychopharmacology (Berl.) | pmid:21042794 |
| Morera-Herreras T et al. | Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. | 2011 | Psychopharmacology (Berl.) | pmid:20959968 |
| Hutchins HL et al. | Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells. | 2011 | J. Nutr. Biochem. | pmid:20951563 |
| Clapper JR et al. | Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | 2010 | Nat. Neurosci. | pmid:20852626 |
| Lam PM et al. | Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20835819 |
| Jiang S et al. | Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. | 2010 | J. Biol. Chem. | pmid:20826813 |
| Tree K et al. | Anandamide centrally depresses the respiratory rhythm generator of neonatal mice. | 2010 | Neuroscience | pmid:20800658 |
| Bobbala D et al. | Effect of anandamide in Plasmodium Berghei-infected mice. | 2010 | Cell. Physiol. Biochem. | pmid:20798520 |
| Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
| Mair KM et al. | Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. | 2010 | Br. J. Pharmacol. | pmid:20718749 |
| Pratt-Hyatt M et al. | Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide. | 2010 | Drug Metab. Dispos. | pmid:20702771 |
| Glaser ST and Kaczocha M | Cyclooxygenase-2 mediates anandamide metabolism in the mouse brain. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20702753 |
| Soltys J et al. | Regulation of neural progenitor cell fate by anandamide. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20691161 |
| Linsalata M et al. | Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. | 2010 | Anticancer Res. | pmid:20682986 |
| Bagavandoss P and Grimshaw S | Temporal and spatial distribution of the cannabinoid receptors (CB1, CB2) and fatty acid amide hydroxylase in the rat ovary. | 2010 | Anat Rec (Hoboken) | pmid:20665820 |