Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Smith M et al. | The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation. | 2015 | PLoS ONE | pmid:26414859 |
Gouveia-Figueira S et al. | Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. | 2015 | PLoS ONE | pmid:26406890 |
Kaczocha M et al. | Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. | 2014 | PLoS ONE | pmid:24705380 |
Jackson AR et al. | Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. | 2014 | PLoS ONE | pmid:24699635 |
Compagnucci C et al. | Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. | 2013 | PLoS ONE | pmid:23372698 |
Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
Zschenderlein C et al. | Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. | 2011 | PLoS ONE | pmid:21249195 |
Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
Hamtiaux L et al. | Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. | 2011 | PLoS ONE | pmid:22046372 |
Karlsson J et al. | Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. | 2017 | PLoS ONE | pmid:28910408 |
Murtaza G et al. | TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries. | 2017 | PLoS ONE | pmid:28301582 |
Palermo G et al. | Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets. | 2015 | PLoS Comput. Biol. | pmid:26111155 |
Brantl SA et al. | Mechanism of platelet activation induced by endocannabinoids in blood and plasma. | 2014 | Platelets | pmid:23789792 |
Gertsch J | Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. | 2008 | Planta Med. | pmid:18275004 |
Acone G et al. | Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. | 2009 | Placenta | pmid:19097644 |
Fonseca BM et al. | Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. | 2009 | Placenta | pmid:19560819 |
Vercelli CA et al. | Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. | 2009 | Placenta | pmid:19428101 |
Abán C et al. | Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis. | 2013 | Placenta | pmid:23122699 |
Brocato B et al. | Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. | 2013 | Placenta | pmid:24008071 |
Cella M et al. | Dual effect of anandamide on rat placenta nitric oxide synthesis. | 2008 | Placenta | pmid:18561998 |