Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ross RA et al. | Pharmacological characterization of the anandamide cyclooxygenase metabolite: prostaglandin E2 ethanolamide. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12023517 |
Maccarrone M et al. | Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. | 2002 | Biochem. J. | pmid:12010121 |
Romero J et al. | Fatty acid amide hydrolase localization in the human central nervous system: an immunohistochemical study. | 2002 | Brain Res. Mol. Brain Res. | pmid:12008024 |
Mukhopadhyay S et al. | Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12003810 |
Maccarrone M et al. | Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. | 2002 | Eur. J. Neurosci. | pmid:11982628 |
Gerdeman GL et al. | Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. | 2002 | Nat. Neurosci. | pmid:11976704 |
Ishii I and Chun J | Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors. | 2002 | Neuroreport | pmid:11973452 |
Gardiner SM et al. | Complex regional haemodynamic effects of anandamide in conscious rats. | 2002 | Br. J. Pharmacol. | pmid:11959791 |
Bisogno T et al. | Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. | 2002 | Curr. Pharm. Des. | pmid:11945157 |
Hansen HS et al. | When and where are N-acylethanolamine phospholipids and anandamide formed? | 2001 | World Rev Nutr Diet | pmid:11935960 |
Ueda N et al. | Alkaline and acid amidases hydrolyzing anandamide and other N-acylethanolamines. | 2001 | World Rev Nutr Diet | pmid:11935959 |
Valk P et al. | Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2. | 2000 | Hematol. J. | pmid:11920199 |
Walter L et al. | Astrocytes in culture produce anandamide and other acylethanolamides. | 2002 | J. Biol. Chem. | pmid:11916961 |
Lin YS and Lee LY | Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors. | 2002 | J. Physiol. (Lond.) | pmid:11897863 |
Harris D et al. | Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. | 2002 | J. Physiol. (Lond.) | pmid:11897858 |
Molina-Holgado F et al. | Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures. | 2002 | J. Neurosci. Res. | pmid:11891798 |
Wenger T et al. | The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats. | 2002 | Life Sci. | pmid:11883716 |
Ford WR et al. | Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts. | 2002 | Br. J. Pharmacol. | pmid:11877326 |
Luo C et al. | Anandamide inhibits excitatory transmission to rat substantia gelatinosa neurones in a manner different from that of capsaicin. | 2002 | Neurosci. Lett. | pmid:11872246 |
Di Marzo V et al. | A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. | 2002 | J. Pharmacol. Exp. Ther. | pmid:11861807 |
Hayase T et al. | Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. | 2001 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:11828716 |
Maccarrone M et al. | Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer. | 2002 | Mol. Hum. Reprod. | pmid:11818522 |
Laine K et al. | Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides. | 2002 | Invest. Ophthalmol. Vis. Sci. | pmid:11818382 |
Mechoulam R et al. | Cannabinoids and brain injury: therapeutic implications. | 2002 | Trends Mol Med | pmid:11815270 |
Martin BR et al. | Assessment of structural commonality between tetrahydrocannabinol and anandamide. | 2002 | Eur. J. Pharmacol. | pmid:11790376 |
Lever IJ and Malcangio M | CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. | 2002 | Br. J. Pharmacol. | pmid:11786475 |
Ros J et al. | Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. | 2002 | Gastroenterology | pmid:11781284 |
Izzo AA et al. | The gastrointestinal pharmacology of cannabinoids. | 2001 | Curr Opin Pharmacol | pmid:11757815 |
Begg M et al. | Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum. | 2002 | Eur. J. Pharmacol. | pmid:11755170 |
Darmani NA | The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. | 2002 | J. Pharmacol. Exp. Ther. | pmid:11752094 |
Al-Hayani A et al. | The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. | 2001 | Neuropharmacology | pmid:11747904 |
Chemin J et al. | Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. | 2001 | EMBO J. | pmid:11742980 |
López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. | 2001 | J. Med. Chem. | pmid:11741470 |
Molderings GJ et al. | Noradrenaline release-inhibiting receptors on PC12 cells devoid of alpha(2(-)) and CB(1) receptors: similarities to presynaptic imidazoline and edg receptors. | 2002 | Neurochem. Int. | pmid:11738482 |
Wagner JA et al. | Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. | 2001 | J. Am. Coll. Cardiol. | pmid:11738314 |
Hayase T et al. | Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. | 2001 | J. Pharm. Pharmacol. | pmid:11732755 |
Stamer WD et al. | Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. | 2001 | Eur. J. Pharmacol. | pmid:11730719 |
Karava V et al. | Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. | 2001 | FEBS Lett. | pmid:11728445 |
Gurwitz D and Weizman A | Fatty acid amide hydrolase inhibitors and the marijuana debate. | 2001 | Lancet | pmid:11705595 |
Jamshidi N and Taylor DA | Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. | 2001 | Br. J. Pharmacol. | pmid:11704633 |
RodrÃguez de Fonseca F et al. | An anorexic lipid mediator regulated by feeding. | 2001 | Nature | pmid:11700558 |
van der Stelt M et al. | Exogenous anandamide protects rat brain against acute neuronal injury in vivo. | 2001 | J. Neurosci. | pmid:11698588 |
Bifulco M et al. | Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. | 2001 | FASEB J. | pmid:11687506 |
Grainger J and Boachie-Ansah G | Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | 2001 | Br. J. Pharmacol. | pmid:11682448 |
Nogueron MI et al. | Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. | 2001 | J. Neurochem. | pmid:11677265 |
Kurihara J et al. | 2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves. | 2001 | Jpn. J. Pharmacol. | pmid:11676206 |
Ralevic V et al. | Cannabinoid activation of recombinant and endogenous vanilloid receptors. | 2001 | Eur. J. Pharmacol. | pmid:11672565 |
Berdyshev EV et al. | Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. | 2001 | FASEB J. | pmid:11641243 |
White R et al. | Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | 2001 | Br. J. Pharmacol. | pmid:11606334 |
Bisogno T et al. | Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. | 2001 | Br. J. Pharmacol. | pmid:11606325 |