Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Fibromyalgia D005356 4 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Brain Concussion D001924 5 associated lipids
Muscle Spasticity D009128 5 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Sleep Deprivation D012892 5 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Anorexia D000855 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Morphine Dependence D009021 9 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Migraine Disorders D008881 11 associated lipids
Learning Disorders D007859 11 associated lipids
Hepatitis D006505 11 associated lipids
Shock, Septic D012772 11 associated lipids
Overweight D050177 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypertension, Portal D006975 12 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Bradycardia D001919 13 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Neoplasms D009369 13 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Celiac Disease D002446 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Mycoses D009181 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Ueda N [Anandamide: an endogenous cannabinoid receptor agonist]. 1995 Seikagaku pmid:7594870
Varga K et al. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. 1995 Eur. J. Pharmacol. pmid:7589169
Guzmán M et al. Effects of anandamide on hepatic fatty acid metabolism. 1995 Biochem. Pharmacol. pmid:7575652
Sugiura T et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. 1995 Biochem. Biophys. Res. Commun. pmid:7575630
Paria BC et al. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7568154
Vela G et al. Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. 1995 Neuropharmacology pmid:7566503
Felder CC et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. 1995 Mol. Pharmacol. pmid:7565624
Ueda N et al. Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide. 1995 J. Biol. Chem. pmid:7559559
Hansen HS et al. Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. 1995 Biochim. Biophys. Acta pmid:7548201
Schmid PC et al. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. 1995 FEBS Lett. pmid:7498458
Hampson AJ et al. Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. 1995 Biochim. Biophys. Acta pmid:7488638
Collin C et al. Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7479747
Lee M et al. Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes. 1995 J. Pharmacol. Exp. Ther. pmid:7473135
Pei R et al. Low-fat yogurt consumption reduces biomarkers of chronic inflammation and inhibits markers of endotoxin exposure in healthy premenopausal women: a randomised controlled trial. 2017 Br. J. Nutr. pmid:29179781
Kondakala S et al. Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice. 2017 Toxicol. Appl. Pharmacol. pmid:29097212
pmid:29059679
Köse S et al. Human bone marrow mesenchymal stem cells secrete endocannabinoids that stimulate in vitro hematopoietic stem cell migration effectively comparable to beta-adrenergic stimulation. 2018 Exp. Hematol. pmid:29030083
pmid:29017758
Forner-Piquer I et al. Dose-Specific Effects of Di-Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish. 2017 Endocrinology pmid:28938452
Karlsson J et al. Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. 2017 PLoS ONE pmid:28910408
Martin GG et al. Endocannabinoid Interaction with Human FABP1: Impact of the T94A Variant. 2017 Biochemistry pmid:28853554
pmid:28768662
Maia J et al. The endocannabinoid system expression in the female reproductive tract is modulated by estrogen. 2017 J. Steroid Biochem. Mol. Biol. pmid:28743542
pmid:28583049
pmid:28577869
pmid:28529018
pmid:28515018
pmid:28478727
Almeida-Santos AF et al. 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. 2017 J. Psychopharmacol. (Oxford) pmid:28440729
pmid:28439004
pmid:28419871
Karwad MA et al. The role of CB in intestinal permeability and inflammation. 2017 FASEB J. pmid:28404744
Soni N et al. Anandamide and 2-AG are endogenously present within the laterodorsal tegmental nucleus: Functional implications for a role of eCBs in arousal. 2017 Brain Res. pmid:28404451
Di Scala C et al. Ceramide binding to anandamide increases its half-life and potentiates its cytotoxicity in human neuroblastoma cells. 2017 Chem. Phys. Lipids pmid:28389107
Marchioni C et al. A column switching ultrahigh-performance liquid chromatography-tandem mass spectrometry method to determine anandamide and 2-arachidonoylglycerol in plasma samples. 2017 Anal Bioanal Chem pmid:28337517
Bondarenko AI et al. Direct activation of Ca and voltage-gated potassium channels of large conductance by anandamide in endothelial cells does not support the presence of endothelial atypical cannabinoid receptor. 2017 Eur. J. Pharmacol. pmid:28327344
Murtaza G et al. TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries. 2017 PLoS ONE pmid:28301582
Cui N et al. Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin. 2017 Clin Ther pmid:28291580
pmid:28284861
Smaga I et al. Changes in the Brain Endocannabinoid System in Rat Models of Depression. 2017 Neurotox Res pmid:28247204
pmid:28220271
Quartu M et al. Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. 2017 Lipids Health Dis pmid:28103941
pmid:28065729
Argueta DA and DiPatrizio NV Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity. 2017 Physiol. Behav. pmid:28065722
Artegoitia VM et al. Endocannabinoids concentrations in plasma associated with feed efficiency and carcass composition of beef steers. 2016 J. Anim. Sci. pmid:28046144
Thompson Z et al. Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. 2017 Physiol. Behav. pmid:28017680
Kantae V et al. Quantitative profiling of endocannabinoids and related -acylethanolamines in human CSF using nano LC-MS/MS. 2017 J. Lipid Res. pmid:27999147
pmid:27997038
pmid:27966915
Schlabritz-Loutsevitch N et al. Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity. 2016 Med. Hypotheses pmid:27959272