Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hydock DS et al. | Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. | 2009 | J. Cardiovasc. Pharmacol. Ther. | pmid:19129423 |
Lin YS et al. | Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. | 2009 | J. Appl. Physiol. | pmid:19131477 |
Marco EM et al. | Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. | 2009 | Brain Res. | pmid:19133243 |
Ho WS and Gardiner SM | Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19133994 |
Doroshenko P and Renaud LP | Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. | 2009 | Neuroscience | pmid:19135504 |
Koethe D et al. | Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. | 2009 | J Neural Transm | pmid:19137236 |
Araújo JR et al. | Effect of cannabinoids upon the uptake of folic acid by BeWo cells. | 2009 | Pharmacology | pmid:19145103 |
Gratzke C et al. | Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147270 |
Prieto D | Editorial comment on: localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147273 |
Van Dross RT | Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. | 2009 | Mol. Carcinog. | pmid:19148897 |
EscartÃn-Pérez RE et al. | Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. | 2009 | Physiol. Behav. | pmid:19150453 |
Balas L et al. | Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. | 2009 | J. Med. Chem. | pmid:19161308 |
Snider NT et al. | A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. | 2009 | Mol. Pharmacol. | pmid:19171674 |
Vural IM et al. | Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. | 2009 | J Sex Med | pmid:19175867 |
Schlosburg JE et al. | Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. | 2009 | AAPS J | pmid:19184452 |
Tang B et al. | Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. | 2009 | Am. J. Respir. Cell Mol. Biol. | pmid:19188660 |
Cozzolino R et al. | A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. | 2010 | Invest New Drugs | pmid:19189054 |
Lissoni P et al. | The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. | 2008 Nov-Dec | Anticancer Res. | pmid:19189659 |
Ribeiro ML et al. | 17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. | 2009 | Reprod. Biomed. Online | pmid:19192341 |
Mallat A and Lotersztajn S | Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis. | 2008 | Diabetes Metab. | pmid:19195630 |
Navarrete CM et al. | Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. | 2009 | J. Neurochem. | pmid:19200337 |
El-Talatini MR et al. | The relationship between plasma levels of the endocannabinoid, anandamide, sex steroids, and gonadotrophins during the menstrual cycle. | 2010 | Fertil. Steril. | pmid:19200965 |
Engel MA et al. | Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. | 2008 | J. Physiol. Pharmacol. | pmid:19212003 |
Alenmyr L et al. | TRPV1-mediated itch in seasonal allergic rhinitis. | 2009 | Allergy | pmid:19220220 |
Gratzke C et al. | Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. | 2009 | J. Urol. | pmid:19237169 |
El-Talatini MR et al. | Localisation and function of the endocannabinoid system in the human ovary. | 2009 | PLoS ONE | pmid:19238202 |
Parker LA et al. | The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). | 2009 | Physiol. Behav. | pmid:19239915 |
Hiley CR | Endocannabinoids and the heart. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19276990 |
Potenzieri C et al. | Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. | 2009 | Brain Res. | pmid:19285051 |
De Petrocellis L and Di Marzo V | An introduction to the endocannabinoid system: from the early to the latest concepts. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285257 |
Borrelli F and Izzo AA | Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285259 |
Bermúdez-Silva FJ et al. | The role of the pancreatic endocannabinoid system in glucose metabolism. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285263 |
Cottone E et al. | Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. | 2009 | Neuroreport | pmid:19293731 |
Villanueva A et al. | Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. | 2009 | Shock | pmid:19295473 |
Kaczocha M et al. | Identification of intracellular carriers for the endocannabinoid anandamide. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19307565 |
Di Pasquale E et al. | The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. | 2009 | PLoS ONE | pmid:19330032 |
Brizzi A et al. | New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. | 2009 | J. Med. Chem. | pmid:19331413 |
Koethe D et al. | Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. | 2009 | Br J Psychiatry | pmid:19336792 |
Mangieri RA et al. | An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | 2009 | Psychopharmacology (Berl.) | pmid:19343330 |
Appendino G et al. | Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. | 2009 | J. Med. Chem. | pmid:19361197 |
El-Talatini MR et al. | Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. | 2009 | Hum. Reprod. | pmid:19363040 |
Carney ST et al. | Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. | 2009 | J Neuroimmune Pharmacol | pmid:19365734 |
Izzo AA et al. | Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. | 2009 | Br. J. Pharmacol. | pmid:19371345 |
Shaladi AM et al. | [Cannabinoids in the control of pain]. | 2008 | Recenti Prog Med | pmid:19388223 |
Ahn K et al. | Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. | 2009 | Chem. Biol. | pmid:19389627 |
Yates ML and Barker EL | Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. | 2009 | Mol. Pharmacol. | pmid:19389920 |
Miyato H et al. | Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. | 2009 | J. Surg. Res. | pmid:19394652 |
Hill MN et al. | Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. | 2009 | Psychoneuroendocrinology | pmid:19394765 |
Centonze D et al. | Altered anandamide degradation in attention-deficit/hyperactivity disorder. | 2009 | Neurology | pmid:19398708 |
Liu H et al. | Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. | 2009 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:19399401 |
Mazzola C et al. | Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. | 2009 | Learn. Mem. | pmid:19403796 |
Chen L et al. | Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. | 2009 | J Pain | pmid:19409856 |
Yang YY et al. | Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. | 2009 | Liver Int. | pmid:19413671 |
Hansen HS and Diep TA | N-acylethanolamines, anandamide and food intake. | 2009 | Biochem. Pharmacol. | pmid:19413995 |
Zoerner AA et al. | Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19414283 |
Vercelli CA et al. | Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. | 2009 | Placenta | pmid:19428101 |
Shen Y et al. | A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. | 2009 | J. Neurosci. | pmid:19439586 |
Fernandez-Solari J et al. | Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448903 |
Ribeiro A et al. | Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448906 |
Bradshaw HB et al. | The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. | 2009 | BMC Biochem. | pmid:19460156 |
Li D et al. | Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. | 2009 | J. Hypertens. | pmid:19462497 |
Mahmud A et al. | Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. | 2009 | Neuroscience | pmid:19463903 |
Vann RE et al. | Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. | 2009 | Eur. J. Pharmacol. | pmid:19470387 |
Brighton PJ et al. | Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. | 2009 | Mol. Endocrinol. | pmid:19477951 |
Zolese G et al. | Effect of acylethanolamides on lipid peroxidation and paraoxonase activity. | 2008 | Biofactors | pmid:19478424 |
Oddi S et al. | Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. | 2009 | Chem. Biol. | pmid:19481477 |
Vercelli CA et al. | Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. | 2009 | Reprod. Biomed. Online | pmid:19490788 |
Aquila S et al. | A new role of anandamide in human sperm: focus on metabolism. | 2009 | J. Cell. Physiol. | pmid:19492411 |
Straiker A and Mackie K | Cannabinoid signaling in inhibitory autaptic hippocampal neurons. | 2009 | Neuroscience | pmid:19501632 |
Kinsey SG et al. | Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19502530 |
Kingsley PJ and Marnett LJ | Analysis of endocannabinoids, their congeners and COX-2 metabolites. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19505857 |
Greco R et al. | Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. | 2010 | Cephalalgia | pmid:19515121 |
Dowie MJ et al. | Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. | 2009 | Neuroscience | pmid:19524019 |
Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
Maeda N et al. | Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. | 2009 | Fundam Clin Pharmacol | pmid:19527302 |
Palandra J et al. | Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19535304 |
Grimaldi P et al. | The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19541620 |
Karaliota S et al. | Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. | 2009 | Obesity (Silver Spring) | pmid:19543211 |
Batetta B et al. | Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. | 2009 | J. Nutr. | pmid:19549757 |
Murakami T et al. | Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. | 2009 | Int. Immunol. | pmid:19556302 |
Fonseca BM et al. | Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. | 2009 | Placenta | pmid:19560819 |
Correa F et al. | Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. | 2010 | Glia | pmid:19565660 |
Guasti L et al. | Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. | 2009 | Mol Pain | pmid:19570201 |
Bittner S et al. | TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. | 2009 | Brain | pmid:19570851 |
Reis GM et al. | Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. | 2009 | Life Sci. | pmid:19576231 |
Umathe SN et al. | Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19580839 |
Prestifilippo JP et al. | Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. | 2009 Sep-Oct | Alcohol Alcohol. | pmid:19589828 |
Grider JR et al. | Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19589944 |
Astarita G et al. | Targeted lipidomics as a tool to investigate endocannabinoid function. | 2009 | Int. Rev. Neurobiol. | pmid:19607960 |
Francavilla F et al. | Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. | 2009 | Endocrinology | pmid:19608651 |
Amorós I et al. | Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. | 2010 | J. Mol. Cell. Cardiol. | pmid:19616555 |
Panagis G et al. | Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. | 2008 | Curr Drug Abuse Rev | pmid:19630731 |
Okamoto Y et al. | Enzymatic formation of anandamide. | 2009 | Vitam. Horm. | pmid:19647106 |
Yates ML and Barker EL | Organized trafficking of anandamide and related lipids. | 2009 | Vitam. Horm. | pmid:19647107 |
Goodfellow CE and Glass M | Anandamide receptor signal transduction. | 2009 | Vitam. Horm. | pmid:19647109 |
Brown AJ and Robin Hiley C | Is GPR55 an anandamide receptor? | 2009 | Vitam. Horm. | pmid:19647110 |
Correa FG et al. | The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. | 2009 | Vitam. Horm. | pmid:19647114 |
Tóth A et al. | Anandamide and the vanilloid receptor (TRPV1). | 2009 | Vitam. Horm. | pmid:19647120 |
Pasquariello N et al. | Regulation of gene transcription and keratinocyte differentiation by anandamide. | 2009 | Vitam. Horm. | pmid:19647122 |
Alpini G and Demorrow S | Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. | 2009 | Vitam. Horm. | pmid:19647123 |