Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Karbarz MJ et al. | Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. | 2009 | Anesth. Analg. | pmid:19095868 |
Petrovszki Z et al. | The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. | 2012 | Anesth. Analg. | pmid:22451592 |
Romero TR et al. | CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. | 2013 | Anesth. Analg. | pmid:23302980 |
Okura D et al. | The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. | 2014 | Anesth. Analg. | pmid:24557103 |
Farquhar-Smith WP and Rice AS | A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia. | 2003 | Anesthesiology | pmid:14639155 |
Farquhar-Smith WP and Rice AS | Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. | 2001 | Anesthesiology | pmid:11374613 |
Schelling G et al. | Effects of general anesthesia on anandamide blood levels in humans. | 2006 | Anesthesiology | pmid:16436846 |
Möhle R et al. | Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. | 2001 | Ann. N. Y. Acad. Sci. | pmid:11458515 |
Pisani A et al. | High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients. | 2005 | Ann. Neurol. | pmid:15852389 |
Chiurchiù V et al. | Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. | 2013 | Ann. Neurol. | pmid:23447381 |
Katona I and Freund TF | Multiple functions of endocannabinoid signaling in the brain. | 2012 | Annu. Rev. Neurosci. | pmid:22524785 |
Linsalata M et al. | Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. | 2010 | Anticancer Res. | pmid:20682986 |
Lissoni P et al. | The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. | 2008 Nov-Dec | Anticancer Res. | pmid:19189659 |
Dey R et al. | Endocannabinoids inhibit the growth of free-living amoebae. | 2010 | Antimicrob. Agents Chemother. | pmid:20479202 |
Simpson CD et al. | A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance. | 2012 | Apoptosis | pmid:22488300 |
Fonseca BM et al. | The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. | 2013 | Apoptosis | pmid:24048885 |
Pinar-Sueiro S et al. | [Cannabinoid applications in glaucoma]. | 2011 | Arch Soc Esp Oftalmol | pmid:21414525 |
Fowler CJ et al. | Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. | 1999 | Arch. Biochem. Biophys. | pmid:9989926 |
Oz M et al. | Effects of saturated long-chain N-acylethanolamines on voltage-dependent Ca2+ fluxes in rabbit T-tubule membranes. | 2005 | Arch. Biochem. Biophys. | pmid:15639235 |
Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |