Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Van den Bossche I and Vanheel B | Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. | 2000 | Br. J. Pharmacol. | pmid:10960073 |
Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
Costa B and Colleoni M | Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. | 2000 | Eur. J. Pharmacol. | pmid:10781666 |
Sarker KP et al. | Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. | 2000 | FEBS Lett. | pmid:10781801 |
Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
Valk P et al. | Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2. | 2000 | Hematol. J. | pmid:11920199 |
Kunos G et al. | Endocannabinoids as cardiovascular modulators. | 2000 | Chem. Phys. Lipids | pmid:11106789 |
Bisogno T et al. | N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. | 2000 | Biochem. J. | pmid:11042139 |
Wiley JL et al. | Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. | 2000 | Life Sci. | pmid:10983852 |
Stefano GB et al. | 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. | 2000 | Pharmacol. Res. | pmid:10987990 |
Okamoto H et al. | Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. | 2000 | Thromb. Res. | pmid:10942792 |
Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
Maccarrone M et al. | Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. | 2000 | J. Biol. Chem. | pmid:10913156 |
Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
Muthian S et al. | Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734181 |
Wang Y et al. | Polymyxin B binds to anandamide and inhibits its cytotoxic effect. | 2000 | FEBS Lett. | pmid:10734225 |
Markey SP et al. | Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. | 2000 | J. Lipid Res. | pmid:10744787 |
Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
Ralevic V et al. | Cannabinoid activation of recombinant and endogenous vanilloid receptors. | 2001 | Eur. J. Pharmacol. | pmid:11672565 |
Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
Maingret F et al. | The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. | 2001 | EMBO J. | pmid:11226154 |
Gurwitz D and Weizman A | Fatty acid amide hydrolase inhibitors and the marijuana debate. | 2001 | Lancet | pmid:11705595 |
Rice AS | Cannabinoids and pain. | 2001 | Curr Opin Investig Drugs | pmid:11575713 |
Karava V et al. | Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. | 2001 | FEBS Lett. | pmid:11728445 |
Stamer WD et al. | Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. | 2001 | Eur. J. Pharmacol. | pmid:11730719 |
Hayase T et al. | Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. | 2001 | J. Pharm. Pharmacol. | pmid:11732755 |
Hansen HH et al. | Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. | 2001 | J. Neurochem. | pmid:11579150 |
Smith PJ and McQueen DS | Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. | 2001 | Br. J. Pharmacol. | pmid:11588121 |
Maccarrone M et al. | Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. | 2001 | Arch. Biochem. Biophys. | pmid:11556820 |
Crozier Willi G et al. | Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. | 2001 | Nestle Nutr Workshop Ser Clin Perform Programme | pmid:11510437 |
Stella N and Piomelli D | Receptor-dependent formation of endogenous cannabinoids in cortical neurons. | 2001 | Eur. J. Pharmacol. | pmid:11513837 |
Vellani V et al. | Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. | 2001 | J. Physiol. (Lond.) | pmid:11483711 |
Maccarrone M et al. | Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. | 2001 | J. Neurochem. | pmid:11461969 |
Ueda N et al. | Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. | 2001 | J. Biol. Chem. | pmid:11463796 |
Wagner JA et al. | Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. | 2001 | J. Am. Coll. Cardiol. | pmid:11738314 |
López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. | 2001 | J. Med. Chem. | pmid:11741470 |
Chemin J et al. | Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. | 2001 | EMBO J. | pmid:11742980 |
Bifulco M et al. | Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. | 2001 | FASEB J. | pmid:11687506 |
De Petrocellis L et al. | Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. | 2001 | FEBS Lett. | pmid:11602256 |
Bisogno T et al. | Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. | 2001 | Br. J. Pharmacol. | pmid:11606325 |
D'Souza DC and Kosten TR | Cannabinoid antagonists: a treatment in search of an illness. | 2001 | Arch. Gen. Psychiatry | pmid:11296092 |
Breivogel CS et al. | Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. | 2001 | Mol. Pharmacol. | pmid:11408610 |
Wang Y et al. | Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. | 2001 | Anal. Biochem. | pmid:11412008 |
De Petrocellis L et al. | The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. | 2001 | J. Neurochem. | pmid:11413249 |
Morisset V and Urban L | Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. | 2001 | J. Neurophysiol. | pmid:11431486 |
Bátkai S et al. | Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. | 2001 | Nat. Med. | pmid:11433348 |
Maccarrone M et al. | Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. | 2001 | J. Immunol. | pmid:11390466 |
Wenger T et al. | The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11394887 |
Maccarrone M et al. | Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. | 2001 | J. Neurochem. | pmid:11208922 |