Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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McGregor IS et al. | A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. | 1998 | Brain Res. | pmid:9748483 |
Schneider U et al. | Cannabinoid/anandamide system and schizophrenia: is there evidence for association? | 1998 | Pharmacopsychiatry | pmid:9754842 |
Stengel PW et al. | Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. | 1998 | Eur. J. Pharmacol. | pmid:9754939 |
Pestonjamasp VK and Burstein SH | Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. | 1998 | Biochim. Biophys. Acta | pmid:9795237 |
Bisogno T et al. | Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. | 1998 | Eur. J. Biochem. | pmid:9688276 |
Murillo-RodrÃguez E et al. | Anandamide modulates sleep and memory in rats. | 1998 | Brain Res. | pmid:9813364 |
Jaggar SI et al. | The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. | 1998 | Neurosci. Lett. | pmid:9774165 |
Fulton D and Quilley J | Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732371 |
Welch SP et al. | Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732392 |
Fields HL and Meng ID | Watching the pot boil. | 1998 | Nat. Med. | pmid:9734389 |
Pate DW et al. | Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. | 1998 | Life Sci. | pmid:9851310 |
Molina-Holgado F et al. | The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. | 1998 | FEBS Lett. | pmid:9738948 |
Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
Prevot V et al. | Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. | 1998 | Brain Res. | pmid:9593913 |
Di Marzo V | 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. | 1998 | Biochim. Biophys. Acta | pmid:9630590 |
Stefano GB et al. | Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. | 1998 | Brain Res. | pmid:9630717 |
Schmid PC et al. | Alternative pathways of anandamide biosynthesis in rat testes. | 1998 | Chem. Phys. Lipids | pmid:9631536 |
Varga K et al. | Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. | 1998 | FASEB J. | pmid:9707176 |
Mallet PE and Beninger RJ | Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. | 1998 | Life Sci. | pmid:9651110 |
De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |
Berdyshev E et al. | Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. | 1998 | Life Sci. | pmid:9718090 |
Jaggar SI et al. | The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. | 1998 | Pain | pmid:9696473 |
Bisogno T et al. | Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9703957 |
Kondo S et al. | Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. | 1998 | Arch. Biochem. Biophys. | pmid:9637740 |
Stefano GB et al. | Antagonism of LPS and IFN-gamma induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9641464 |
Stefano GB et al. | Long-term exposure of human blood vessels to HIV gp120, morphine, and anandamide increases endothelial adhesion of monocytes: uncoupling of nitric oxide release. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9641470 |
Mallet PE and Beninger RJ | The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. | 1998 | Psychopharmacology (Berl.) | pmid:9862397 |
Stahl SM | Getting stoned without inhaling: anandamide is the brain's natural marijuana. | 1998 | J Clin Psychiatry | pmid:9862600 |
Bonhaus DW et al. | Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9864268 |
Ueda N et al. | A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors. | 1998 | J. Med. Invest. | pmid:9864962 |
Mechoulam R et al. | Endocannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9831287 |
Navarro M and RodrÃguez de Fonseca F | The neurobiology of cannabinoid transmission: from anandamide signaling to higher cerebral functions and disease. | 1998 | Neurobiol. Dis. | pmid:9974172 |
Di Marzo V and Deutsch DG | Biochemistry of the endogenous ligands of cannabinoid receptors. | 1998 | Neurobiol. Dis. | pmid:9974173 |
Derocq JM et al. | The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. | 1998 | FEBS Lett. | pmid:9563506 |
Wiley JL et al. | Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. | 1998 | Eur. J. Pharmacol. | pmid:9760024 |
Axelrod J and Felder CC | Cannabinoid receptors and their endogenous agonist, anandamide. | 1998 | Neurochem. Res. | pmid:9566594 |
Lichtman AH et al. | Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. | 1998 | Eur. J. Pharmacol. | pmid:9797029 |
Randall MD and Kendall DA | Endocannabinoids: a new class of vasoactive substances. | 1998 | Trends Pharmacol. Sci. | pmid:9550942 |
Di Marzo V et al. | Interactions between synthetic vanilloids and the endogenous cannabinoid system. | 1998 | FEBS Lett. | pmid:9801167 |
Van der Kloot W et al. | Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. | 1998 | J. Physiol. (Lond.) | pmid:9508830 |
Stein EA et al. | Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. | 1998 | Neuropsychopharmacology | pmid:9803424 |
Di Marzo V et al. | The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. | 1998 | Biochem. J. | pmid:9512456 |
Randall MD and Kendall DA | Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. | 1998 | Eur. J. Pharmacol. | pmid:9617751 |
Adams IB et al. | Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9495885 |
Edgemond WS et al. | Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. | 1998 | Mol. Pharmacol. | pmid:9658204 |
Giuffrida A and Piomelli D | Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. | 1998 | FEBS Lett. | pmid:9498819 |
Tong W et al. | Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. | 1998 | J. Med. Chem. | pmid:9784095 |
Richardson JD et al. | Antihyperalgesic effects of spinal cannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9600630 |
Goparaju SK et al. | Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. | 1998 | FEBS Lett. | pmid:9475172 |
Hampson AJ et al. | Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. | 1998 | J. Neurochem. | pmid:9453561 |