Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Raichlen DA et al. | Exercise-induced endocannabinoid signaling is modulated by intensity. | 2013 | Eur. J. Appl. Physiol. | pmid:22990628 |
| Wellner N et al. | N-acylation of phosphatidylethanolamine and its biological functions in mammals. | 2013 | Biochim. Biophys. Acta | pmid:23000428 |
| Canseco-Alba A and RodrÃguez-Manzo G | Anandamide transforms noncopulating rats into sexually active animals. | 2013 | J Sex Med | pmid:22906359 |
| Gervasi MG et al. | Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle. | 2013 | PLoS ONE | pmid:23977311 |
| Zhang J et al. | Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. | 2013 | Sheng Li Xue Bao | pmid:23598867 |
| Ruginsk SG et al. | Anandamide modulates the neuroendocrine responses induced by extracellular volume expansion. | 2013 | Clin. Exp. Pharmacol. Physiol. | pmid:23875874 |
| Silvestri C et al. | Anandamide-derived prostamide F2α negatively regulates adipogenesis. | 2013 | J. Biol. Chem. | pmid:23801328 |
| Pryce G et al. | Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. | 2013 | Mult. Scler. | pmid:23625705 |
| Oh HA et al. | Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos. | 2013 | Mol. Hum. Reprod. | pmid:23112252 |
| Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |
| Abán C et al. | Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis. | 2013 | Placenta | pmid:23122699 |
| Romero TR et al. | Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors. | 2013 | Life Sci. | pmid:23123446 |
| Andrag E and Curtis MJ | Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids. | 2013 | Br. J. Pharmacol. | pmid:23713981 |
| Fogaça MV et al. | Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. | 2013 | Psychopharmacology (Berl.) | pmid:23183551 |
| De-May CL and Ali AB | Cell type-specific regulation of inhibition via cannabinoid type 1 receptors in rat neocortex. | 2013 | J. Neurophysiol. | pmid:23054605 |
| Coppola M and Mondola R | Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. | 2013 | Med. Hypotheses | pmid:23896215 |
| Khasabova IA et al. | Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. | 2013 | Neurobiol. Dis. | pmid:23644187 |
| Gesell FK et al. | Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. | 2013 | BMC Vet. Res. | pmid:24370333 |
| Nicotra LL et al. | Prostaglandin ethanolamides attenuate damage in a human explant colitis model. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23380599 |
| Fonseca BM et al. | Endogenous cannabinoids revisited: a biochemistry perspective. | 2013 Apr-May | Prostaglandins Other Lipid Mediat. | pmid:23474290 |
| Sexton M et al. | Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters. | 2014 | Inflammopharmacology | pmid:25135301 |
| Björklund E et al. | Involvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study. | 2014 | PLoS ONE | pmid:25078278 |
| Lau BK et al. | Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. | 2014 | Br. J. Pharmacol. | pmid:25041240 |
| Laprairie RB et al. | Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons. | 2014 | J. Biol. Chem. | pmid:25037227 |
| Cipriano M et al. | The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells. | 2014 | BMC Res Notes | pmid:25012825 |
| Bluett RJ et al. | Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. | 2014 | Transl Psychiatry | pmid:25004388 |
| Dong W et al. | Simulation of Swanson's literature-based discovery: anandamide treatment inhibits growth of gastric cancer cells in vitro and in silico. | 2014 | PLoS ONE | pmid:24949851 |
| Wiley JL et al. | Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. | 2014 | Eur. J. Pharmacol. | pmid:24858366 |
| Pietrzak RH et al. | Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. | 2014 | Neuropsychopharmacology | pmid:24820537 |
| Ravi J et al. | FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway. | 2014 | Oncotarget | pmid:24811863 |
| Hama AT et al. | Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain. | 2014 | PLoS ONE | pmid:24788435 |
| Navarria A et al. | The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. | 2014 | Pharmacol. Res. | pmid:24861565 |
| Al Kury LT et al. | Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes. | 2014 | Br. J. Pharmacol. | pmid:24758718 |
| Nader J et al. | Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. | 2014 | Neuropharmacology | pmid:24709540 |
| Kaczocha M et al. | Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. | 2014 | PLoS ONE | pmid:24705380 |
| Abdulnour J et al. | Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study. | 2014 | Obesity (Silver Spring) | pmid:23616305 |
| Hoyer FF et al. | Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice. | 2014 | J. Mol. Cell. Cardiol. | pmid:24286707 |
| Jergas B et al. | O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24853577 |
| Ohno-Shosaku T and Kano M | Endocannabinoid-mediated retrograde modulation of synaptic transmission. | 2014 | Curr. Opin. Neurobiol. | pmid:24747340 |
| Fowler CJ | Has FLAT fallen flat? | 2014 | Trends Pharmacol. Sci. | pmid:24398120 |
| Sousa-Valente J et al. | Anandamide in primary sensory neurons: too much of a good thing? | 2014 | Eur. J. Neurosci. | pmid:24494681 |
| Chianese R et al. | Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis. | 2014 | Gen. Comp. Endocrinol. | pmid:24566122 |
| Rea K et al. | Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. | 2014 | Eur. J. Neurosci. | pmid:24494683 |
| Zheng Y et al. | Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. | 2014 | Eur. J. Pharmacol. | pmid:24508383 |
| Al Kury LT et al. | Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. | 2014 | Cell Calcium | pmid:24472666 |
| Björklund E et al. | Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations. | 2014 | PLoS ONE | pmid:24466356 |
| Yu S et al. | Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in the brain. | 2014 | J. Biol. Chem. | pmid:24644281 |
| Mahavadi S et al. | Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24407588 |
| Jackson AR et al. | Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1. | 2014 | J. Leukoc. Biol. | pmid:24319288 |
| Okura D et al. | The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. | 2014 | Anesth. Analg. | pmid:24557103 |