Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Di Scala C et al. | Ceramide binding to anandamide increases its half-life and potentiates its cytotoxicity in human neuroblastoma cells. | 2017 | Chem. Phys. Lipids | pmid:28389107 |
Bondarenko AI et al. | Direct activation of Ca and voltage-gated potassium channels of large conductance by anandamide in endothelial cells does not support the presence of endothelial atypical cannabinoid receptor. | 2017 | Eur. J. Pharmacol. | pmid:28327344 |
Cui N et al. | Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin. | 2017 | Clin Ther | pmid:28291580 |
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Thompson Z et al. | Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. | 2017 | Physiol. Behav. | pmid:28017680 |
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Maia J et al. | The endocannabinoid system expression in the female reproductive tract is modulated by estrogen. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:28743542 |
Karlsson J et al. | Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. | 2017 | PLoS ONE | pmid:28910408 |
Murtaza G et al. | TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries. | 2017 | PLoS ONE | pmid:28301582 |
Smaga I et al. | Changes in the Brain Endocannabinoid System in Rat Models of Depression. | 2017 | Neurotox Res | pmid:28247204 |
Quartu M et al. | Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. | 2017 | Lipids Health Dis | pmid:28103941 |
Bruijnzeel AW et al. | Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats. | 2016 | PLoS ONE | pmid:27065006 |
Walker VJ et al. | Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes. | 2016 | J. Pharmacol. Exp. Ther. | pmid:27000802 |
Limebeer CL et al. | Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model. | 2016 | Behav. Neurosci. | pmid:26974857 |
Demers CH et al. | Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions. | 2016 | Biol. Psychiatry | pmid:26923505 |
Wang X et al. | Circulating Endocannabinoids and Insulin Resistance in Patients with Obstructive Sleep Apnea. | 2016 | Biomed Res Int | pmid:26904688 |
Sun X et al. | Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. | 2016 | J. Biol. Chem. | pmid:26900150 |
Kangas BD et al. | Comparisons of Δ9-Tetrahydrocannabinol and Anandamide on a Battery of Cognition-Related Behavior in Nonhuman Primates. | 2016 | J. Pharmacol. Exp. Ther. | pmid:26826191 |
Schindler CW et al. | Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys. | 2016 | Psychopharmacology (Berl.) | pmid:26803499 |
González-Mariscal I et al. | Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice. | 2016 | Mol. Cell. Endocrinol. | pmid:26724516 |
Ma C et al. | Anti-carcinogenic activity of anandamide on human glioma in vitro and in vivo. | 2016 | Mol Med Rep | pmid:26707955 |
Lu HC and Mackie K | An Introduction to the Endogenous Cannabinoid System. | 2016 | Biol. Psychiatry | pmid:26698193 |
Panlilio LV et al. | Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. | 2016 | Psychopharmacology (Berl.) | pmid:26558620 |
Kudalkar SN et al. | Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. | 2016 | Methods Mol. Biol. | pmid:27245906 |
Kerr DM et al. | Pharmacological inhibition of fatty acid amide hydrolase attenuates social behavioural deficits in male rats prenatally exposed to valproic acid. | 2016 | Pharmacol. Res. | pmid:27592249 |
Doenni VM et al. | Deficient adolescent social behavior following early-life inflammation is ameliorated by augmentation of anandamide signaling. | 2016 | Brain Behav. Immun. | pmid:27453335 |
Morena M et al. | Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. | 2016 | Neuropharmacology | pmid:27553121 |
Veeraraghavan P et al. | A study of cannabinoid-1 receptors during the early phase of excitotoxic damage to rat spinal locomotor networks in vitro. | 2016 | Neuroscience | pmid:27450568 |
van Zadelhoff G and van der Stelt M | Oxygenation of Anandamide by Lipoxygenases. | 2016 | Methods Mol. Biol. | pmid:27245907 |
Grambow E et al. | Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity. | 2016 | Biofactors | pmid:27151562 |
Martella A et al. | Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop. | 2016 | Endocrinology | pmid:27014939 |
Iannotti FA et al. | Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. | 2016 | Prog. Lipid Res. | pmid:26965148 |
Rajaraman G et al. | G protein coupled receptor 18: A potential role for endocannabinoid signaling in metabolic dysfunction. | 2016 | Mol Nutr Food Res | pmid:26337420 |
Jacome-Sosa M et al. | Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat. | 2016 | J. Lipid Res. | pmid:26891736 |
Leishman E et al. | Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. | 2016 | Biochim. Biophys. Acta | pmid:26956082 |
Malek N et al. | The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain. | 2016 | Pharmacol. Res. | pmid:27326920 |
Martin GG et al. | FABP-1 gene ablation impacts brain endocannabinoid system in male mice. | 2016 | J. Neurochem. | pmid:27167970 |