Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kukushkin ML et al. | Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. | 2006 | Bull. Exp. Biol. Med. | pmid:17369898 |
| Szabo B et al. | Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol. | 2006 | J. Physiol. (Lond.) | pmid:16973696 |
| Wiley JL et al. | Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. | 2006 | Life Sci. | pmid:16978656 |
| Thors L and Fowler CJ | Is there a temperature-dependent uptake of anandamide into cells? | 2006 | Br. J. Pharmacol. | pmid:16865094 |
| Nilsson O et al. | The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells. | 2006 | Eur. J. Pharmacol. | pmid:16928371 |
| Schuel H | Tuning the oviduct to the anandamide tone. | 2006 | J. Clin. Invest. | pmid:16886056 |
| Kasai HF et al. | Studies on high-energy collision-induced dissociation of endogenous cannabinoids: 2-arachidonoylglycerol and n-arachidonoylethanolamide in FAB-mass spectrometry. | 2006 | Anal Sci | pmid:16837740 |
| Murillo-RodrÃguez E et al. | Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. | 2006 | FEBS Lett. | pmid:16844117 |
| Liu J et al. | A biosynthetic pathway for anandamide. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16938887 |
| Mechoulam R et al. | Endocannabinoids, feeding and suckling--from our perspective. | 2006 | Int J Obes (Lond) | pmid:16570101 |
| Matias I et al. | Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. | 2006 | Int J Obes (Lond) | pmid:16570107 |
| Schiano Moriello A et al. | Development of the first potential covalent inhibitors of anandamide cellular uptake. | 2006 | J. Med. Chem. | pmid:16570928 |
| Kudo R and Hatake K | [Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation]. | 2006 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:17313058 |
| Appendino G et al. | Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. | 2006 | J. Med. Chem. | pmid:16570929 |
| Chang L et al. | Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. | 2006 | Br. J. Pharmacol. | pmid:16501580 |
| Guagnini F et al. | Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. | 2006 | Gut | pmid:16423891 |
| Meuth SG et al. | The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. | 2006 | Mol. Pharmacol. | pmid:16424077 |
| Marx J | Drug development. Drugs inspired by a drug. | 2006 | Science | pmid:16424309 |
| Cupini LM et al. | Biochemical changes in endocannabinoid system are expressed in platelets of female but not male migraineurs. | 2006 | Cephalalgia | pmid:16472333 |
| GarcÃa Mdel C et al. | Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. | 2006 | Eur. J. Pharmacol. | pmid:16472800 |
| Romano MR and Lograno MD | Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels. | 2006 | Br. J. Pharmacol. | pmid:16474412 |
| Tuccinardi T et al. | Cannabinoid CB2/CB1 selectivity. Receptor modeling and automated docking analysis. | 2006 | J. Med. Chem. | pmid:16451064 |
| Monterrubio S and Solowij N | Chronic stress and adaptation. | 2006 | Am J Psychiatry | pmid:16513893 |
| Bari M et al. | New insights into endocannabinoid degradation and its therapeutic potential. | 2006 | Mini Rev Med Chem | pmid:16515464 |
| Overton HA et al. | Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. | 2006 | Cell Metab. | pmid:16517404 |
| Matias I et al. | Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011761 |
| Bari M et al. | Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. | 2006 | J. Immunol. | pmid:17015679 |
| Tan B et al. | Targeted lipidomics: discovery of new fatty acyl amides. | 2006 | AAPS J | pmid:17025263 |
| Guindon J et al. | Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | 2006 | Eur. J. Pharmacol. | pmid:17027744 |
| Prestifilippo JP et al. | Inhibition of salivary secretion by activation of cannabinoid receptors. | 2006 | Exp. Biol. Med. (Maywood) | pmid:16946411 |
| Spoto B et al. | Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. | 2006 | Biochimie | pmid:16949718 |
| Vlachou S et al. | Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. | 2006 | Psychopharmacology (Berl.) | pmid:16953388 |
| Mulder AM and Cravatt BF | Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines. | 2006 | Biochemistry | pmid:16981687 |
| De Lago E et al. | Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. | 2006 | J. Neurochem. | pmid:16899063 |
| Laezza C et al. | Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. | 2006 | FEBS Lett. | pmid:17055492 |
| Gough NR | Focus issue: signaling lipids. | 2006 | Sci. STKE | pmid:16467192 |
| Migliarini B et al. | Endocannabinoid system in Xenopus laevis development: CB1 receptor dynamics. | 2006 | FEBS Lett. | pmid:16519888 |
| Wang J et al. | Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family. | 2006 | J. Biol. Chem. | pmid:16527816 |
| Bortolato M et al. | Anxiolytic-like properties of the anandamide transport inhibitor AM404. | 2006 | Neuropsychopharmacology | pmid:16541083 |
| Maccarrone M et al. | Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. | 2006 | Thromb. Haemost. | pmid:16543970 |
| Siegmund SV et al. | Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. | 2006 | J. Biol. Chem. | pmid:16418162 |
| Salo OM et al. | 3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data. | 2006 | J. Med. Chem. | pmid:16420041 |
| Kohro S et al. | Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis. | 2006 | J Anesth | pmid:16421670 |
| Rawls SM et al. | Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. | 2006 | Pharmacol. Biochem. Behav. | pmid:16647109 |
| Parkkari T et al. | Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide. | 2006 | Bioorg. Med. Chem. | pmid:16644227 |
| McFarland MJ et al. | Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. | 2006 | AAPS J | pmid:16584138 |
| Varvel SA et al. | Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16352706 |
| Giuliano M et al. | Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. | 2006 | Int. J. Mol. Med. | pmid:16596265 |
| Di Marzo M et al. | Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. | 2006 | J. Pept. Sci. | pmid:16534762 |
| Cobellis G et al. | Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. | 2006 | Biol. Reprod. | pmid:16611862 |
| Solinas M et al. | Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats. | 2006 | J. Neurochem. | pmid:16805835 |
| Wei BQ et al. | A second fatty acid amide hydrolase with variable distribution among placental mammals. | 2006 | J. Biol. Chem. | pmid:17015445 |
| Rösch S et al. | R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16330497 |
| Zaniewska M et al. | Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats. | 2006 | Eur. J. Pharmacol. | pmid:16730696 |
| Harada N et al. | Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats. | 2006 | Thromb. Haemost. | pmid:16732381 |
| van der Stelt M et al. | Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. | 2006 | Cell. Mol. Life Sci. | pmid:16732431 |
| Sade H et al. | Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids. | 2006 | Am. J. Physiol., Cell Physiol. | pmid:16107501 |
| Fisyunov A et al. | Cannabinoids modulate the P-type high-voltage-activated calcium currents in purkinje neurons. | 2006 | J. Neurophysiol. | pmid:16738209 |
| Vogeser M et al. | Release of anandamide from blood cells. | 2006 | Clin. Chem. Lab. Med. | pmid:16599845 |
| Kopczyńska B and Szereda-Przestaszewska M | Supranodose vagotomy eliminates anandamide-evoked cardiorespiratory depression in anaesthetized rats. | 2006 | Respir Physiol Neurobiol | pmid:16144778 |
| Wang H et al. | Fatty acid amide hydrolase deficiency limits early pregnancy events. | 2006 | J. Clin. Invest. | pmid:16886060 |
| Tzavara ET et al. | Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. | 2006 | Biol. Psychiatry | pmid:16199010 |
| Schmidt A et al. | Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. | 2006 | Biomed. Chromatogr. | pmid:16189813 |
| Wiles AL et al. | N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a. | 2006 | J. Neurochem. | pmid:16899062 |
| Juan-Picó P et al. | Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. | 2006 | Cell Calcium | pmid:16321437 |
| Cannizzaro C et al. | Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus. | 2006 | Neurochem. Int. | pmid:16325966 |
| Lizanecz E et al. | Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1. | 2006 | Mol. Pharmacol. | pmid:16338989 |
| Moezi L et al. | Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors. | 2006 | Br. J. Pharmacol. | pmid:17043671 |
| Grimaldi C et al. | Anandamide inhibits adhesion and migration of breast cancer cells. | 2006 | Exp. Cell Res. | pmid:16343481 |
| Eljaschewitsch E et al. | The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. | 2006 | Neuron | pmid:16387640 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Yang YY et al. | Roles of anandamide in the hepatic microcirculation in cirrhotic rats. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16407591 |
| Glaser ST et al. | Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16278311 |
| Appendino G et al. | First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands. | 2006 | FEBS Lett. | pmid:16406364 |
| Glaser ST et al. | Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. | 2005 Nov-Dec | Vis. Neurosci. | pmid:16469181 |
| Abalo R et al. | Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. | 2005 Jul 22-29 | Neurosci. Lett. | pmid:15936532 |
| Kurabayashi M et al. | 2-Arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver. | 2005 Jan-Feb | J Invest Surg | pmid:15804949 |
| Basavarajappa BS and Hungund BL | Role of the endocannabinoid system in the development of tolerance to alcohol. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550443 |
| RodrÃguez de Fonseca F et al. | The endocannabinoid system: physiology and pharmacology. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550444 |
| Price TJ et al. | A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons. | 2005 | Neuropharmacology | pmid:15992578 |
| Taddei S | Evolving the concept of regulation of vascular tone in humans. | 2005 | Br. J. Pharmacol. | pmid:15997231 |
| Hohmann AG et al. | An endocannabinoid mechanism for stress-induced analgesia. | 2005 | Nature | pmid:15973410 |
| Glaser ST et al. | Anandamide transport: a critical review. | 2005 | Life Sci. | pmid:15979096 |
| Ambrosi S et al. | On the importance of anandamide structural features for its interactions with DPPC bilayers: effects on PLA2 activity. | 2005 | J. Lipid Res. | pmid:15961786 |
| Tian X et al. | The conformation, location, and dynamic properties of the endocannabinoid ligand anandamide in a membrane bilayer. | 2005 | J. Biol. Chem. | pmid:15964843 |
| Wiley JL et al. | Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. | 2005 | Eur. J. Pharmacol. | pmid:15740725 |
| Matsuda K et al. | The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. | 2005 | Tohoku J. Exp. Med. | pmid:16141678 |
| Suplita RL et al. | Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. | 2005 | Neuropharmacology | pmid:16129456 |
| Osei-Hyiaman D et al. | Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. | 2005 | Neuroendocrinology | pmid:16131814 |
| Mechoulam R and Deutsch DG | Toward an anandamide transporter. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16314567 |
| Ligresti A et al. | Endocannabinoid metabolic pathways and enzymes. | 2005 | Curr Drug Targets CNS Neurol Disord | pmid:16375679 |
| Flygare J et al. | Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. | 2005 | FEBS Lett. | pmid:16337199 |
| Sarnataro D et al. | Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells. | 2005 | FEBS Lett. | pmid:16263116 |
| Van Sickle MD et al. | Identification and functional characterization of brainstem cannabinoid CB2 receptors. | 2005 | Science | pmid:16224028 |
| Besana A et al. | Lipids and two-pore domain K+ channels in excitable cells. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099395 |
| van der Stelt M and Di Marzo V | Anandamide as an intracellular messenger regulating ion channel activity. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099396 |
| Patsos HA et al. | The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2. | 2005 | Gut | pmid:16099783 |
| Yoshihara S et al. | Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. | 2005 | Int. Arch. Allergy Immunol. | pmid:16103691 |
| van der Stelt M et al. | Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. | 2005 | EMBO J. | pmid:16107881 |
| Lynch DL and Reggio PH | Molecular dynamics simulations of the endocannabinoid N-arachidonoylethanolamine (anandamide) in a phospholipid bilayer: probing structure and dynamics. | 2005 | J. Med. Chem. | pmid:16033262 |