Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Neuroblastoma D009447 66 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Nervous System Diseases D009422 37 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Hepatitis D006505 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Grainger J and Boachie-Ansah G Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. 2001 Br. J. Pharmacol. pmid:11682448
Farquhar-Smith WP and Rice AS Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. 2001 Anesthesiology pmid:11374613
Christopoulos A and Wilson K Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. 2001 Brain Res. pmid:11578621
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
Mendizábal VE et al. Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. 2001 Eur. J. Pharmacol. pmid:11567656
Baker D et al. Endocannabinoids control spasticity in a multiple sclerosis model. 2001 FASEB J. pmid:11156943
Gauldie SD et al. Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. 2001 Br. J. Pharmacol. pmid:11159713
Tognetto M et al. Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. 2001 J. Neurosci. pmid:11160380
MacCarrone M et al. Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. 2001 Eur. J. Biochem. pmid:11168423
Hayase T et al. Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. 2001 Nihon Arukoru Yakubutsu Igakkai Zasshi pmid:11828716
Deutsch DG et al. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. 2001 J. Biol. Chem. pmid:11118429
De Petrocellis L et al. The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. 2001 J. Biol. Chem. pmid:11278420
Jacobsson SO and Fowler CJ Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. 2001 Br. J. Pharmacol. pmid:11309246
Quistad GB et al. Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. 2001 Toxicol. Appl. Pharmacol. pmid:11350214
Möhle R et al. Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. 2001 Ann. N. Y. Acad. Sci. pmid:11458515
Wallace MJ et al. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. 2002 Eur. J. Pharmacol. pmid:12359270
Roberts LA et al. Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons. 2002 Br. J. Pharmacol. pmid:12359623
Oz M et al. Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes. 2002 Synapse pmid:12325042
Ralevic V et al. Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function. 2002 Life Sci. pmid:12354577
Laine K et al. Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid. 2002 Invest. Ophthalmol. Vis. Sci. pmid:12356827
Barthó L et al. Nitric oxide is involved in the relaxant effect of capsaicin in the human sigmoid colon circular muscle. 2002 Naunyn Schmiedebergs Arch. Pharmacol. pmid:12382081
Milton NG Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. 2002 Neurosci. Lett. pmid:12384227
Krylatov AV et al. Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. 2002 Bull. Exp. Biol. Med. pmid:12428277
Plant LD et al. Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. 2002 Stroke pmid:12215606
Anikwue R et al. Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration. 2002 J. Pharmacol. Exp. Ther. pmid:12235269
Rueda D et al. The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway. 2002 J. Biol. Chem. pmid:12237305
Schmid PC et al. Anandamide and other N-acylethanolamines in human tumors. 2002 Lipids pmid:12458627
Harris D et al. Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. 2002 J. Physiol. (Lond.) pmid:11897858
Lin YS and Lee LY Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors. 2002 J. Physiol. (Lond.) pmid:11897863
Walter L et al. Astrocytes in culture produce anandamide and other acylethanolamides. 2002 J. Biol. Chem. pmid:11916961
Begg M et al. Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum. 2002 Eur. J. Pharmacol. pmid:11755170
Ros J et al. Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. 2002 Gastroenterology pmid:11781284
Lever IJ and Malcangio M CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. 2002 Br. J. Pharmacol. pmid:11786475
Molderings GJ et al. Noradrenaline release-inhibiting receptors on PC12 cells devoid of alpha(2(-)) and CB(1) receptors: similarities to presynaptic imidazoline and edg receptors. 2002 Neurochem. Int. pmid:11738482
Matias I et al. Presence and regulation of the endocannabinoid system in human dendritic cells. 2002 Eur. J. Biochem. pmid:12153574
Schäbitz WR et al. Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study. 2002 Stroke pmid:12154273
Costa B et al. Chronic treatment with the endocannabinoid anandamide increases cytochrome P450 metabolizing system in the rat. 2002 Eur. J. Pharmacol. pmid:12163107
de Lago E et al. UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide. 2002 Eur. J. Pharmacol. pmid:12163112
Andersson DA et al. Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists. 2002 Mol. Pharmacol. pmid:12181448
Goutopoulos A and Makriyannis A From cannabis to cannabinergics: new therapeutic opportunities. 2002 Pharmacol. Ther. pmid:12182958
Hansen HS et al. Putative neuroprotective actions of N-acyl-ethanolamines. 2002 Pharmacol. Ther. pmid:12182959
Randall MD et al. Cardiovascular effects of cannabinoids. 2002 Pharmacol. Ther. pmid:12182966
Kagaya M et al. Characterization of the anandamide induced depolarization of guinea-pig isolated vagus nerve. 2002 Br. J. Pharmacol. pmid:12183329
Ishii I and Chun J Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors. 2002 Neuroreport pmid:11973452
Gerdeman GL et al. Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. 2002 Nat. Neurosci. pmid:11976704
Gardiner SM et al. Complex regional haemodynamic effects of anandamide in conscious rats. 2002 Br. J. Pharmacol. pmid:11959791
Jerman JC et al. Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors. 2002 Br J Anaesth pmid:12453933
Romero J et al. Fatty acid amide hydrolase localization in the human central nervous system: an immunohistochemical study. 2002 Brain Res. Mol. Brain Res. pmid:12008024
Jia Y et al. Anandamide induces cough in conscious guinea-pigs through VR1 receptors. 2002 Br. J. Pharmacol. pmid:12411414
Geraghty DP and Mazzone SB Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. 2002 Br. J. Pharmacol. pmid:12411424