Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gubellini P et al. | Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. | 2002 | J. Neurosci. | pmid:12177188 |
| Mechoulam R | Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052029 |
| Sugiura T et al. | Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052034 |
| Fowler CJ and Jacobsson SO | Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052035 |
| Deutsch DG et al. | The fatty acid amide hydrolase (FAAH). | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052036 |
| Fride E | Endocannabinoids in the central nervous system--an overview. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052038 |
| Pinto L et al. | Endocannabinoids and the gut. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052047 |
| Högestätt ED and Zygmunt PM | Cardiovascular pharmacology of anandamide. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052048 |
| Di Marzo V et al. | Anandamide receptors. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052051 |
| van der Stelt M et al. | Acute neuronal injury, excitotoxicity, and the endocannabinoid system. | 2002 Oct-Dec | Mol. Neurobiol. | pmid:12428763 |
| Nilsson O et al. | Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures. | 2003 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:14659458 |
| Vandevoorde S et al. | Esters, retroesters, and a retroamide of palmitic acid: pool for the first selective inhibitors of N-palmitoylethanolamine-selective acid amidase. | 2003 | J. Med. Chem. | pmid:14521402 |
| Fowler CJ et al. | Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. | 2003 | Biochem. Pharmacol. | pmid:12948856 |
| Wilson SJ et al. | A high-throughput-compatible assay for determining the activity of fatty acid amide hydrolase. | 2003 | Anal. Biochem. | pmid:12814631 |
| Maccarrone M et al. | The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activation protein-1, and transglutaminase. | 2003 | J. Biol. Chem. | pmid:12815050 |
| Obata T et al. | Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:12829006 |
| Nicholson RA et al. | Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. | 2003 | Brain Res. | pmid:12834914 |
| Perrier JF et al. | 5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle. | 2003 | J. Physiol. (Lond.) | pmid:12626670 |
| Maccarrone M et al. | Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. | 2003 | J. Biol. Chem. | pmid:12799380 |
| Ahluwalia J et al. | Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro. | 2003 | Eur. J. Neurosci. | pmid:12823468 |
| El Fangour S et al. | Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12781177 |
| Tarzia G et al. | Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. | 2003 | J. Med. Chem. | pmid:12773040 |
| Sokal DM et al. | Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. | 2003 | Neuropharmacology | pmid:12871657 |
| Hillard CJ and Jarrahian A | Cellular accumulation of anandamide: consensus and controversy. | 2003 | Br. J. Pharmacol. | pmid:12970089 |
| Cravatt BF and Lichtman AH | Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. | 2003 | Curr Opin Chem Biol | pmid:12941421 |
| Helyes Z et al. | Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat. | 2003 | Life Sci. | pmid:12941436 |
| Franklin A et al. | Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. | 2003 | J. Neurosci. | pmid:12944505 |
| Liu J et al. | Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. | 2003 | J. Biol. Chem. | pmid:12949078 |
| del Carmen GarcÃa M et al. | Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14504685 |
| McVey DC et al. | Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). | 2003 | J. Pharmacol. Exp. Ther. | pmid:12538826 |
| Scorticati C et al. | The effect of anandamide on prolactin secretion is modulated by estrogen. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12578974 |
| Ahluwalia J et al. | Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release. | 2003 | J. Neurochem. | pmid:12558978 |
| Sancho R et al. | Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. | 2003 | Mol. Pharmacol. | pmid:12527815 |
| Jennings EA et al. | The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. | 2003 | J. Physiol. (Lond.) | pmid:12562891 |
| Randall MD | A new endothelial target for cannabinoids. | 2003 | Mol. Pharmacol. | pmid:12606752 |
| Wisnoskey BJ et al. | Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry. | 2003 | Biochem. J. | pmid:12608892 |
| Vandevoorde S et al. | N-Morpholino- and N-diethyl-analogues of palmitoylethanolamide increase the sensitivity of transfected human vanilloid receptors to activation by anandamide without affecting fatty acid amidohydrolase activity. | 2003 | Bioorg. Med. Chem. | pmid:12614867 |
| Lau AH and Chow SS | Effects of cannabinoid receptor agonists on immunologically induced histamine release from rat peritoneal mast cells. | 2003 | Eur. J. Pharmacol. | pmid:12620517 |
| Maccarrone M et al. | Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. | 2003 | Endocrinology | pmid:12488326 |
| Orliac ML et al. | Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12490589 |
| Schelegle ES | Functional morphology and physiology of slowly adapting pulmonary stretch receptors. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494485 |
| Lee LY et al. | Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494486 |
| Higgs S et al. | Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. | 2003 | Psychopharmacology (Berl.) | pmid:12447606 |
| Sarker KP and Maruyama I | Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts. | 2003 | Cell. Mol. Life Sci. | pmid:12861385 |
| Bojesen IN and Hansen HS | Binding of anandamide to bovine serum albumin. | 2003 | J. Lipid Res. | pmid:12837852 |
| Patel S et al. | The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. | 2003 | Br. J. Pharmacol. | pmid:12839875 |
| Watanabe H et al. | Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. | 2003 | Nature | pmid:12879072 |
| Kozak KR et al. | Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide. | 2003 | Biochemistry | pmid:12885237 |
| Costanzi M et al. | Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. | 2003 | Neurobiol Learn Mem | pmid:12676519 |
| Fowler CJ et al. | Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin. | 2003 | J Enzyme Inhib Med Chem | pmid:14506913 |