Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lobato NS et al. | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. | 2013 | PLoS ONE | pmid:23667622 |
Marichal-Cancino BA et al. | Analysis of anandamide- and lysophosphatidylinositol-induced inhibition of the vasopressor responses produced by sympathetic stimulation or noradrenaline in pithed rats. | 2013 | Eur. J. Pharmacol. | pmid:24076186 |
Feuerecker M et al. | Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humans. | 2012 May-Jun | Alcohol Alcohol. | pmid:22278319 |
Hutchins-Wiese HL et al. | Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle. | 2012 | J. Nutr. Biochem. | pmid:22051448 |
Heyman E et al. | Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. | 2012 | Psychoneuroendocrinology | pmid:22029953 |
Izumi Y and Zorumski CF | NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. | 2012 | Neuropsychopharmacology | pmid:21993209 |
Malinowska B et al. | Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? | 2012 | Br. J. Pharmacol. | pmid:22022923 |
Forsell PK et al. | Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. | 2012 | Lipids | pmid:22684912 |
Jarzimski C et al. | Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? | 2012 | Br J Clin Pharmacol | pmid:22242687 |
Umathe SN et al. | Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor. | 2012 | Neuropharmacology | pmid:22248639 |
Newberry EP et al. | Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice. | 2012 | J. Lipid Res. | pmid:22327204 |
Zhang X et al. | Agonist-dependent potentiation of vanilloid receptor transient receptor potential vanilloid type 1 function by stilbene derivatives. | 2012 | Mol. Pharmacol. | pmid:22328719 |
Rogers TJ | The molecular basis for neuroimmune receptor signaling. | 2012 | J Neuroimmune Pharmacol | pmid:22935971 |
Rajesh M et al. | Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. | 2012 | Diabetes | pmid:22315315 |
Shi RZ et al. | Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II. | 2012 | Eur. J. Pharmacol. | pmid:22318155 |
Battista N et al. | The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. | 2012 | Mol. Cell. Endocrinol. | pmid:22305972 |
Liu J et al. | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Gastroenterology | pmid:22307032 |
Fowler CJ | Anandamide uptake explained? | 2012 | Trends Pharmacol. Sci. | pmid:22297258 |
Izzo AA et al. | Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. | 2012 | Br. J. Pharmacol. | pmid:22300105 |
Chon SH et al. | Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. | 2012 | PLoS ONE | pmid:22937137 |
Brown WH et al. | Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22912404 |
Schreiber AK et al. | Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. | 2012 | Neuropharmacology | pmid:22959964 |
Lowin T et al. | Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system. | 2012 | Arthritis Rheum. | pmid:22933357 |
Alhouayek M and Muccioli GG | The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. | 2012 | Trends Mol Med | pmid:22917662 |
Thomas KC et al. | Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21949157 |
Li Q et al. | Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22173869 |
Stock K et al. | Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. | 2012 | Nat. Med. | pmid:22820645 |
Jang Y et al. | Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. | 2012 | J. Biol. Chem. | pmid:22187434 |
Marsicano G and Chaouloff F | Moving bliss: a new anandamide transporter. | 2012 | Nat. Neurosci. | pmid:22193249 |
Battista N et al. | Abnormal anandamide metabolism in celiac disease. | 2012 | J. Nutr. Biochem. | pmid:22209002 |
Schulte K et al. | Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22215206 |
Wu X et al. | Alteration of endocannabinoid system in human gliomas. | 2012 | J. Neurochem. | pmid:22176552 |
Starowicz K et al. | Spinal anandamide produces analgesia in neuropathic rats: possible CB(1)- and TRPV1-mediated mechanisms. | 2012 | Neuropharmacology | pmid:22178705 |
Harvey BS et al. | Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. | 2012 | Neurotoxicology | pmid:22233683 |
Gatta-Cherifi B et al. | Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity. | 2012 | Int J Obes (Lond) | pmid:21844878 |
Willibald J et al. | Click-modified anandamide siRNA enables delivery and gene silencing in neuronal and immune cells. | 2012 | J. Am. Chem. Soc. | pmid:22812910 |
Leweke FM | Anandamide dysfunction in prodromal and established psychosis. | 2012 | Curr. Pharm. Des. | pmid:22716147 |
Wang ZJ et al. | Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. | 2012 | J. Neurosci. | pmid:22723687 |
Neelamegan D et al. | Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. | 2012 | BMC Microbiol. | pmid:22730904 |
Moreno-Sanz G et al. | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. | 2012 | Br. J. Pharmacol. | pmid:22774772 |
Rettori E et al. | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. | 2012 | Neuroimmunomodulation | pmid:22777139 |
Luchicchi A and Pistis M | Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids. | 2012 | Mol. Neurobiol. | pmid:22801993 |
Krishnan G and Chatterjee N | Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation. | 2012 | Glia | pmid:22807196 |
Romano MR and Lograno MD | Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery. | 2012 | Eur. J. Pharmacol. | pmid:22429572 |
Xiong W et al. | A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. | 2012 | J. Neurosci. | pmid:22496565 |
Kenessey I et al. | Revisiting CB1 receptor as drug target in human melanoma. | 2012 | Pathol. Oncol. Res. | pmid:22447182 |
Petrovszki Z et al. | The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. | 2012 | Anesth. Analg. | pmid:22451592 |
Tamaki C et al. | Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed. | 2012 | J. Pharmacol. Sci. | pmid:22510966 |
Czifra G et al. | Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. | 2012 | J. Invest. Dermatol. | pmid:22513781 |
Miller LL et al. | Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514333 |
Caprioli A et al. | The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514334 |
Ritter JK et al. | Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22685343 |
Gebeh AK et al. | Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22701012 |
Chianese R et al. | Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22669247 |
Chicca A et al. | The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. | 2012 | Br. J. Pharmacol. | pmid:22646533 |
Hernangómez M et al. | CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. | 2012 | Glia | pmid:22653796 |
Tsumura M et al. | TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. | 2012 | Cell Calcium | pmid:22656960 |
Fogaça MV et al. | Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. | 2012 | Braz. J. Med. Biol. Res. | pmid:22392189 |
Lisboa SF and Guimarães FS | Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. | 2012 | Neuropharmacology | pmid:22394688 |
Manna SS and Umathe SN | Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures. | 2012 | Epilepsy Res. | pmid:22386872 |
Lara-Celador I et al. | Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats. | 2012 | Brain Res. | pmid:22841538 |
Kaczocha M et al. | Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. | 2012 | ACS Chem Neurosci | pmid:22860204 |
Tanveer R et al. | The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. | 2012 | J. Biol. Chem. | pmid:22891244 |
Chicca A et al. | Evidence for bidirectional endocannabinoid transport across cell membranes. | 2012 | J. Biol. Chem. | pmid:22879589 |
Leweke FM et al. | Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | 2012 | Transl Psychiatry | pmid:22832859 |
Méndez-DÃaz M et al. | The endocannabinoid system modulates the valence of the emotion associated to food ingestion. | 2012 | Addict Biol | pmid:21182571 |
De Petrocellis L et al. | A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. | 2012 | Br. J. Pharmacol. | pmid:22861649 |
Whyte LS et al. | Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro. | 2012 | Br. J. Pharmacol. | pmid:21649637 |
Pamplona FA and Takahashi RN | Psychopharmacology of the endocannabinoids: far beyond anandamide. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21652605 |
Berger WT et al. | Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. | 2012 | PLoS ONE | pmid:23236415 |
Kuc C et al. | Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. | 2012 | Mol. Carcinog. | pmid:21432910 |
Proto MC et al. | Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. | 2012 | J. Cell. Physiol. | pmid:21412772 |
Skaper SD and Di Marzo V | Endocannabinoids in nervous system health and disease: the big picture in a nutshell. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108539 |
Di Marzo V and De Petrocellis L | Why do cannabinoid receptors have more than one endogenous ligand? | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108541 |
Puighermanal E et al. | Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108544 |
Starowicz K and Przewlocka B | Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108547 |
Rani Sagar D et al. | Dynamic changes to the endocannabinoid system in models of chronic pain. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108548 |
Campos AC et al. | Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108553 |
McHugh D et al. | Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. | 2012 | Br. J. Pharmacol. | pmid:21595653 |
Butti E et al. | Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity. | 2012 | Brain | pmid:23008234 |
Roa-Coria JE et al. | N-(4-Methoxy-2-nitrophenyl)hexadecanamide, a palmitoylethanolamide analogue, reduces formalin-induced nociception. | 2012 | Life Sci. | pmid:23069585 |
Schmidt W et al. | Cannabinoid receptor subtypes 1 and 2 mediate long-lasting neuroprotection and improve motor behavior deficits after transient focal cerebral ischemia. | 2012 | Neuroscience | pmid:23069763 |
Pastuhov SI et al. | Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. | 2012 | Nat Commun | pmid:23072806 |
Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
Lipina C et al. | New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. | 2012 | Bioessays | pmid:22674489 |
Fu J et al. | A catalytically silent FAAH-1 variant drives anandamide transport in neurons. | 2012 | Nat. Neurosci. | pmid:22101642 |
Feuerecker M et al. | Effects of exercise stress on the endocannabinoid system in humans under field conditions. | 2012 | Eur. J. Appl. Physiol. | pmid:22101870 |
Reyes-Cabello C et al. | Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. | 2012 | Pharmacol. Biochem. Behav. | pmid:22133635 |
Psychoyos D et al. | Cannabinoid receptor 1 signaling in embryo neurodevelopment. | 2012 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:22311661 |
Zoerner AA et al. | Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21752730 |
Sordelli MS et al. | Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. | 2012 | Eur. J. Pharmacol. | pmid:22554772 |
Roy A et al. | Anandamide modulates carotid sinus nerve afferent activity via TRPV1 receptors increasing responses to heat. | 2012 | J. Appl. Physiol. | pmid:21903882 |
Butler RK et al. | Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21926424 |
Khasabova IA et al. | Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. | 2012 | J. Neurosci. | pmid:22593077 |
Sun Y et al. | Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes. | 2012 | J. Pharmacol. Sci. | pmid:22293299 |
Edwards JG et al. | A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. | 2012 | Hippocampus | pmid:21069781 |
Haruta C | [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. | 2012 | Kokubyo Gakkai Zasshi | pmid:22568077 |
Katona I and Freund TF | Multiple functions of endocannabinoid signaling in the brain. | 2012 | Annu. Rev. Neurosci. | pmid:22524785 |
Tong S et al. | Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. | 2012 | Obstet Gynecol | pmid:22525911 |
Baranowska-Kuczko M et al. | Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. | 2012 | Pharmacol. Res. | pmid:22627170 |