Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Neuroblastoma D009447 66 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Nervous System Diseases D009422 37 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Hepatitis D006505 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Hunter SA and Burstein SH Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. 1997 Life Sci. pmid:9126878
Bisogno T et al. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. 1997 Biochem. Biophys. Res. Commun. pmid:9344854
Mechoulam R et al. Anandamide may mediate sleep induction. 1997 Nature pmid:9288961
Wiley JL et al. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. 1997 Pharmacol. Biochem. Behav. pmid:9408225
Randall MD et al. Comparative pharmacology of endothelium-derived hyperpolarizing factor and anandamide in rat isolated mesentery. 1997 Eur. J. Pharmacol. pmid:9314035
Di Tomaso E et al. Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. 1997 Adv. Exp. Med. Biol. pmid:9321973
White R and Hiley CR A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. 1997 Br. J. Pharmacol. pmid:9422801
Zygmunt PM et al. Studies on the effects of anandamide in rat hepatic artery. 1997 Br. J. Pharmacol. pmid:9422814
Jarrahian A and Hillard CJ Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9431821
Sasaki T and Chang MC N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. 1997 Life Sci. pmid:9365227
Randall MD and Kendall DA Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. 1997 Eur. J. Pharmacol. pmid:9369375
Burkey TH et al. Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. 1997 Eur. J. Pharmacol. pmid:9384246
Calignano A et al. Potentiation of anandamide hypotension by the transport inhibitor, AM404. 1997 Eur. J. Pharmacol. pmid:9389389
Bloom AS et al. Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. 1997 Neurochem. Res. pmid:9131634
Deutsch DG and Makriyannis A Inhibitors of anandamide breakdown. 1997 NIDA Res. Monogr. pmid:9260184
Yu M et al. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. 1997 J. Biol. Chem. pmid:9261124
Welch SP Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems. 1997 Drug Alcohol Depend pmid:9179505
van der Stelt M et al. Dioxygenation of N-linoleoyl amides by soybean lipoxygenase-1. 1997 FEBS Lett. pmid:9271222
Stefano GB et al. Morphine- and anandamide-stimulated nitric oxide production inhibits presynaptic dopamine release. 1997 Brain Res. pmid:9272829
Schmid PC et al. Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. 1997 Chem. Phys. Lipids pmid:9275307
Cadogan AK et al. Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum. 1997 J. Neurochem. pmid:9282935
Deutsch DG et al. Production and physiological actions of anandamide in the vasculature of the rat kidney. 1997 J. Clin. Invest. pmid:9294122
Kurahashi Y et al. Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9299394
Wenger T et al. Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. 1997 Biochem. Biophys. Res. Commun. pmid:9299434
Wenger T et al. The effects of prenatally administered endogenous cannabinoid on rat offspring. 1997 Pharmacol. Biochem. Behav. pmid:9300616
Hillard CJ et al. Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. 1997 J. Neurochem. pmid:9231721
Lake KD et al. Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. 1997 J. Pharmacol. Exp. Ther. pmid:9190833
Wenger T et al. Effects of anandamide on gestation in pregnant rats. 1997 Life Sci. pmid:9199480
Molina-Holgado F et al. Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. 1997 Neuroreport pmid:9223079
Willoughby KA et al. The biodisposition and metabolism of anandamide in mice. 1997 J. Pharmacol. Exp. Ther. pmid:9223560
Beltramo M et al. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. 1997 FEBS Lett. pmid:9091314
Thumser AE et al. A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. 1997 Biochem. Pharmacol. pmid:9065749
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
De Petrocellis L et al. Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9070224
Sheskin T et al. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. 1997 J. Med. Chem. pmid:9057852
Bisogno T et al. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. 1997 J. Biol. Chem. pmid:9013571
Fowler CJ et al. Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. 1997 Pharmacol. Toxicol. pmid:9060042
Salzet M et al. Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. 1997 J. Immunol. pmid:9548480
Calignano A et al. Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. 1997 Eur. J. Pharmacol. pmid:9537804
Hillard CJ and Campbell WB Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. 1997 J. Lipid Res. pmid:9458263
Berdyshev EV et al. Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. 1997 Eur. J. Pharmacol. pmid:9253958
Soderstrom K et al. Discovery of novel cannabinoid receptor ligands from diverse marine organisms. 1997 Adv. Exp. Med. Biol. pmid:9561107
Plane F et al. Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. 1997 Br. J. Pharmacol. pmid:9283682
Fowler CJ et al. Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. 1997 J. Pharmacol. Exp. Ther. pmid:9353392
Stark S et al. Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. 1997 Cell. Mol. Neurobiol. pmid:9353590
van der Stelt M et al. The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. 1997 FEBS Lett. pmid:9357990
Beltramo M et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. 1997 Science pmid:9262477
Valk P et al. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. 1997 Blood pmid:9269762
Fernández-Ruiz JJ et al. Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. 1997 Biochem. Pharmacol. pmid:9256167
Burkey RT and Nation JR (R)-methanandamide, but not anandamide, substitutes for delta 9-THC in a drug-discrimination procedure. 1997 Exp Clin Psychopharmacol pmid:9260067