Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sugiura T et al. | Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8573114 |
| di Tomaso E et al. | Brain cannabinoids in chocolate. | 1996 | Nature | pmid:8751435 |
| Cadas H et al. | Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. | 1996 | J. Neurosci. | pmid:8656287 |
| Kempe K et al. | Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. | 1996 | J. Biol. Chem. | pmid:8663381 |
| Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
| Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
| Cravatt BF et al. | Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. | 1996 | Nature | pmid:8900284 |
| Sugiura T et al. | N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. | 1996 | J Lipid Mediat Cell Signal | pmid:8906545 |
| Ueda N et al. | Enzymes for anandamide biosynthesis and metabolism. | 1996 | J Lipid Mediat Cell Signal | pmid:8906546 |
| Yang ZM et al. | Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. | 1996 | Biol. Reprod. | pmid:8879486 |
| Varga K et al. | Mechanism of the hypotensive action of anandamide in anesthetized rats. | 1996 | Hypertension | pmid:8843898 |
| Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
| Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
| Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
| Fride E and Mechoulam R | Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. | 1996 | Brain Res. Dev. Brain Res. | pmid:8873985 |
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| Boring DL et al. | Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931121 |
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| Paria BC et al. | The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. | 1996 | Mol. Reprod. Dev. | pmid:8914076 |
| Langstein J et al. | cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. | 1996 Jul-Aug | Res. Immunol. | pmid:8903105 |
| Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
| Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
| Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
| Hansen HS et al. | Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons. | 1997 | J. Neurochem. | pmid:9231736 |
| Castellano C et al. | The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. | 1997 | Behav Pharmacol | pmid:9832956 |
| Bloom AS et al. | Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. | 1997 | Neurochem. Res. | pmid:9131634 |
| Deutsch DG and Makriyannis A | Inhibitors of anandamide breakdown. | 1997 | NIDA Res. Monogr. | pmid:9260184 |
| Yu M et al. | Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. | 1997 | J. Biol. Chem. | pmid:9261124 |
| Welch SP | Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems. | 1997 | Drug Alcohol Depend | pmid:9179505 |
| van der Stelt M et al. | Dioxygenation of N-linoleoyl amides by soybean lipoxygenase-1. | 1997 | FEBS Lett. | pmid:9271222 |
| Stefano GB et al. | Morphine- and anandamide-stimulated nitric oxide production inhibits presynaptic dopamine release. | 1997 | Brain Res. | pmid:9272829 |
| Schmid PC et al. | Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. | 1997 | Chem. Phys. Lipids | pmid:9275307 |
| Seltzman HH et al. | Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. | 1997 | J. Med. Chem. | pmid:9357529 |
| Cadogan AK et al. | Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum. | 1997 | J. Neurochem. | pmid:9282935 |
| Deutsch DG et al. | Production and physiological actions of anandamide in the vasculature of the rat kidney. | 1997 | J. Clin. Invest. | pmid:9294122 |
| Kurahashi Y et al. | Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299394 |
| Wenger T et al. | Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299434 |
| Wenger T et al. | The effects of prenatally administered endogenous cannabinoid on rat offspring. | 1997 | Pharmacol. Biochem. Behav. | pmid:9300616 |
| Ryan WJ et al. | Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. | 1997 | J. Med. Chem. | pmid:9357528 |
| Bisogno T et al. | Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. | 1997 | J. Biol. Chem. | pmid:9013571 |
| Fowler CJ et al. | Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. | 1997 | Pharmacol. Toxicol. | pmid:9060042 |
| Salzet M et al. | Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. | 1997 | J. Immunol. | pmid:9548480 |
| Calignano A et al. | Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. | 1997 | Eur. J. Pharmacol. | pmid:9537804 |
| Pate DW et al. | Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. | 1997 | Pharm. Res. | pmid:9453062 |
| Hillard CJ and Campbell WB | Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. | 1997 | J. Lipid Res. | pmid:9458263 |
| Berdyshev EV et al. | Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. | 1997 | Eur. J. Pharmacol. | pmid:9253958 |
| Plane F et al. | Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. | 1997 | Br. J. Pharmacol. | pmid:9283682 |
| Brodkin J and Moerschbaecher JM | SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9316868 |
| Fernández-Ruiz JJ et al. | Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. | 1997 | Biochem. Pharmacol. | pmid:9256167 |
| Burkey RT and Nation JR | (R)-methanandamide, but not anandamide, substitutes for delta 9-THC in a drug-discrimination procedure. | 1997 | Exp Clin Psychopharmacol | pmid:9260067 |