Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alzheimer Disease D000544 76 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Romani R et al. Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? 2011 Biochimie pmid:21664223
Khanna IK and Alexander CW Fatty acid amide hydrolase inhibitors--progress and potential. 2011 CNS Neurol Disord Drug Targets pmid:21631410
Busquets-Garcia A et al. Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. 2011 Biol. Psychiatry pmid:21684528
Warzecha Z et al. Role of sensory nerves in gastroprotective effect of anandamide in rats. 2011 J. Physiol. Pharmacol. pmid:21673369
Sarmad S et al. Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. 2011 J. Neurochem. pmid:21375532
Ishiguro H et al. Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. 2011 Synapse pmid:20506567
Kawahara H et al. Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. 2011 Br. J. Pharmacol. pmid:21175570
De Petrocellis L et al. Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. 2011 Br. J. Pharmacol. pmid:21175579
Jumpertz R et al. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. 2011 J. Clin. Endocrinol. Metab. pmid:21177788
De Petrocellis L et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. 2011 Pharmacol. Res. pmid:21215315
Clugston RD et al. Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. 2011 J. Lipid Res. pmid:21856784
Dollery C Investigative clinical pharmacology. 2011 Clin. Pharmacol. Ther. pmid:21862965
Kopczyńska B et al. Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. 2011 Eur. J. Pharmacol. pmid:21756900
Yoshino H et al. Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. 2011 J. Physiol. (Lond.) pmid:21807615
Theile JW and Cummins TR Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide. 2011 Mol. Pharmacol. pmid:21788423
Khasabova IA et al. Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. 2011 Pharmacol. Res. pmid:21440630
Johannesson M et al. Cloning, purification and characterization of non-human primate 12/15-lipoxygenases. 2010 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:20106647
Ali AB and Todorova M Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. 2010 Eur. J. Neurosci. pmid:20345910
Frampton G et al. Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. 2010 Exp. Cell Res. pmid:20347808
Kim J and Alger BE Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. 2010 Nat. Neurosci. pmid:20348918
Hansen HS Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain. 2010 Exp. Neurol. pmid:20353771
Greco R et al. The endocannabinoid system and migraine. 2010 Exp. Neurol. pmid:20353780
Taylor AH et al. Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle. 2010 Histochem. Cell Biol. pmid:20369362
De Laurentiis A et al. The hypothalamic endocannabinoid system participates in the secretion of oxytocin and tumor necrosis factor-alpha induced by lipopolysaccharide. 2010 J. Neuroimmunol. pmid:20207018
Morera-Herreras T et al. Regulation of subthalamic neuron activity by endocannabinoids. 2010 Synapse pmid:20336631
Falenski KW et al. FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. 2010 Neuropsychopharmacology pmid:20357755
Soltys J et al. Regulation of neural progenitor cell fate by anandamide. 2010 Biochem. Biophys. Res. Commun. pmid:20691161
Bagavandoss P and Grimshaw S Temporal and spatial distribution of the cannabinoid receptors (CB1, CB2) and fatty acid amide hydroxylase in the rat ovary. 2010 Anat Rec (Hoboken) pmid:20665820
Bobbala D et al. Effect of anandamide in Plasmodium Berghei-infected mice. 2010 Cell. Physiol. Biochem. pmid:20798520
Tree K et al. Anandamide centrally depresses the respiratory rhythm generator of neonatal mice. 2010 Neuroscience pmid:20800658
Glaser ST and Kaczocha M Cyclooxygenase-2 mediates anandamide metabolism in the mouse brain. 2010 J. Pharmacol. Exp. Ther. pmid:20702753
Pratt-Hyatt M et al. Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide. 2010 Drug Metab. Dispos. pmid:20702771
Burdyga G et al. Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20430875
Hill MN et al. Endogenous cannabinoid signaling is essential for stress adaptation. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20439721
Ying-Ying Y and Lin HC Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. 2010 Liver Int. pmid:20408944
Spradley JM et al. Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. 2010 Pharmacol. Res. pmid:20416378
Placzek EA et al. Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). 2010 J Pharm Biomed Anal pmid:20417049
Massa F et al. Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. 2010 J. Neurosci. pmid:20445053
Oddi S et al. Pitfalls and solutions in assaying anandamide transport in cells. 2010 J. Lipid Res. pmid:20447929
Pisani V et al. Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients. 2010 Mov. Disord. pmid:20461809
Izzo AA and Sharkey KA Cannabinoids and the gut: new developments and emerging concepts. 2010 Pharmacol. Ther. pmid:20117132
Lerner TN et al. Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. 2010 J. Neurosci. pmid:20147543
Ueda N et al. N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). 2010 Prog. Lipid Res. pmid:20152858
Tanimura A et al. The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. 2010 Neuron pmid:20159446
Reggio PH Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown. 2010 Curr. Med. Chem. pmid:20166921
Di Marzo V and De Petrocellis L Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. 2010 Curr. Med. Chem. pmid:20166923
Solinas M et al. Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide. 2010 Psychopharmacology (Berl.) pmid:20179908
Rueda-Orozco PE et al. Intrahippocampal administration of anandamide increases REM sleep. 2010 Neurosci. Lett. pmid:20188142
Chávez AE et al. TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. 2010 Nat. Neurosci. pmid:21076423
Mukhopadhyay P et al. CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. 2010 Cardiovasc. Res. pmid:19942623