| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alzheimer Disease | D000544 | 76 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bisogno T et al. | Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. | 1998 | Eur. J. Biochem. | pmid:9688276 |
| Van Der Stelt M and Di Marzo V | Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. | 2004 | Eur. J. Biochem. | pmid:15128293 |
| MacCarrone M et al. | Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. | 2001 | Eur. J. Biochem. | pmid:11168423 |
| Fasia L et al. | Uptake and metabolism of [3H]anandamide by rabbit platelets. Lack of transporter? | 2003 | Eur. J. Biochem. | pmid:12919314 |
| Bisogno T et al. | The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. | 2001 | Eur. J. Biochem. | pmid:11277920 |
| Salzet M et al. | Comparative biology of the endocannabinoid system possible role in the immune response. | 2000 | Eur. J. Biochem. | pmid:10931174 |
| Sugiura T et al. | Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. | 1996 | Eur. J. Biochem. | pmid:8797835 |
| Matias I et al. | Presence and regulation of the endocannabinoid system in human dendritic cells. | 2002 | Eur. J. Biochem. | pmid:12153574 |
| Kapoor S | Modulation of intracellular pathways by anandamide and its evolving role in oncology. | 2013 | Eur. J. Cancer | pmid:23434147 |
| Laezza C et al. | Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. | 2013 | Eur. J. Cancer | pmid:23434151 |
| Rossi C et al. | Endocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: relation with serotonin levels. | 2008 | Eur. J. Clin. Pharmacol. | pmid:18004553 |
| Di Marzo V et al. | Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. | 2009 | Eur. J. Endocrinol. | pmid:19745037 |
| Adermark L et al. | Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. | 2009 | Eur. J. Neurosci. | pmid:19120438 |
| Millns PJ et al. | Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. | 2006 | Eur. J. Neurosci. | pmid:17229097 |
| Sharkey KA et al. | Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. | 2007 | Eur. J. Neurosci. | pmid:17459108 |
| Ryan D et al. | Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. | 2007 | Eur. J. Neurosci. | pmid:17419758 |
| Ahluwalia J et al. | Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro. | 2003 | Eur. J. Neurosci. | pmid:12823468 |
| Sagan S et al. | Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. | 1999 | Eur. J. Neurosci. | pmid:10051770 |
| Cippitelli A et al. | The anandamide transport inhibitor AM404 reduces ethanol self-administration. | 2007 | Eur. J. Neurosci. | pmid:17650118 |
| Ali AB and Todorova M | Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. | 2010 | Eur. J. Neurosci. | pmid:20345910 |
| Lemak MS et al. | Cannabinoid regulation in identified synapse of terrestrial snail. | 2007 | Eur. J. Neurosci. | pmid:18028114 |
| Béquet F et al. | CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. | 2007 | Eur. J. Neurosci. | pmid:18052990 |
| Rivera P et al. | Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. | 2013 | Eur. J. Neurosci. | pmid:23033907 |
| Sousa-Valente J et al. | Anandamide in primary sensory neurons: too much of a good thing? | 2014 | Eur. J. Neurosci. | pmid:24494681 |
| Rea K et al. | Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. | 2014 | Eur. J. Neurosci. | pmid:24494683 |
| Maccarrone M et al. | Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. | 2002 | Eur. J. Neurosci. | pmid:11982628 |
| Chen N et al. | Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. | 2003 | Eur. J. Pharmacol. | pmid:14575792 |
| Shi RZ et al. | Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II. | 2012 | Eur. J. Pharmacol. | pmid:22318155 |
| Saitoh C et al. | The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder. | 2007 | Eur. J. Pharmacol. | pmid:17586490 |
| Basavarajappa BS et al. | Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons. | 2003 | Eur. J. Pharmacol. | pmid:12679143 |
| Guindon J et al. | Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | 2006 | Eur. J. Pharmacol. | pmid:17027744 |
| Fride E and Mechoulam R | Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent. | 1993 | Eur. J. Pharmacol. | pmid:8384116 |
| Smid SD et al. | The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. | 2007 | Eur. J. Pharmacol. | pmid:17706636 |
| Mechoulam R et al. | Endocannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9831287 |
| Ho WS | Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase. | 2013 | Eur. J. Pharmacol. | pmid:23340220 |
| Ghasemi M et al. | Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. | 2006 | Eur. J. Pharmacol. | pmid:16824514 |
| Liu YC and Wu SN | Block of erg current by linoleoylamide, a sleep-inducing agent, in pituitary GH3 cells. | 2003 | Eur. J. Pharmacol. | pmid:12498905 |
| Hao S et al. | Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. | 2000 | Eur. J. Pharmacol. | pmid:10762668 |
| Mukherjee S et al. | Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors. | 2004 | Eur. J. Pharmacol. | pmid:15556131 |
| López-Miranda V et al. | Anandamide vehicles: a comparative study. | 2004 | Eur. J. Pharmacol. | pmid:15556148 |
| Braida D et al. | 5-HT1A receptors are involved in the anxiolytic effect of Delta9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. | 2007 | Eur. J. Pharmacol. | pmid:17116299 |
| Castelli MP et al. | Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2. | 2007 | Eur. J. Pharmacol. | pmid:17644084 |
| Oz M et al. | Endogenous cannabinoid anandamide directly inhibits voltage-dependent Ca(2+) fluxes in rabbit T-tubule membranes. | 2000 | Eur. J. Pharmacol. | pmid:10980258 |
| Smart D et al. | Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology. | 2001 | Eur. J. Pharmacol. | pmid:11301059 |
| Dembiński A et al. | Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves. | 2008 | Eur. J. Pharmacol. | pmid:18593574 |
| Kopczyńska B et al. | Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. | 2011 | Eur. J. Pharmacol. | pmid:21756900 |
| Someya A et al. | Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells. | 2002 | Eur. J. Pharmacol. | pmid:12206851 |
| Richardson JD et al. | Antihyperalgesic effects of spinal cannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9600630 |
| Haller VL et al. | Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. | 2008 | Eur. J. Pharmacol. | pmid:18762181 |
| Berdyshev EV et al. | Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. | 1997 | Eur. J. Pharmacol. | pmid:9253958 |