| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alzheimer Disease | D000544 | 76 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hillard CJ et al. | Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. | 1995 | Biochim. Biophys. Acta | pmid:7647100 |
| Fride E et al. | Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7853184 |
| Adams IB et al. | Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791088 |
| Welch SP et al. | Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791096 |
| Musty RE et al. | A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. | 1995 | Life Sci. | pmid:7776816 |
| Omeir RL et al. | Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. | 1995 | Life Sci. | pmid:7776824 |
| Romero J et al. | The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons. | 1995 | Life Sci. | pmid:7776829 |
| Adams IB et al. | Pharmacological and behavioral evaluation of alkylated anandamide analogs. | 1995 | Life Sci. | pmid:7776830 |
| Wenger T et al. | Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. | 1995 | Life Sci. | pmid:7776832 |
| Cabral GA et al. | Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells. | 1995 | Life Sci. | pmid:7776833 |
| Wiley J et al. | Discriminative stimulus effects of anandamide in rats. | 1995 | Eur. J. Pharmacol. | pmid:7781695 |
| Fan P | Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons. | 1995 | J. Neurophysiol. | pmid:7760148 |
| Ueda N et al. | Oxygenation of arachidonylethanolamide (anandamide) by lipoxygenases. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732825 |
| Facci L et al. | Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7724569 |
| Fride E | Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. | 1995 | Brain Res. | pmid:8593598 |
| Fontana A et al. | Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577784 |
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| Terranova JP et al. | Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors. | 1995 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:8751088 |
| Hampson AJ et al. | Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. | 1995 | Biochim. Biophys. Acta | pmid:7488638 |
| Ueda N | [Anandamide: an endogenous cannabinoid receptor agonist]. | 1995 | Seikagaku | pmid:7594870 |
| Varga K et al. | Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. | 1995 | Eur. J. Pharmacol. | pmid:7589169 |
| Mechoulam R et al. | Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. | 1995 | Biochem. Pharmacol. | pmid:7605349 |
| Felder CC et al. | Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. | 1995 | Mol. Pharmacol. | pmid:7565624 |
| Vela G et al. | Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. | 1995 | Neuropharmacology | pmid:7566503 |
| Paria BC et al. | The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568154 |
| Burstein SH and Hunter SA | Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). | 1995 | Biochem. Pharmacol. | pmid:7702643 |
| Priller J et al. | Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. | 1995 | Mol. Pharmacol. | pmid:7651362 |
| Ellis EF et al. | Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. | 1995 | Am. J. Physiol. | pmid:8594893 |
| Collin C et al. | Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7479747 |
| Pertwee RG et al. | Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. | 1995 | Eur. J. Pharmacol. | pmid:7713152 |
| Hansen HS et al. | Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. | 1995 | Biochim. Biophys. Acta | pmid:7548201 |
| Edgemond WS et al. | The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. | 1995 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784462 |
| Koga D et al. | High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). | 1995 Jan-Feb | Biomed. Chromatogr. | pmid:7734936 |
| Kempe K et al. | Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. | 1996 | J. Biol. Chem. | pmid:8663381 |
| Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
| Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
| Sugiura T et al. | N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. | 1996 | J Lipid Mediat Cell Signal | pmid:8906545 |
| Ueda N et al. | Enzymes for anandamide biosynthesis and metabolism. | 1996 | J Lipid Mediat Cell Signal | pmid:8906546 |
| Yang ZM et al. | Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. | 1996 | Biol. Reprod. | pmid:8879486 |
| Varga K et al. | Mechanism of the hypotensive action of anandamide in anesthetized rats. | 1996 | Hypertension | pmid:8843898 |
| Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
| Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
| Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
| Fride E and Mechoulam R | Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. | 1996 | Brain Res. Dev. Brain Res. | pmid:8873985 |
| Boring DL et al. | Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931121 |
| Berdyshev EV et al. | Anandamide--a new look on fatty acid ethanolamides. | 1996 | J Lipid Mediat Cell Signal | pmid:9029374 |
| Randall MD et al. | An endogenous cannabinoid as an endothelium-derived vasorelaxant. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954092 |
| Paria BC et al. | The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. | 1996 | Mol. Reprod. Dev. | pmid:8914076 |
| Khanolkar AD et al. | Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. | 1996 | J. Med. Chem. | pmid:8893848 |